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Thomas R. Cox

@trcox.matrixandmetastasis.com

2.4K followers 430 following 32 posts

Professor & Head of the Matrix & Metastasis Lab at the Garvan Institute of Medical Research & UNSW Sydney Gadigal Country 🇦🇺 🏳️‍🌈 🔬Pancreatic / Lung / Breast / Bowel Cancer & all things extracellular matrix 🧫 → https://linktr.ee/thomasrcox ←

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Thomas R. Cox @trcox.matrixandmetastasis.com · Nov 12

Ep4, S3 of the Garvan’s podcast: “Medical Minds” is out now!

I got the chance to talk about some of our labs ongoing work on fibrosis & cancer!

Why is it important? How does it feed into progression? And how does it affect treatment?

ow.ly/mnVs50TRiaQ

Available to stream on Apple & Spotify!

Reposted by Thomas R. Cox

Cancer Research UK Manchester Institute @cruk-mi.bsky.social · 2d

Interested in establishing your own research group?
Our support package for new Group Leaders includes:

🥼2 #Postdocs, a technician & 2 PhD students + lab costs
🔬Full access to core facilities
🧪Access to the MCRC #Biobank
✔️Mentorship, #grant advice & more

www.cruk.manchester.ac.uk/career/new-g...

Graphic has a blue-tone photograph of the Paterson Building on the right-hand side, with a dark blue background and white text on the left

Text says:

We Are Recruiting New Group Leaders
Join us in Manchester / Develop bold, innovative, & high-impact research programmes
Salary £58,000 – £65,000 (dependent upon experience/clinical work)
Job ID MI/25/54
Apply by 2nd November 2025

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Reposted by Thomas R. Cox

Shona Ritchie @shonaritchie.bsky.social · 2d

Had a fantastic time at @myueg.bsky.social week in Berlin, sharing science and meeting new colleagues/pals!

Huge thanks to @metastasisresearch.bsky.social for making it possible for me to attend and share our research

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Reposted by Thomas R. Cox

Metastasis Research Society @metastasisresearch.bsky.social · 20d

Attending a meeting? Early career MRS members can apply for a bursary! metastasis-research.org/for-research...
🚨Next bursary deadline is:October 1! 🚨

🎉 Congratulations again to our latest MRS Travel Bursary winners!

🌍 Shona Ritchie (Australia)
🇺🇸 Abby Jackson (USA)
🇮🇱 Avishai Maliah (Israel)

MRS Meeting Bursaries | Metastasis Research

The Metastasis Research Society is pleased to announce the availability of up to 10 Early Career Researcher (ECR) travel scholarships annually. These scholarships aim to support young investigators in presenting their metastasis research at national and international conferences.

metastasis-research.org

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Reposted by Thomas R. Cox

EACR - European Association for Cancer Research @helloeacr.bsky.social · 15d

As our Goodbye Flat Biology conference in Essen coincides with #WorldCancerResearchDay, what better way to mark the occasion than with a group photo? #WCRD @wcrd24sept.bsky.social

Group photo of a conference hall filled with participants posing in front of a World Cancer Research Day slide

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Reposted by Thomas R. Cox

Metastasis Research Society @metastasisresearch.bsky.social · 29d

Don't miss our next webinar by Zoi Diamantopoulou on "Timing the perfect strike: Using circadian rhythms to target metastasis" - September 22, 2025 - more details and register here: metastasis-research.org/2025/09/11/z...

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Reposted by Thomas R. Cox

Aguirre-Ghiso Lab @jaguirreghisolab.bsky.social · Sep 4

Pioneering trial targeting dormant residual cancer cells by L. Chodosh, A. DeMichele et al., @penncancer.bsky.social Proof-of-concept that targeting dormant RTCs in breast cancer survivors depletes MRD. NCT03032406. Congratulations for this work! www.nature.com/articles/s41...

Targeting dormant tumor cells to prevent recurrent breast cancer: a randomized phase 2 trial - Nature Medicine

A combination of mouse model data and data from a randomized phase 2 trial in patients with breast cancer in remission demonstrates feasibility, safety and a reduction in residual tumor cells followin...

www.nature.com

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Reposted by Thomas R. Cox

Matthia Karreman @matthiakarreman.bsky.social · Sep 4

How do #metastases survive (and thrive!) in the #brain microenvironment?

In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠

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Reposted by Thomas R. Cox

Metastasis Research Society @metastasisresearch.bsky.social · Aug 25

🚨Excited for the 2nd MRS Early Career Research Virtual Meeting on Nov 18-19, 2025!

