The Journal of Pain
@thejournalofpain.bsky.social
The Journal of Pain is the official journal of @usasp.bsky.social
The journal publishes original articles related to all aspects of pain.
The journal publishes original articles related to all aspects of pain.
Original: Drs. Hildenbrand, Gordon, and Salamon sought to develop an innovative curriculum for health care teams to combat racial injustice related to pain management.
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
December 26, 2025 at 10:30 PM
Original: Drs. Hildenbrand, Gordon, and Salamon sought to develop an innovative curriculum for health care teams to combat racial injustice related to pain management.
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Original: Drs. Beasley & Macfarlane (@uniofaberdeen.bsky.social) conducted a cross-sectional analysis to estimate how changes in physical activity and body mass index might affect prevalence of high-impact chronic pain.
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
December 26, 2025 at 1:30 PM
Original: Drs. Beasley & Macfarlane (@uniofaberdeen.bsky.social) conducted a cross-sectional analysis to estimate how changes in physical activity and body mass index might affect prevalence of high-impact chronic pain.
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
Original: Drs. Kell, Rudy, et al. examined neighborhood socioeconomic factors and pain in Native Americans and non-Hispanic Whites.
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
December 25, 2025 at 10:30 PM
Original: Drs. Kell, Rudy, et al. examined neighborhood socioeconomic factors and pain in Native Americans and non-Hispanic Whites.
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Original: Drs. Antcliff, Holden & coll. (@keeleuniversity.bsky.social) presented the Activity Pacing Questionnaire (APQ-12): a reliable tool to measure activity pacing and its effects on chronic pain symptoms
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
December 25, 2025 at 1:30 PM
Original: Drs. Antcliff, Holden & coll. (@keeleuniversity.bsky.social) presented the Activity Pacing Questionnaire (APQ-12): a reliable tool to measure activity pacing and its effects on chronic pain symptoms
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
Original: Drs. Thomas, Overstreet, et al. examined the relationship between adverse childhood experiences (ACEs) and conditioned pain modulation (CPM) in adults with chronic low back pain (cLBP).
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
December 24, 2025 at 10:30 PM
Original: Drs. Thomas, Overstreet, et al. examined the relationship between adverse childhood experiences (ACEs) and conditioned pain modulation (CPM) in adults with chronic low back pain (cLBP).
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Original: Drs. Wu, Cong et al. showed that the development of pain response (flexion withdrawal reflex) in preterm infants matures from birth up to 2 years old.
—early pain or stress exposure can alter how this system develops
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—early pain or stress exposure can alter how this system develops
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www.jpain.org
December 24, 2025 at 1:30 PM
Original: Drs. Wu, Cong et al. showed that the development of pain response (flexion withdrawal reflex) in preterm infants matures from birth up to 2 years old.
—early pain or stress exposure can alter how this system develops
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—early pain or stress exposure can alter how this system develops
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Orginal: Drs. Raghuraman, @luanacolloca.bsky.social & co. demonstrate comparable placebo analgesia in chronic pain and pain-free individuals overall, but reduced placebo analgesia among those with chronic pain and distressed socioeconomic position
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The effects of socioeconomic position on endogenous pain modulation: A quasi-experimental approach
Socioeconomic Position (SEP) is a multidimensional construct encompassing education, income, occupation, and neighborhood distress, influencing chronic pain severity, interference, and duration.…
www.jpain.org
December 23, 2025 at 10:30 PM
Orginal: Drs. Raghuraman, @luanacolloca.bsky.social & co. demonstrate comparable placebo analgesia in chronic pain and pain-free individuals overall, but reduced placebo analgesia among those with chronic pain and distressed socioeconomic position
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Original: Drs. Lacombe-Thibault & Coll (@ulaval.ca) explored the relationship between uncertainty, pain learning and perception using hierarchical Bayesian modeling.
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
December 23, 2025 at 1:30 PM
Original: Drs. Lacombe-Thibault & Coll (@ulaval.ca) explored the relationship between uncertainty, pain learning and perception using hierarchical Bayesian modeling.
FREE: www.jpain.org/article/S152...
