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A nonprofit organization that has provided independent reviews of drugs and therapeutics since 1959. Funded solely by subscriptions and donations. Because the source matters.
Zurnai, an autoinjector formulation of the opioid antagonist nalmefene, has been approved by the FDA for IM or SC emergency treatment of known or suspected opioid overdose in persons ≥12 years old medicalletter.org/nalme746b
January 9, 2026 at 7:15 PM
Zurnai, an autoinjector formulation of the opioid antagonist nalmefene, has been approved by the FDA for IM or SC emergency treatment of known or suspected opioid overdose in persons ≥12 years old medicalletter.org/nalme746b
The FDA has approved Tonmya (Tonix), a sublingual tablet formulation of the skeletal muscle relaxant cyclobenzaprine, for treatment of fibromyalgia in adults
medicalletter.org/cyclo746a
medicalletter.org/cyclo746a
January 8, 2026 at 4:10 PM
The FDA has approved Tonmya (Tonix), a sublingual tablet formulation of the skeletal muscle relaxant cyclobenzaprine, for treatment of fibromyalgia in adults
medicalletter.org/cyclo746a
medicalletter.org/cyclo746a
Read our latest issue: secure.medicalletter.org/TML-issue-1746
#Fibromyalgia #OpioidOverdose #HAE #BreastCancer
#Fibromyalgia #OpioidOverdose #HAE #BreastCancer
January 7, 2026 at 3:12 PM
Read our latest issue: secure.medicalletter.org/TML-issue-1746
#Fibromyalgia #OpioidOverdose #HAE #BreastCancer
#Fibromyalgia #OpioidOverdose #HAE #BreastCancer
Gepotidacin (Blujepa) — A New Antibiotic for Uncomplicated UTI medicalletter.org/gepo745a
January 6, 2026 at 3:13 PM
Gepotidacin (Blujepa) — A New Antibiotic for Uncomplicated UTI medicalletter.org/gepo745a
Read our latest issue: bit.ly/4jhEzHY
December 31, 2025 at 7:09 PM
Read our latest issue: bit.ly/4jhEzHY
December 17, 2025 at 10:08 PM
December 17, 2025 at 9:27 PM
It’s Trivia Tuesday! This question is from our Article Noninsulin Drugs for Type 2 Diabetes medicalletter.org/noninsul742a
December 16, 2025 at 10:27 PM
It’s Trivia Tuesday! This question is from our Article Noninsulin Drugs for Type 2 Diabetes medicalletter.org/noninsul742a
Elinzanetant (Lynkuet) for Menopausal Vasomotor Symptoms
Free access: medicalletter.org/elinz744b
Free access: medicalletter.org/elinz744b
December 15, 2025 at 9:09 PM
Elinzanetant (Lynkuet) for Menopausal Vasomotor Symptoms
Free access: medicalletter.org/elinz744b
Free access: medicalletter.org/elinz744b
Expanded Indication for PCSK9 Inhibitors
Free access: medicalletter.org/pcsk744a
#PCSK9 #CardiovascularRisk #FOAMed
Free access: medicalletter.org/pcsk744a
#PCSK9 #CardiovascularRisk #FOAMed
December 11, 2025 at 7:44 PM
Expanded Indication for PCSK9 Inhibitors
Free access: medicalletter.org/pcsk744a
#PCSK9 #CardiovascularRisk #FOAMed
Free access: medicalletter.org/pcsk744a
#PCSK9 #CardiovascularRisk #FOAMed
December 11, 2025 at 7:22 PM
Comparison Chart: Some Available Insulins for Type 2 Diabetes bit.ly/48Thec0
#Insulins #Type2Diabetes #FOAMed
#Insulins #Type2Diabetes #FOAMed
December 4, 2025 at 7:10 PM
Comparison Chart: Some Available Insulins for Type 2 Diabetes bit.ly/48Thec0
#Insulins #Type2Diabetes #FOAMed
#Insulins #Type2Diabetes #FOAMed
For more than 60 years, The Medical Letter has been the independent, objective voice among the many sources of medical information that are directly and indirectly funded by the pharmaceutical industry. To contribute on this #GivingTuesday: secure.medicalletter.org/donation/
#Nonprofit
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December 2, 2025 at 12:55 PM
For more than 60 years, The Medical Letter has been the independent, objective voice among the many sources of medical information that are directly and indirectly funded by the pharmaceutical industry. To contribute on this #GivingTuesday: secure.medicalletter.org/donation/
#Nonprofit
#Nonprofit
A Cardiovascular Indication for Oral Semaglutide (Rybelsus) bit.ly/441JSoz
December 1, 2025 at 5:36 PM
A Cardiovascular Indication for Oral Semaglutide (Rybelsus) bit.ly/441JSoz
It’s Trivia Tuesday! This question is from our In Brief: Primary Aldosteronism Screening in Patients with Hypertension bit.ly/3XkKVfB
November 25, 2025 at 6:59 PM
It’s Trivia Tuesday! This question is from our In Brief: Primary Aldosteronism Screening in Patients with Hypertension bit.ly/3XkKVfB
Donidalorsen (Dawnzera – Ionis), a subcutaneously injected prekallikrein-directed antisense oligonucleotide, has been approved by the FDA for prevention of hereditary angioedema (HAE) attacks in patients ≥12 years old. bit.ly/48wX0Vh
November 24, 2025 at 4:19 PM
Donidalorsen (Dawnzera – Ionis), a subcutaneously injected prekallikrein-directed antisense oligonucleotide, has been approved by the FDA for prevention of hereditary angioedema (HAE) attacks in patients ≥12 years old. bit.ly/48wX0Vh
Free Comparison Chart: GLP-1 and GIP/GLP-1 Receptor Agonists for Type 2 Diabetes bit.ly/3JIu2Zd
#FOAMed #Type2Diabetes #GLP1
#FOAMed #Type2Diabetes #GLP1
November 19, 2025 at 5:49 PM
Free Comparison Chart: GLP-1 and GIP/GLP-1 Receptor Agonists for Type 2 Diabetes bit.ly/3JIu2Zd
#FOAMed #Type2Diabetes #GLP1
#FOAMed #Type2Diabetes #GLP1
Free Comparison Chart: Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors secure.medicalletter.org/TML-article-...
