Arthur Mortha
@theonlylabever.bsky.social
Immunology Professor at the University of Toronto
Canadian Research Chair in Mucosal Immunology
Host-Microbiota interactions
Innate Lymphoid Cells
Macrophages
Protozoa
#theonlylabever #punkrockthursday @nkg2d1
https://theonlylabever.com/
Canadian Research Chair in Mucosal Immunology
Host-Microbiota interactions
Innate Lymphoid Cells
Macrophages
Protozoa
#theonlylabever #punkrockthursday @nkg2d1
https://theonlylabever.com/
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ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
January 22, 2026 at 5:00 PM
Please share and distribute
ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
Please share and distribute
ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
January 22, 2026 at 4:54 PM
Please share and distribute
ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
ILC6 6th International Conference on Innate Lymphoid Cells
in Vancouver, BC Canada
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available!!! Get those hot abstracts out.
Please share and distribute
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
January 15, 2026 at 2:42 PM
Please share and distribute
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
www.ilc6vancouver.com
abstract submission and registration open
abstract submission and registration open
January 13, 2026 at 7:32 PM
www.ilc6vancouver.com
abstract submission and registration open
abstract submission and registration open
#Immunosky people! 6th International Conference on Innate Lymphoid Cells - ILC6 in Vancouver.
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
November 21, 2025 at 10:03 PM
#Immunosky people! 6th International Conference on Innate Lymphoid Cells - ILC6 in Vancouver.
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
Happy to share new work from #theonlylabever, lead by the phenomenal @sltai.bsky.social - who developed a tool to study the biology of ILC3s, identifying their role in controlling CSF2-dependent myeloid cells. 🤗
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
October 15, 2025 at 5:11 AM
Happy to share new work from #theonlylabever, lead by the phenomenal @sltai.bsky.social - who developed a tool to study the biology of ILC3s, identifying their role in controlling CSF2-dependent myeloid cells. 🤗
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
@mucosalimmunol.bsky.social @societymucosalimm.bsky.social
OA: doi.org/10.1016/j.mu...
I am very thankful to all our fantastic collaborators and members of #theonlylabever for their hard work and important contributions! It a privilege to work with you 😘
December 19, 2024 at 9:30 PM
I am very thankful to all our fantastic collaborators and members of #theonlylabever for their hard work and important contributions! It a privilege to work with you 😘
12) In summary, we demonstrate a gut commensal protozoan-driven gut-lung axis that impacts the outcome or respiratory diseases.
December 19, 2024 at 9:30 PM
12) In summary, we demonstrate a gut commensal protozoan-driven gut-lung axis that impacts the outcome or respiratory diseases.
10) Can protozoan colonization be beneficial to respiratory bacterial infection? Eosinophils in the lungs of T.mu+ mice show greater degranulation following M.tb, infection, delaying the systemic dissemination of M.tb into the periphery, indicating respiratory shielding by a gut protozoan commensal.
December 19, 2024 at 9:30 PM
10) Can protozoan colonization be beneficial to respiratory bacterial infection? Eosinophils in the lungs of T.mu+ mice show greater degranulation following M.tb, infection, delaying the systemic dissemination of M.tb into the periphery, indicating respiratory shielding by a gut protozoan commensal.
9) When challenged, asthma manifests with a striking severity in animals colonized with T.mu. Interestingly, protozoa DNA traits are also found in patients with severe asthma, suggesting a disease exacerbating effect mediated by colonization with protozoa commensals.
December 19, 2024 at 9:30 PM
9) When challenged, asthma manifests with a striking severity in animals colonized with T.mu. Interestingly, protozoa DNA traits are also found in patients with severe asthma, suggesting a disease exacerbating effect mediated by colonization with protozoa commensals.
8) Which signals are needed to maintain this immune tripartite network? B cell-derived ICOSL OX40-OX40L interaction and T cell-derived IL-2 are critical to mediate iILC2 and eosinophil accumulation in response to intestinal protozoan colonization.