FREE: www.jpain.org/article/S152...
Original: Drs. Martin, Kain et al. (@ucirvine.bsky.social) highlight the incidence of severe pain-related impairment among pediatric patients diagnosed with unspecified abdominal pain in a pediatric emergency department
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
December 22, 2025 at 10:30 PM
Original: Drs. Martin, Kain et al. (@ucirvine.bsky.social) highlight the incidence of severe pain-related impairment among pediatric patients diagnosed with unspecified abdominal pain in a pediatric emergency department
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Original: Drs. @larssonrobin.bsky.social, LoMartire et al. reviewed key risk factors for long-term sickness absence in individuals with high-impact chronic pain.
—support workforce reintegration and reduce individual suffering and societal costs.
FREE: www.jpain.org/article/S152...
—support workforce reintegration and reduce individual suffering and societal costs.
FREE: www.jpain.org/article/S152...
December 22, 2025 at 1:30 PM
Original: Drs. @larssonrobin.bsky.social, LoMartire et al. reviewed key risk factors for long-term sickness absence in individuals with high-impact chronic pain.
—support workforce reintegration and reduce individual suffering and societal costs.
FREE: www.jpain.org/article/S152...
—support workforce reintegration and reduce individual suffering and societal costs.
FREE: www.jpain.org/article/S152...
Original: Drs. Lim, Kain & colleagues (@ucirvine.bsky.social)
summarize factors contributing to pain disparities among non-English-speaking children
—clinician bias, misunderstandings of pain concepts, and lack of interpretation contribute to these disparities
Full: www.jpain.org/article/S152...
summarize factors contributing to pain disparities among non-English-speaking children
—clinician bias, misunderstandings of pain concepts, and lack of interpretation contribute to these disparities
Full: www.jpain.org/article/S152...
December 19, 2025 at 10:30 PM
Original: Drs. Lim, Kain & colleagues (@ucirvine.bsky.social)
summarize factors contributing to pain disparities among non-English-speaking children
—clinician bias, misunderstandings of pain concepts, and lack of interpretation contribute to these disparities
Full: www.jpain.org/article/S152...
summarize factors contributing to pain disparities among non-English-speaking children
—clinician bias, misunderstandings of pain concepts, and lack of interpretation contribute to these disparities
Full: www.jpain.org/article/S152...
Original: Dr. Sanabria-Mazo & Luciano et al. examined the properties of the Spanish version of the Stigma Scale for Chronic Illnesses 8-item version (SSCI-8) in people with chronic pain.
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
December 19, 2025 at 6:35 PM
Original: Dr. Sanabria-Mazo & Luciano et al. examined the properties of the Spanish version of the Stigma Scale for Chronic Illnesses 8-item version (SSCI-8) in people with chronic pain.
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Original: Dr. @katelynnboerner.bsky.social, Oberlander et al. found that autistic children and young people are largely absent from reviews of chronic pain treatments
—Existing studies are highly variable, limiting clear conclusions
FREE: www.jpain.org/article/S152...
—Existing studies are highly variable, limiting clear conclusions
FREE: www.jpain.org/article/S152...
December 18, 2025 at 10:45 PM
Original: Dr. @katelynnboerner.bsky.social, Oberlander et al. found that autistic children and young people are largely absent from reviews of chronic pain treatments
—Existing studies are highly variable, limiting clear conclusions
FREE: www.jpain.org/article/S152...
—Existing studies are highly variable, limiting clear conclusions
FREE: www.jpain.org/article/S152...
Original: Drs. Gao, Wang & co. identified structural and functional brain features, pathways, and candidate genes that may underlie pain chronification
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Dissecting the neurogenetic architecture of chronic pain: A brain-wide genetics study
Chronic pain (CP) is a widespread and debilitating condition with complex neurobiological
and genetic foundations. To better understand the brain-based and genetic mechanisms
underlying CP, we integra...
