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thegutmann.bsky.social
Theresia Gutmann
@thegutmann.bsky.social
160 followers 210 following 5 posts
Scientist exploring molecular mechanisms of cellular recognition and signal processing using biophysical, biochemical, and cell biological approaches. Based @ Max Planck Institute of Molecular Cell Biology and Genetics
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thegutmann.bsky.social
Theresia Gutmann @thegutmann.bsky.social · Jun 24
Excited to share our latest work out in @pnas.org! We show that the #SARSCoV2 nucleocapsid protein directly prevents DNA recognition of the immune sensor #cGAS by competing for DNA, which may delay early innate immune responses during infection. www.pnas.org/doi/epub/10.... #innateimmunity
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thegutmann.bsky.social
Theresia Gutmann @thegutmann.bsky.social · 14d
Abstract submission deadline for the #STS meeting on #SignalTransduction extended to 𝟯𝟬𝘁𝗵 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿. Great line-up of speakers with Hao Wu of Boston Children's Hospital delivering the #STS Honorary Medal: sigtrans.de/meeting-2025 | Weimar, 3-5 November
Meeting 2025 | STS
sigtrans.de
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thegutmann.bsky.social
Theresia Gutmann @thegutmann.bsky.social · 19d
Just wow! Congrats to all the authors.
thegutmann.bsky.social
Theresia Gutmann @thegutmann.bsky.social · Jun 24
For a lay summary in English or German: www.mpi-cbg.de/news-outreac...
How the SARS-CoV-2 virus tricks the DNA alarm system
Dresden scientists discovered a new strategy used by the SARS-CoV-2 virus to hide from the body’s DNA immune detection system.
www.mpi-cbg.de
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Reposted by Theresia Gutmann
mpi-cbg.de
Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Jun 24
Dresden scientists @thegutmann.bsky.social and @rnadavid.bsky.social from the @hymanlab.bsky.social discover a new strategy used by the SARS-CoV-2 virus to hide from the body’s DNA immune detection system. Now published in @pnas.org. www.mpi-cbg.de/news-outreac...
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Reposted by Theresia Gutmann
hymanlab.bsky.social
Hyman Lab @hymanlab.bsky.social · Jun 24
How could SARS-COV-2 evade detection by host cells?

Read the new paper from Theresia @thegutmann.bsky.social
and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS

Congratulations!!!
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thegutmann.bsky.social
Theresia Gutmann @thegutmann.bsky.social · Jun 24
Excited to share our latest work out in @pnas.org! We show that the #SARSCoV2 nucleocapsid protein directly prevents DNA recognition of the immune sensor #cGAS by competing for DNA, which may delay early innate immune responses during infection. www.pnas.org/doi/epub/10.... #innateimmunity
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thegutmann.bsky.social
Theresia Gutmann @thegutmann.bsky.social · Jun 24
Tremendously grateful to my mentor Tony Hyman @hymanlab.bsky.social for his generous support and trust & to our exceptional PhD student David Kuster @rnadavid.bsky.social‬ @mpi-cbg.de‬! Many thanks to @dfg.de, the NOMIS Foundation, @volkswagenstiftung.de, and @maxplanck.de for supporting this work.
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thegutmann.bsky.social
Theresia Gutmann @thegutmann.bsky.social · Jun 24
Excited to share our latest work out in @pnas.org! We show that the #SARSCoV2 nucleocapsid protein directly prevents DNA recognition of the immune sensor #cGAS by competing for DNA, which may delay early innate immune responses during infection. www.pnas.org/doi/epub/10.... #innateimmunity
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