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Mackenzie Weygandt Mathis @trackingactions.bsky.social · 1d

It’s going to be fabulous - I can’t wait! 🙌

Mackenzie Weygandt Mathis @trackingactions.bsky.social · 12d

Enjoying the extra flare in the office today courtesy of my lab ❤️🥹 - a little congrats that I gave my tenure talk yesterday! 🤞

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Reposted by Mackenzie Weygandt Mathis

mchurchland.bsky.social @mchurchland.bsky.social · Sep 8

Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric.
www.biorxiv.org/content/10.1...

Motor cortex flexibly deploys a high-dimensional repertoire of subskills

Skilled movement often requires flexibly combining multiple subskills, each requiring dedicated control strategies and underlying computations. How the motor system achieves such versatility remains u...

www.biorxiv.org

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Reposted by Mackenzie Weygandt Mathis

Kris Jensen @kristorpjensen.bsky.social · 14d

I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!

www.biorxiv.org/content/10.1...

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · 15d

Fall US trips booked! I'll be speaking at Scripps, SfN, and ICCV 🚀 Who will be at #ScrippsNeuroSymposium2025, #SfN2025 and/or #ICCV2025? Lots of ☀️🕶️🌴 & 🧠 in Oct/Nov!

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · 15d

Not just an amazing dataset, excellent 3D pose, shape, and eye tracking in the real world! Bravo @trackingskills.bsky.social et al!

PS - Exactly this kind of data we predict will be critical for long-term health monitoring @monosovlab.bsky.social et al: www.sciencedirect.com/science/arti...

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Reposted by Mackenzie Weygandt Mathis

The New Yorker @newyorker.com · 16d

A.I. tools are already shaping patient care—but we should be wary of letting them diagnose us. “Patients and doctors alike could think of A.I. not as a way to solve mysteries but as a way to gather clues,” Dhruv Khullar writes.

If A.I. Can Diagnose Patients, What Are Doctors For?

Large language models are transforming medicine—but the technology comes with side effects.

www.newyorker.com

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Reposted by Mackenzie Weygandt Mathis

Ardem Patapoutian @ardemp.bskyverified.social · 20d

New preprint alert! The uterus expands ~500-fold in pregnancy, yet we know little about how pressures are sensed. Led by @yunxiao-dr.bsky.social, we show PIEZOs are required for contractions and birth in mice, with dual roles of PIEZO1 in muscle and PIEZO2 in neurons
www.biorxiv.org/content/10.1...

PIEZO channels link mechanical forces to uterine contractions in parturition

Mechanical forces are extensively involved in pregnancy and parturition, but their precise roles and mechanisms remain poorly understood. Here, we identify mechanically activated ion channels PIEZO1 a...

www.biorxiv.org

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Reposted by Mackenzie Weygandt Mathis

Felix W. Moll @mollfw.bsky.social · 27d

DeepLabCut pose estimation (@trackingactions.bsky.social) revealed high intitial motor variability, which is essenatial for motor learning (Dhawale et al., 2017, Annu. Rev. Neurosci.).

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Sep 5

But yes, with our new mouse model, this is where we are going together 🦾🐭— looking for an ambitious PhD student!

Mouse model: www.biorxiv.org/content/10.1...

Neuro-musculoskeletal modeling reveals muscle-level neural dynamics of adaptive learning in sensorimotor cortex

The neural activity of the brain is intimately coupled to the dynamics of the body. In order to predict and adapt to the sensorimotor consequences of our actions, compelling behavioral studies in huma...

www.biorxiv.org

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Reposted by Mackenzie Weygandt Mathis

Kevin J. CREATURE @kevinjkircher.com · Sep 4

New paper in Nature finds that global geologic CO2 storage potential is ~90% lower than previously believed. Many candidate sites could leak CO2 back into the air or into groundwater, undermining climate mitigation efficacy or putting nearby human health at risk.

www.nature.com/articles/s41...