www.jpain.org
December 18, 2025 at 4:20 PM
Original: Drs. Gao, Wang & co. identified structural and functional brain features, pathways, and candidate genes that may underlie pain chronification
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Review: Stocking, Dr. Sorge at al. reviewed the intersectional impact of stress and mental health on chronic pain and the unequal risk for transgender individuals
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Understanding risk of chronic pain development and related mental health disparities among transgender people: A review of current literature and future directions
Biomedical and clinical research has traditionally focused on binary sex assignments as opposed to gender identity. This oversight has resulted in other gender minority populations being…
www.jpain.org
December 17, 2025 at 10:30 PM
Review: Stocking, Dr. Sorge at al. reviewed the intersectional impact of stress and mental health on chronic pain and the unequal risk for transgender individuals
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Original: Drs. @westernsydneyu.bsky.social & Catley et al. investigated the convergent validity of the Pelvic Pain Psychological Screening Questionnaire (3PSQ).
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Screening psychological factors in pelvic pain: Validation of the pelvic pain psychological screening questionnaire (3PSQ)
The Pelvic Pain Psychological Screening Questionnaire (3PSQ) was developed to assess psychological distress in people with persistent pelvic pain. This study aimed to investigate its psychometric…
www.jpain.org
December 17, 2025 at 1:30 PM
Original: Drs. @westernsydneyu.bsky.social & Catley et al. investigated the convergent validity of the Pelvic Pain Psychological Screening Questionnaire (3PSQ).
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Dr. @emerriwether et al. launch the Special Issue on Pain Disparities, centering equity in pain research and care and calling for collective action to address systemic drivers of pain inequities
Joint call to action paper—Pain disparities special issues: Why this, why now? A unified call at a critical time
For decades, research has demonstrated that pain is not experienced equally, with its burden falling disproportionately on marginalized and oppressed communities.1 These companion special issues of…
www.jpain.org
December 16, 2025 at 10:30 PM
Dr. @emerriwether et al. launch the Special Issue on Pain Disparities, centering equity in pain research and care and calling for collective action to address systemic drivers of pain inequities
Original: Drs. Cornec & Dubois et al. (@univbrest.bsky.social) aimed to measure the incidence of care-induced pain in adults with physical disability, and aimed to identify risk factors and prevention methods used.
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Incidence and risk factors for care-induced pain in adults with physical disability: An observational study
Care facilities for adults with physical disability provide a range of personal, medical care and rehabilitation support involving physical contact. Little is known about pain induced by these…
www.jpain.org
December 16, 2025 at 1:30 PM
Original: Drs. Cornec & Dubois et al. (@univbrest.bsky.social) aimed to measure the incidence of care-induced pain in adults with physical disability, and aimed to identify risk factors and prevention methods used.
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New Special Issue is out: Pain Disparities led by Dr. Bartley et al.
Exploring how inequities shape chronic pain, spotlighting social determinants and inclusive care, and calling for sustained investment in justice-centered pain science
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Exploring how inequities shape chronic pain, spotlighting social determinants and inclusive care, and calling for sustained investment in justice-centered pain science
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Emerging approaches to addressing longstanding inequities: Insights from the Journal of Pain special issue on pain disparities
Pain is a universal human experience, but its treatment is not. Chronic pain is a pervasive global public health crisis, affecting more than 20% of the world’s population.1,2 Yet the burden of pain…
www.jpain.org
December 15, 2025 at 10:30 PM
New Special Issue is out: Pain Disparities led by Dr. Bartley et al.
Exploring how inequities shape chronic pain, spotlighting social determinants and inclusive care, and calling for sustained investment in justice-centered pain science
Full:
Exploring how inequities shape chronic pain, spotlighting social determinants and inclusive care, and calling for sustained investment in justice-centered pain science
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Original: Drs. Hefner, Leffler et al. found that topical ambroxol may treat focal neuropathic pain by targeting Nav1.8, TRPA1, and TRPV1 channels in sensory neurons.
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Nav1.8, TRPV1 and TRPA1 as possible targets of ambroxol when used for topical treatment of neuropathic pain
Sodium channels and the capsaicin receptor TRPV1 in epidermal sensory nerve endings are established targets for topical treatment of neuropathic pain. The secretolytic ambroxol induces effective…
www.jpain.org
December 15, 2025 at 1:30 PM
Original: Drs. Hefner, Leffler et al. found that topical ambroxol may treat focal neuropathic pain by targeting Nav1.8, TRPA1, and TRPV1 channels in sensory neurons.
