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The Medical Letter
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A nonprofit organization that has provided independent reviews of drugs and therapeutics since 1959. Funded solely by subscriptions and donations. Because the source matters.
Answer: d
Rash and mild injection-site reactions have also occurred. Very low LDL-C levels due to PCSK9 inhibitor use have not been associated with adverse clinical effects.
January 13, 2026 at 6:26 PM
Answer: a
in adults with heart failure (reduced or preserved ejection fraction), an SGLT2 inhibitor is recommended. In those with symptomatic heart failure with preserved ejection fraction and obesity, a GLP-1 receptor agonist is recommended.
December 16, 2025 at 10:33 PM
Answer: d
Screening is also recommended in hypertensive patients with resistant disease, an incidentally discovered adrenal mass, or a family history of early-onset hypertension or stroke.
November 25, 2025 at 7:00 PM