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Makinen lab - Lymphatic Biology and Pathology

@taijamakinenlab.bsky.social

100 followers 71 following 14 posts

Laboratory at the Wihuri Research Institute @wrihelsinki.bsky.social‬ and University of Helsinki. We investigate mechanisms that regulate the lymphatic vasculature and its role in organ-specific physiology and disease processes.

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Reposted by Makinen lab - Lymphatic Biology and Pathology

Hans schoofs @hansschoofs.bsky.social · Jul 15

This beautiful work from the lab in Uppsala @taijamakinenlab.bs made it to the cover ! Happy to be part of it ! Congrats again to the first author Marle Kraft ! Stunning images

Nature Cardiovascular Research @natcardiovascres.nature.com · Jul 15

❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more!

www.nature.com/natcardiovas...

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Reposted by Makinen lab - Lymphatic Biology and Pathology

Hellmut Augustin @hellmutaugustin.bsky.social · Jul 14

Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jul 4

Congrats Bong-Ihn - exciting news!

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jul 1

I am honoured to be elected as a Member of EMBO and look forward to contributing to its mission and community!

EMBO @embo.org · Jul 1

Welcome and congratulations to the 60 new members and 9 associate members who have been elected to the EMBO Membership! This honour celebrates #research excellence and outstanding achievements in the #LifeSciences. 🧪

Learn more here:
www.embo.org/press-releas... #EMBOMembers2025

Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO

Sixty-nine new members join the community of leading life scientists in Europe and beyond

www.embo.org

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Reposted by Makinen lab - Lymphatic Biology and Pathology

Institute for Molecular Medicine Finland (FIMM) @fimm-uh.bsky.social · Jun 30

📣 We are recruiting 2-3 early-stage group leaders! 📣

Lead your own research group at FIMM @helsinki.fi and help us build more bridges from discovery to medicine!

👉 Apply here by 10 Aug: jobs.helsinki.fi/job/Helsinki...

#GroupLeaderPosition #AcademicCareers #MolecularMedicine

Portrait of Nina Mars, MD, PhD, on a blue gradient background. She is wearing glasses and a black top, with long brown hair. To the right is a quote:
"What drew me to a FIMM group leader position was the chance to do research that doesn’t stop at the discovery stage. At FIMM, we’re also close to the clinic, which means our work stays connected to real patient needs."
Below the quote:
Nina Mars, MD, PhD
FIMM-EMBL Group Leader since 2024
Logos of the University of Helsinki and FIMM are at the top right.

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 26

Congrats Rui - excited to see all the great science to come!

Rui Benedito @ruibenedito.bsky.social · Jun 26

The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil

Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 12

Better image here

Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 12

Thanks to all the supporters who made the #EVBOSummerSchool possible! The Company of Biologists @biologists.bsky.social, The Boehringer Ingelheim Stiftung, @brukerspatial.bsky.social, Genevia Technologies and Triolab.

Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 12

And to the winners of the Poster Awards - sponsored by The Boehringer Ingelheim Stiftung

Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 12

Big congratulations to the winners of the Travel Awards - sponsored by The Company of Biologists @biologists.bsky.social

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 12

We were happy to host the #EVBOSummerSchool in Helsinki earlier this week – huge thanks to all participants for two amazing days full of great talks, posters, and networking! A fantastic showcase of the next generation of #VascularBiology and @evborg.bsky.social community.

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 8

Congratulations!

Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Jun 8

Exciting days ahead at the Wihuri Research Institute @wrihelsinki.bsky.social as we host #WRISymposium and #EVBOSummerSchool next week in Helsinki.

Looking forward to inspiring talks and scientific exchange with the #VascularBiology community!

wri.fi/research-act...
evbo.org/index.php/ev...

Wihuri Research Institute Symposium 2025 - Wihuri Research Institute

Since 2013, the Wihuri Research Institute (WRI) has been organizing the annual WRI Symposium, providing a platform for researchers and students to share knowledge and insights in cardiovascular resear...

wri.fi

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · May 25

We hope these findings bring us closer to better treatments for this challenging condition. #vascularbiology #PIK3CA #venousmalformation

Huge thanks to our fantastic collaborators Michael Potente, René Hägerling, Friedrich Kapp, @mvikkula.bsky.social, Laurence Boon, @ruibenedito.bsky.social

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · May 25

Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in ‪@natcardiovascres.nature.com by Marle Kraft et al.

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Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations

Nature Cardiovascular Research - Kraft et al. identify TIE2 activation as a key driver of PIK3CA-related venous malformations and demonstrate that inhibiting TIE2 signaling can suppress the growth...

rdcu.be

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Mar 20

www.youtube.com/watch?v=seh5...

Why humans have puzzle-shaped cells

YouTube video by nature video

www.youtube.com

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · Mar 20

If you’re curious about why lymphatic endothelial cells have their jigsaw puzzle-like shape,
check out our paper
@Nature
rdcu.be/eejhZ

Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium

Nature - Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result...

rdcu.be

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