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FREE:
Original: Drs. Tamargo, Cruz-Almeida et al. ( @ufresearch.bsky.social) found that high-impact pain may contribute to cognitive impairment, especially in individuals without the high-risk APOE4 allele
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
High-impact pain predicts subjective cognitive decline and interacts with APOE4 genotype in the development of objective cognitive impairment
Chronic pain is the most common health challenge for older adults and a significant risk factor for cognitive impairments and dementia. This study examined the relationship of high-impact pain (i.e.,…
www.jpain.org
December 12, 2025 at 1:30 PM
Original: Drs. Tamargo, Cruz-Almeida et al. ( @ufresearch.bsky.social) found that high-impact pain may contribute to cognitive impairment, especially in individuals without the high-risk APOE4 allele
Full: www.jpain.org/article/S152...
Full: www.jpain.org/article/S152...
Original: Ibitoye & Stinson et al. (@news.ubc.ca) explored healthcare providers’ experience with non-pharmacological interventions for managing sickle cell crisis pain in adolescents in Nigeria.
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You only work with what you know: Healthcare providers’ experiences using non-pharmacological interventions in managing sickle cell crisis pain in adolescents
Sickle cell crises are the leading reason for hospitalization in adolescents with sickle cell disease. Non-pharmacological interventions are recommended for sickle cell crisis pain management in high…
www.jpain.org
December 11, 2025 at 1:30 PM
Original: Ibitoye & Stinson et al. (@news.ubc.ca) explored healthcare providers’ experience with non-pharmacological interventions for managing sickle cell crisis pain in adolescents in Nigeria.
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Original: Drs. Piers & Lucas et al. assessed the association of musculoskeletal pain with quality-of-life at age 18 and whether experimental pain responses at age 13 predict future quality-of-life.
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Long-term effect of pain history and experimental pain responses on adolescents’ quality-of-life: A cohort study
Pain has been shown to impact quality-of-life, but less is known on whether adverse pediatric pain profiles predict long-term quality-of-life in non-clinical populations. We aimed to (1) assess the…
www.jpain.org
December 10, 2025 at 1:30 PM
Original: Drs. Piers & Lucas et al. assessed the association of musculoskeletal pain with quality-of-life at age 18 and whether experimental pain responses at age 13 predict future quality-of-life.
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Original: Drs. van der Miesen & @judpet.bsky.social et al. investigated profiles of habituation and sensitization to pain.
—Repeated painful electrical stimulation results in variable response patterns
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—Repeated painful electrical stimulation results in variable response patterns
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Assessing the reliability and association of pain ratings and skin conductance responses: Insights from habituation and sensitization to pain
Repeated painful stimulation results in substantial inter-individual differences in habituation and sensitization. The extent to which these responses reflect state versus trait characteristics…
www.jpain.org
December 9, 2025 at 1:30 PM
Original: Drs. van der Miesen & @judpet.bsky.social et al. investigated profiles of habituation and sensitization to pain.
—Repeated painful electrical stimulation results in variable response patterns
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—Repeated painful electrical stimulation results in variable response patterns
FREE:
Focus: Drs. @yannickgilanyi.bsky.social, @james-mcauley.bsky.social et al. reviewed the benefits and harms of amputation for complex regional pain syndrome
—the unclear benefits and likely harms should be considered carefully
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—the unclear benefits and likely harms should be considered carefully
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Amputation for complex regional pain syndrome: A systematic review
Complex regional pain syndrome (CRPS) is a disabling pain condition, usually confined to a single limb. Amputation of the affected limb is sometimes performed to improve pain and function for…
www.jpain.org
December 8, 2025 at 1:30 PM
Focus: Drs. @yannickgilanyi.bsky.social, @james-mcauley.bsky.social et al. reviewed the benefits and harms of amputation for complex regional pain syndrome
—the unclear benefits and likely harms should be considered carefully
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—the unclear benefits and likely harms should be considered carefully
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