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André Nadler

@nadlerlab.bsky.social

2.1K followers 1.6K following 490 posts

Chemist in a CellBio place. Fan of lipids & membranes

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André Nadler @nadlerlab.bsky.social · Aug 21

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...

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Reposted by André Nadler

Naomi Moris @nmoris.bsky.social · 8h

The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍

The Francis Crick Institute @crick.ac.uk · 10h

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

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André Nadler @nadlerlab.bsky.social · 4h

Thanks!

Reposted by André Nadler

Erdinc Sezgin @sciezgin.bsky.social · 2d

Cell Physics community is missing Jochen Guck deeply.. He was a very kind and generous person, one of the most creative minds, and always ready to help everyone in the field.. He inspired many of us.. He will always be missed..

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André Nadler @nadlerlab.bsky.social · 9h

#lipidtime alert!
This preprint by Kenji Maeda (cannot find him here) & colleagues is mandatory reading by everybody with even a cursory interest in lipid biology:
www.biorxiv.org/content/10.1...

Lipid Landscape of human cells

Eukaryotic cells synthesise thousands of lipid species, yet the principles that organise them across compartments remain unclear. Here we introduce PAP-SL, parallel (immuno)affinity purification coupl...

www.biorxiv.org

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André Nadler @nadlerlab.bsky.social · 10h

Thanks to Kristin!

Reposted by André Nadler

Cambridge Morphogenesis Seminar Series @cammorphoseries.bsky.social · 11h

Next Monday, 13th October, at 2:30 pm (UK time), Anne Grapin-Botton will kick off the new term of the Cambridge Morphogenesis Seminar Series! Don't forget to subscribe to our mailing list to get the Zoom link!

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André Nadler @nadlerlab.bsky.social · 11h

Many thanks!

André Nadler @nadlerlab.bsky.social · 12h

Thanks!

André Nadler @nadlerlab.bsky.social · 12h

Thanks!

André Nadler @nadlerlab.bsky.social · 14h

Thanks Jeremy! I obviously fully agree...

André Nadler @nadlerlab.bsky.social · 15h

Yay 🌶️🌶️🌶️

André Nadler @nadlerlab.bsky.social · 15h

Thanks a lot! An I am of course humbled by finally being admitted to the club.

André Nadler @nadlerlab.bsky.social · 16h

Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...

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Reposted by André Nadler

Miki Ebisuya @ebisuyamiki.bsky.social · 1d

New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
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doi.org/10.1101/2025...

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André Nadler @nadlerlab.bsky.social · 18h

This is going to be fun - we are really pleased with the program - there is some really exciting science on the menu! Do sign up!

GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · 18h

Registration open: 77. Mosbacher Kolloquium "More than lipidic barriers - New horizons in membrane biology" from March 25-28, 2026
lnkd.in/dgsW4c3

Scientific Organizers: Britta Brügger, Robert Ernst, André Nadler, Christian Ungermann
Early registration & poster abstracts until January 31, 2026

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André Nadler @nadlerlab.bsky.social · 1d

Terrible news and a great loss for the community. Jochen was an inspiring scientist. My condolences to his family, his coworkers and colleagues.

André Nadler @nadlerlab.bsky.social · 2d

There's a certain chance that it'll be both

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André Nadler @nadlerlab.bsky.social · 2d

Absolutely. But they already got their Nobel.

André Nadler @nadlerlab.bsky.social · 3d

Cool. Really cool. You kind of expect it from Reto.

Reto Fiolka @retof.bsky.social · 3d

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...

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André Nadler @nadlerlab.bsky.social · 6d

I loved this when I first saw it half a year ago & the final version is amazing. These tools will help many groups -

Abhishek Chatterjee @achemsynbio.bsky.social · 7d

Excited to share our work with Eranthie Weerapana and Tim van Opijnen, co-led by Conor Loynd, Soumya Roy, and Sarah Canarelli! We introduce a new generation of BONCAT tools for the versatile characterization of newly synthesized proteins in pathogenic bacteria. rdcu.be/eI4M5

Cell-selective multiplexed bioorthogonal noncanonical amino acid tagging for nascent proteomics

Nature Chemical Biology - Engineered aminoacyl-tRNA synthetase (aaRS) mutants have been developed that facilitate ultrafast bioorthogonal noncanonical amino acid tagging (BONCAT) of newly...

rdcu.be

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André Nadler @nadlerlab.bsky.social · 6d

Not sure about that.

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André Nadler @nadlerlab.bsky.social · 6d

Very exciting work. Shows how interfering with the levels of one lipid class leads to changes of other lipids that are not directly metabolically connected as the cell tries to maintain both lipid flux balance and biophysical membrane properties.

Jeremy Baskin @jeremybaskin.bsky.social · 6d

How do cells sense & respond to lipid imbalances? What happens when a disease-relevant enzyme is blocked? Shiying Huang investigates phosphoinositide lipids with the Balla lab & discovers an integrated cellular response that boosts alternate lipid synthesis pathways! www.biorxiv.org/content/10.1...

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Reposted by André Nadler

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 7d

Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...

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André Nadler @nadlerlab.bsky.social · 8d

This is a beautiful piece of work - makes so many new approaches possible. Congrats to everybody involved!

Thorn-Seshold Lab @thornsesholdlab.bsky.social · 8d

Molecular Recording with HaloTag?
H2O2, GSH, Trx, LAP?

→ multiplexable reagents record diverse enzyme activities ratiometrically, without signal loss

@biorxivpreprint.bsky.social
preprint: doi.org/10.1101/2025...

CHalo Crew again programming with HaloTag!
#chembio #fluorescence #wednesday

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André Nadler @nadlerlab.bsky.social · 10d

Congratulations! Looking forward to giving this an in-depth look!

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