Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...

say it again:

4 million people work in higher ed, the largest employer in 10 states, second largest employer in 10 more, and in 60 of the 100 biggest cities

ROI for NIH and NSF for local economies is conservatively 4x, often close to 10x

demolishing higher education is economic sabotage

#Immunology2025.

Obviously a timely topic! Can folks recommend articles or references on either public mistrust of science following the COVID pandemic and effect of recent EOs and administration change?

I have a guest lecture coming up in an Honors Colloquium for undergrads on Cancer and Society. Previously I focused on the history and mechanics for funding cancer research with a look at how public funds are appropriated, flow, and prioritized, compared to private $. What new articles should I use?

This new Atlantic piece on the timeline of the NIH shutdown reads like the script to a new Soderbergh film. It is so, so dark and perfectly captures the evil and intentional chaos behind everything we've experienced over the last month www.theatlantic.com/health/archi...

So much happening in the segmentation space for bioimage analysis. These two papers that were published online today really stood out to me as noteworthy (a thread).

(Sorry I took a brief timeout for uncontrollable weeping)

In other NIH news, I have heard from multiple sources that NIH plans to fire most, if not all, probationary employees this afternoon. The numbers I am hearing are >5000.

Lots of folks extramural staff, intramural scientists, etc.

Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.

globalnews.ca/news/9793403...

The average Fox News viewer has no idea that Musk is tearing down a system that allowed this country to rule the world for the past 75 years. And when their standard of living slips dramatically in the next five years they still won’t understand because their TV will blame it on some poor scapegoat.

Here is another one: go.bsky.app/JDAwbAJ

Let's share some other classic, the beautiful Cells in culture film directed by Michael Abercrombie one of the father of quantitative cell imaging (University College London, 1955) is available here identity.wellcomecollection.org/works/z6h7jzv4

I've been on here for 15 months, and the change over the last three weeks is truly stunning. Literally many thousands of new scientists on #SciSky. Community building is totally different here than the slow accretion method over years on Twitter. Here are a few thoughts from what I see. 1/n

go.bsky.app/JDAwbAJ Trying again with the actual link this time. Please tag yourself or others who study macropinocytosis, phagocytosis or efferocytosis, and I’ll add you to the pack!

Where are all the big drinkers🍺 and big eaters? I've created a starter pack to track down the #macropinocytosis, #phagocytosis, and #efferocytosis researchers on Bluesky. Who else is here? Please let me know and I'll add you/them! 🧪

I’d rather spend more time thinking about our screens, FP probes, and microscopy than Westerns. 😅 For those who grew up transferring on the Mini-protean system, have you switched your lab to another system and been happy with that choice? What are people mostly using these days?

I now have a student with color blindness in the lab and he keeps us in check. Things I’ve learned from him: red on black = no, pink and gray = no, blue and purple = no.

🔬 Are you eager to dive into the world of light microscopy & learn from top-notch microscopists about its essential techniques for life science applications? If that sounds exciting, don’t miss out on this free, in-depth iBiology series! 👉 www.ibiology.org/online-biolo...

Trying this out for #fluorescencefriday. 🧪 AktPH through an isosurface mesh of the plasma membrane. From this lattice lightsheet collaboration with @minesbioimaging.bsky.social: www.nature.com/articles/s41...

@minesbioimaging.bsky.social
@adhoppe.bsky.social

New paper out of the Thiex Lab! The moral of the story is think twice before you use dextran to study macropinocytosis! 😅 www.molbiolcell.org/doi/full/10....