#FOAMed #Type2Diabetes #SGLT2
#FOAMed #Type2Diabetes #SGLT2
November 13, 2025 at 2:05 PM
Free Comparison Chart: Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors secure.medicalletter.org/TML-article-...
#FOAMed #Type2Diabetes #SGLT2
#FOAMed #Type2Diabetes #SGLT2
Read our latest issue- Free access to our article Noninsulin Drugs for Type 2 Diabetes medicalletter.org/noninsul742a
#FOAMed #Type2Diabetes
#FOAMed #Type2Diabetes
November 12, 2025 at 2:43 PM
Read our latest issue- Free access to our article Noninsulin Drugs for Type 2 Diabetes medicalletter.org/noninsul742a
#FOAMed #Type2Diabetes
#FOAMed #Type2Diabetes
Updates for Lecanemab (Leqembi) for Alzheimer's Disease
Read for free: bit.ly/495YIxD
#AlzheimersDisease #FOAMed
Read for free: bit.ly/495YIxD
#AlzheimersDisease #FOAMed
November 6, 2025 at 5:04 PM
Updates for Lecanemab (Leqembi) for Alzheimer's Disease
Read for free: bit.ly/495YIxD
#AlzheimersDisease #FOAMed
Read for free: bit.ly/495YIxD
#AlzheimersDisease #FOAMed
It’s Trivia Tuesday! This question is from our article Antiviral Drugs for Seasonal Influenza for 2025-2026 bit.ly/3X8lb5Y
November 4, 2025 at 8:49 PM
It’s Trivia Tuesday! This question is from our article Antiviral Drugs for Seasonal Influenza for 2025-2026 bit.ly/3X8lb5Y
Free Open-Access article: Sulopenem Etzadroxil/Probenecid (Orlynvah) for Uncomplicated UTIs medicalletter.org/sulop741b
#UTI #FOAMed
#UTI #FOAMed
November 3, 2025 at 3:38 PM
Free Open-Access article: Sulopenem Etzadroxil/Probenecid (Orlynvah) for Uncomplicated UTIs medicalletter.org/sulop741b
#UTI #FOAMed
#UTI #FOAMed
Advance Release Article: A Cardiovascular Indication for Oral Semaglutide (Rybelsus) bit.ly/4nsRXJK
October 30, 2025 at 1:16 PM
Advance Release Article: A Cardiovascular Indication for Oral Semaglutide (Rybelsus) bit.ly/4nsRXJK
Acetaminophen should remain the drug of choice for fever and pain during pregnancy.
Read more in our Open-Access Advance Release article: Prenatal Acetaminophen Use and Autism bit.ly/49lz3B4
#Tylenol #acetaminophen #autism #FOAMed
Read more in our Open-Access Advance Release article: Prenatal Acetaminophen Use and Autism bit.ly/49lz3B4
#Tylenol #acetaminophen #autism #FOAMed
October 27, 2025 at 7:27 PM
Acetaminophen should remain the drug of choice for fever and pain during pregnancy.
Read more in our Open-Access Advance Release article: Prenatal Acetaminophen Use and Autism bit.ly/49lz3B4
#Tylenol #acetaminophen #autism #FOAMed
Read more in our Open-Access Advance Release article: Prenatal Acetaminophen Use and Autism bit.ly/49lz3B4
#Tylenol #acetaminophen #autism #FOAMed
Free Open-Access article: Intravesical Gemcitabine (Inlexzo) for Bladder Cancer secure.medicalletter.org/TML-article-...
#FOAMed #BladderCancer
#FOAMed #BladderCancer
October 23, 2025 at 7:08 PM
Free Open-Access article: Intravesical Gemcitabine (Inlexzo) for Bladder Cancer secure.medicalletter.org/TML-article-...
#FOAMed #BladderCancer
#FOAMed #BladderCancer