December 19, 2024 at 9:30 PM
8) Which signals are needed to maintain this immune tripartite network? B cell-derived ICOSL OX40-OX40L interaction and T cell-derived IL-2 are critical to mediate iILC2 and eosinophil accumulation in response to intestinal protozoan colonization.
7) We observed the accumulation of ILC2s with B cells and T cells in the lungs of T.mu colonized mice, suggesting a possible immune tripartite network upstream of airway eosinophilia.
December 19, 2024 at 9:30 PM
7) We observed the accumulation of ILC2s with B cells and T cells in the lungs of T.mu colonized mice, suggesting a possible immune tripartite network upstream of airway eosinophilia.
6) Surprisingly, T.mu-mediated iILC2 and eosinophilia in the lung require B and T cells. Only when protozoan commensal and iILC2, B cells and T cells come together is eosinophilia installed in the lung, suggesting an adaptive regulation of innate immune cells.
December 19, 2024 at 9:30 PM
6) Surprisingly, T.mu-mediated iILC2 and eosinophilia in the lung require B and T cells. Only when protozoan commensal and iILC2, B cells and T cells come together is eosinophilia installed in the lung, suggesting an adaptive regulation of innate immune cells.
4) iILC2s have been suggested to originate from the gut in response to IL-25. We used photo-conversion to formally demonstrate that gut-derived iILC2 accumulate in the lungs of T.mu colonized mice.
December 19, 2024 at 9:30 PM
4) iILC2s have been suggested to originate from the gut in response to IL-25. We used photo-conversion to formally demonstrate that gut-derived iILC2 accumulate in the lungs of T.mu colonized mice.
3) ILC2s are a major sources of IL-5 in the lung of T.mu+ mice, but here, ILC2s compose of natural ILC2 and inflammatory (i)ILC2s. iILC2s in the lungs of T.mu+ mice express high levels of IL-5, OX40L and ICOS implicating potential interactions with the adaptive immune system.
December 19, 2024 at 9:30 PM
2) T.mu promotes tuft cell-derived IL-25 explaining high IL-5 levels in the gut. However, alarmin production in the lung remained unchanged in the lung, despite high IL-5 production in this organ. Is the IL-5 source in the lung the same as in the gut?
December 19, 2024 at 9:30 PM
2) T.mu promotes tuft cell-derived IL-25 explaining high IL-5 levels in the gut. However, alarmin production in the lung remained unchanged in the lung, despite high IL-5 production in this organ. Is the IL-5 source in the lung the same as in the gut?
1) Animals colonized by the gut protozoa Tritrichomonas musculis (T.mu) show elevated numbers of bone marrow eosinophil precursors and eosinophils with higher expression of mucosal homing markers CCR3 and a4b7 integrin. Gut and lung eosinophils consequently elevate.
December 19, 2024 at 9:30 PM
1) Animals colonized by the gut protozoa Tritrichomonas musculis (T.mu) show elevated numbers of bone marrow eosinophil precursors and eosinophils with higher expression of mucosal homing markers CCR3 and a4b7 integrin. Gut and lung eosinophils consequently elevate.
Ever wondered how gut microbes control immune responses at extra-intestinal locations?
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...
December 19, 2024 at 9:30 PM
Ever wondered how gut microbes control immune responses at extra-intestinal locations?
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...
This platform keeps getting better and better! 😍🦋
The @preprintclub.bsky.social joined the bright side.
#immunosky
Share and follow for inter-institutional, trainee community reviews of preprint articles.
#preprints #openacess
www.preprintclub.com
The @preprintclub.bsky.social joined the bright side.
#immunosky
Share and follow for inter-institutional, trainee community reviews of preprint articles.
#preprints #openacess
www.preprintclub.com
December 10, 2024 at 3:10 PM
This platform keeps getting better and better! 😍🦋
The @preprintclub.bsky.social joined the bright side.
#immunosky
Share and follow for inter-institutional, trainee community reviews of preprint articles.
#preprints #openacess
www.preprintclub.com
The @preprintclub.bsky.social joined the bright side.
#immunosky
Share and follow for inter-institutional, trainee community reviews of preprint articles.
#preprints #openacess
www.preprintclub.com