Lightnews — Scholar-powered news

Hyman Lab @hymanlab.bsky.social · 6d

how about giving citations?

Hyman Lab @hymanlab.bsky.social · 19d

🤌

Max Planck Institute for the Physics of Complex Systems @mpipks.bsky.social · 19d

IG Nobel Prize in #Physics 2025 to @mpipks.bsky.social researchers for elucidating the phase behaviour of cacio e pepe sauce. The work highlights how physics can also be applied to solve daily-life problems!

nature.com/articles/d41586-025-03045-0

Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research

The annual awards are a celebration of weird but thought-provoking science.

nature.com

1 6

Hyman Lab @hymanlab.bsky.social · 19d

Very good news in the local press! The Ig Nobel goes to Dresden 😎

www.saechsische.de/lokales/dres...

Dresdner Forscher gewinnen besonderen Nobelpreis für Pastasauce

Kuriose wissenschaftliche Studien sind mit den Ig-Nobelpreisen in den USA geehrt worden. Auch Forscher vom Max-Planck-Institut in Dresden wurden ausgezeichnet.

www.saechsische.de

1 11

Hyman Lab @hymanlab.bsky.social · 22d

Have a look at Lars @larshubatsch.bsky.social reviewed preprint in @elife.bsky.social and learn about the kinetics of molecule transport across interfaces of condensates!

Lars Hubatsch @larshubatsch.bsky.social · 22d

Paper alert!🧪
We derive a theory that underpins interface resistance with a physical foundation and look at how it changes droplet growth and recovery kinetics! Awesome collab with @bosste.bsky.social Tyler Harmon @hymanlab.bsky.social @m-pol.bsky.social and Frank Jülicher @mpipks.bsky.social 1/4

Transport kinetics across interfaces between coexisting liquid phases

elifesciences.org

5

Hyman Lab @hymanlab.bsky.social · Sep 5

Congratulations to Patrick and his team!
Tremendous work carried out over the last years @mpi-cbg.de and @poldresden.bsky.social as collaboration between Hyman lab, Brugues lab and Andrei Shevchenko

Brugues Lab @brugueslab.bsky.social · Sep 3

Patrick's paper is finally out, a label-free method to measure the composition of multicomponent biomolecular condensates!

1 8 26

Reposted by Hyman Lab

André Nadler @nadlerlab.bsky.social · Sep 3

This is an amazing piece of work! It was a true pleasure seeing this story come together.
@mpi-cbg.de going on a streak of @nature.com papers!

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Sep 3

Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social ‬ & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...

Mechanical forces drive evolutionary change

A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.

www.mpi-cbg.de

5 27

Reposted by Hyman Lab

André Nadler @nadlerlab.bsky.social · Aug 21

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...

31 120 330

Reposted by Hyman Lab

Max Planck School Matter to Life @mattertolife.bsky.social · Jul 16

The recent publication from MtL fellow @hymanlab.bsky.social has described a quantitative framework for condensate stability and dissolution, in the context of RNA binding protein MEX-5 and P-granules. Congratulations to MtL Student Silja Zedlitz for being a co-author!
www.pnas.org/doi/10.1073/...

A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro | PNAS

MEX-5 regulates the formation and dissolution of P granules in Caenorhabditis elegans embryos, yet the thermodynamic basis of its activity remains ...

www.pnas.org

1 4

Reposted by Hyman Lab

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Jun 26

Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...

Novel Research in Biological Artificial Intelligence

Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.

www.mpi-cbg.de

29 31

Reposted by Hyman Lab

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Jun 25

How to spy on condensates: technology feature in @natmethods.nature.com on self-organization and collective properties of condensates with quotes from Anthony Hyman @hymanlab.bsky.social @mpi-cbg.de, @brangwynnelab.bsky.social, and many more. www.nature.com/articles/s41...

How to spy on condensates - Nature Methods

Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.

www.nature.com

1 2 12

Reposted by Hyman Lab

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Jun 24

Dresden scientists @thegutmann.bsky.social and @rnadavid.bsky.social from the @hymanlab.bsky.social discover a new strategy used by the SARS-CoV-2 virus to hide from the body’s DNA immune detection system. Now published in @pnas.org. www.mpi-cbg.de/news-outreac...

1 6 15

Hyman Lab @hymanlab.bsky.social · Jun 24

How could SARS-COV-2 evade detection by host cells?