A prudent planetary limit for geologic carbon storage - Nature

A risk-based, spatially explicit analysis of carbon storage in sedimentary basins establishes a prudent planetary limit of around 1,460 Gt of geological carbon storage, which requires making explicit ...

www.nature.com

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Sep 4

I might be biased, but I think this is one of the most exciting developments in generalized musculoskeletal control in years ⬇️. Congrats to the team (I’m not involved!) 💪🔥

Alexander Mathis @trackingskills.bsky.social · Sep 4

Something exciting just left the gym -- meet Arnold the first generalist musculoskeletal control policy!

The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066

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Reposted by Mackenzie Weygandt Mathis

Alexander Mathis @trackingskills.bsky.social · Sep 4

Something exciting just left the gym -- meet Arnold the first generalist musculoskeletal control policy!

The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066

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Reposted by Mackenzie Weygandt Mathis

Venki Murthy @neurovenki.bsky.social · Sep 1

Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.

Mice navigate scent trails using predictive policies

Animals actively sense their environment to extract features of interest to guide behaviors. For mammals, odors are prominent environmental features which are sampled by active modulation of sniffing ...

www.biorxiv.org

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Reposted by Mackenzie Weygandt Mathis

EPFL School of Computer and Communication Sciences @icepfl.bsky.social · Sep 2

EPFL, ETH Zurich & CSCS just released Apertus, Switzerland’s first fully open-source large language model.
Trained on 15T tokens in 1,000+ languages, it’s built for transparency, responsibility & the public good.

Read more: actu.epfl.ch/news/apertus...

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Sep 2

This was a wonderful project to work on! It also, in part, sparked a lot!

Beyond just our handles: @trackingskills.bsky.social aka trackingplumes (Bluesky and X), when I wanted to track mouse hands & Alex noses, we teamed up in 2017 to make @deeplabcut.bsky.social 💜

Delighted to see this out! 🙏🏼

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Reposted by Mackenzie Weygandt Mathis

Ben Dichter @bendichter.com · Aug 25

Yes, AmadeusGPT is a great example of the kinds of structure that can make these LLMs truly useful for science

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Aug 25

Thanks Ben! 🙏🏼

Mackenzie Weygandt Mathis @trackingactions.bsky.social · Aug 25

* agentic system ^^ 🫣

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Aug 25

Selfishly, I’ll plug our tool LLM agent in system #AmadeusGPT - which lets you vibe code your behavioral analysis ;) and even gives you interpretable and verifiable outputs!

www.mackenziemathislab.org/amadeusgpt

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Aug 25

Check out the paper and code: arxiv.org/abs/2507.22813

github.com/AdaptiveMoto...

DISTIL: Data-Free Inversion of Suspicious Trojan Inputs via Latent Diffusion

Deep neural networks have demonstrated remarkable success across numerous tasks, yet they remain vulnerable to Trojan (backdoor) attacks, raising serious concerns about their safety in real-world miss...

arxiv.org

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Aug 25

This approach enhances the reliability of trigger reconstruction, making it capable of distinguishing between clean & trojaned models. 🚀

Congrats to all the authors who did an amazing job! 3/4

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Aug 25

By employing a diffusion-based generator guided by the target classifier, #DISTIL iteratively produces candidate triggers that align with the model's internal representations associated with malicious behavior. 2/4

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Mackenzie Weygandt Mathis @trackingactions.bsky.social · Aug 25

My lab has been pushing into explainable, robust, & theoretically-tractable AI models for science 💪

New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4

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Reposted by Mackenzie Weygandt Mathis

Paolo De Los Rios @paolodelosrios.bsky.social · Aug 21

A no-miss opportunity to join EPFL. We are a vibrant (had to use it 😉) community working in all branches of basic sciences and engineering, and interdisciplinary studies are strongly encouraged.
If you want more information, contact the committee heads, or feel free to DM me.

tinyurl.com/bd27ky7p

Assistant/associate Professor of AI-assisted Biophysics at the Ecole polytechnique fédérale de Lausanne (EPFL) and Group Leader at the Paul Scherrer Institute (PSI)

The School of Basic Sciences (Physics, Chemistry and Mathematics) at EPFL and the Paul Scherrer Institute (PSI) jointly seek to appoint a Tenure Track Assistant or tenured Associate Professor in AI-As...

tinyurl.com

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