Read the new paper from Theresia @thegutmann.bsky.social
and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS

Congratulations!!!
‬

Theresia Gutmann @thegutmann.bsky.social · Jun 24

Excited to share our latest work out in @pnas.org! We show that the #SARSCoV2 nucleocapsid protein directly prevents DNA recognition of the immune sensor #cGAS by competing for DNA, which may delay early innate immune responses during infection. www.pnas.org/doi/epub/10.... #innateimmunity

4 8

Reposted by Hyman Lab

Physics of Life Dresden @poldresden.bsky.social · Jun 18

Big news 🎉 We are excited to announce the new TUD graduate school "Biomolecular Condensates: From Physics to Biological Functions", with 12 members from PoL! Through this school, we will train a new generation of scientists working on #condensates at the interphase between theory and experiments 🤓⤵️

TU Dresden @tudresden.bsky.social · Jun 16

Hochaktuelles Themenfeld an der Schnittstelle von Physik, Biologie und Polymerforschung: Die @dfg.de fördert ab 2026 mit rund 7 Millionen Euro ein neues Graduiertenkolleg zur Erforschung biomolekularer Kondensate in #Dresden. 🔬
ℹ️ tu-dresden.de/tu-dresden/n...

8 22

Reposted by Hyman Lab

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Jun 18

Visit us during the Dresden Science Night on June 20th in the Faculty of Physics @tudresden.bsky.social (Hermann-Krone-Bau, Nöthnitzer Straße 61) and explore the physics of life! Looking forward to see you! www.mpi-cbg.de/news-outreac...

1 2

Reposted by Hyman Lab

GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · Jun 16

We're excited to welcome Dresden's scientific community to the GBM Compact Meeting in Frankfurt! #CodensateBiology
gbm-compact.org

2 4

Hyman Lab @hymanlab.bsky.social · Jun 16

The german research foundation DFG will fund the new graduate school for

"Biomolecular Condensates: from physics to biological function" here in Dresden

This new graduate school is part of 18 new graduate schools funded by the DFG in germany!

Deutsche Forschungsgemeinschaft @dfg.de · Jun 16

Förderentscheidung für 18 neue #Graduiertenkollegs, darunter 4 internationale Verbünde mit Partnern in den USA, Italien, Kanada und Frankreich. Themen reichen von klimaneutralem Stahl bis zur Erforschung von Infektionserkrankungen . ➡️ www.dfg.de/de/service/p...

1 9 43

Reposted by Hyman Lab

CrowDsourcing COndensate Database & Encyclopedia @cdcode.bsky.social · Jun 11

The latest release was supported by the #condesathon joined by @mpi-cbg.de condensate community🤩

Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜

3 6

Hyman Lab @hymanlab.bsky.social · Jun 4

We had great fun with the lab!

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Jun 4

Thirty-six institute staff members in nine tems participated in the REWE Team Challenge Dresden on Wednesday evening, May 28. Congratulations to all participants! 🎉 www.mpi-cbg.de/news-outreac...

MPI-CBG participates in Dresden 5K running event

Nine teams ran REWE Team Challenge Dresden 2025

www.mpi-cbg.de

3

Reposted by Hyman Lab

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · May 28

Condensates Inside Condensates—Triggering Disease?
New Insights into TDP-43 Condensation and Neurodegeneration. Publication from the @hymanlab.bsky.social in @cellpress.bsky.social, first author: @xiaoyan52802927.bsky.social www.mpi-cbg.de/news-outreac...

Condensates Inside Condensates—Triggering Disease?

New Insights into TDP-43 Condensation and Neurodegeneration

www.mpi-cbg.de

2 5 20

Reposted by Hyman Lab

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · May 27

Watch the related Science Sketch video: youtu.be/uBpPMyVTj5c?..., created by @marionamec.bsky.social

Molecule Disarms Cellular Stress Granules Linked to ALS

YouTube video by MPI-CBG

youtu.be

5 7

Reposted by Hyman Lab

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · May 27

A team @mpi-cbg.de from @hymanlab.bsky.social & the @edinburghup.bsky.social (Richard Wheeler group) has identified the molecule lipoamide that can prevent the formation of pathological stress granules - protein-rich condensates associated with cellular stress and ALS. www.mpi-cbg.de/news-outreac...

Molecule Disarms Cellular Stress Granules Linked to ALS

Discovery by researchers in Dresden and Edinburgh points to new understanding of the onset of ALS.

www.mpi-cbg.de

2 6 23

Hyman Lab @hymanlab.bsky.social · May 24

4

Hyman Lab @hymanlab.bsky.social · May 23

"targeting intra-condensate demixing of TDP-43 within stress granules, as a distinct step to aggregation, becomes a potential avenue for therapeutic intervention"

2

Hyman Lab @hymanlab.bsky.social · May 23

"Our key finding is that TDP-43 aggregation requires a double event. One event is the increase in TDP-43 con- centration within stress granules surpassing a critical threshold, and the other is oxidative stress promoting TDP-43 self-interaction"

1 1

Hyman Lab @hymanlab.bsky.social · May 23

Importantly, demixing of TDP-43 occurs in iPS-motor neurons, in a disease mouse model and in patients

1