Trainees & Junior Faculty (within 3 years of starting your lab), share your work!
Abstract Deadline: Sept 12, 2025. Submit here: bit.ly/47KLyp2

❗Free registration for MRS Members! #MRS #Research #EarlyCareer

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Thomas R. Cox @trcox.matrixandmetastasis.com · Aug 8

Congrats Emily!! 🎉

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Reposted by Thomas R. Cox

RedPen/BlackPen @redpenblackpen.bsky.social · Aug 8

Really just had something like this feeling this afternoon. It’s the high that keeps you coming back for more

Cartoon of a scientist peering through a microscope saying "Whoaah!!!". Title says "The best part of Science is knowing, for a moment, something that nobody else in the world knows."

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Reposted by Thomas R. Cox

Denis Wirtz @deniswirtz.bsky.social · Aug 8

The updated version of the database of PhD fellowships produced and maintained by my team can be downloaded by anyone here:

research.jhu.edu/rdt/funding-...

For each of the 187 fellowships, you will find a short description, deadline, $ amount, link, etc.

Good luck!

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Thomas R. Cox @trcox.matrixandmetastasis.com · Aug 8

@naxerova.bsky.social

Reposted by Thomas R. Cox

Metastasis Research Society @metastasisresearch.bsky.social · Aug 6

Calling all ECRs in cancer and metastasis research. Don't forget to register for the upcoming ECR Virtual Symposium in November (FREE for MRS members). More details here metastasis-research.org/2025/08/06/2...

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Reposted by Thomas R. Cox

Mathew Kiang @mathewkiang.com · Jun 25

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

Call for 20 Assistant Professor positions

Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

ki.se

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Reposted by Thomas R. Cox

Jon Humphries @jdhl18.bsky.social · Jun 27

Evolutionary paths towards metastasis
www.nature.com/articles/s41...

Evolutionary paths towards metastasis - Nature Reviews Cancer

In this Perspective, Kamila Naxerova discusses how genetic analyses of primary tumours and matched metastases can distinguish between competing metastasis evolution models, arguing that further insigh...

www.nature.com

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Reposted by Thomas R. Cox

Johanna Joyce @johannajoyce.bsky.social · Jun 27

🧠 Neuro-immunology is reshaping how we understand the brain - across many diseases, including #cancer

In this research highlight 🧪🔬 we discuss a new study in #Nature by Remsik, Boire et al showing how IFNγ-activated immune cells in the CNS, incl DCs, help constrain leptomeningeal #metastasis

CNS gatekeepers: IFNγ-activated dendritic cells control leptomeningeal metastasis - Cell Research

Cell Research - CNS gatekeepers: IFNγ-activated dendritic cells control leptomeningeal metastasis

www.nature.com

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Thomas R. Cox @trcox.matrixandmetastasis.com · Jun 28

Congrats! 🥳

Reposted by Thomas R. Cox

Nature Portfolio @natureportfolio.nature.com · Jun 28

Nature reports on how scientists are working to decipher the precise mechanisms that connect the brain to processes associated with ageing. #medsky 🧪

How your brain controls ageing — and why zombie cells could be key

Research is revealing the cellular mechanisms that link mental well-being and longevity.

go.nature.com

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Reposted by Thomas R. Cox

Metastasis Research Society @metastasisresearch.bsky.social · Jun 23

Register for our next ECLC webinar by Marco Montagner, PhD on Understanding the determinants of the invisible phase of metastasis - June 26th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - tinyurl.com/ujer8yw8

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Reposted by Thomas R. Cox

Guillaume Jacquemet @guijacquemet.bsky.social · Jun 23

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

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Reposted by Thomas R. Cox

Metastasis Research Society @metastasisresearch.bsky.social · Jun 17

1/Meet the MRS ECLC Chairs! Dr. Thomas Cox @trcox.matrixandmetastasis.com is a Professor at the @garvaninstitute.bsky.social focussing on the Extracellular Matrix and Fibrosis in Cancer.
We interviewed Dr. Cox about his role as a founding member of the MRS Early Career Leadership Council 🧵👇

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Reposted by Thomas R. Cox

OzMRS @ozmrs.bsky.social · Jun 12

Save the date! OzMRS Symposium 2025 will take place at the University of Wollongong on the 29th and 30th of October. More information coming soon. #Metastasis #CancerResearch

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Thomas R. Cox @trcox.matrixandmetastasis.com · Jun 11

New Review on Organ Repair & Fibrosis

Repeated organ injuries leads to abnormal ECM remodelling, disrupting tissue structure and function. Nice summary of the ECM's role in persistent fibrosis, organ-specific healing mechanisms, and anti-fibrotic strategies.

www.nature.com/articles/s44...

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Thomas R. Cox @trcox.matrixandmetastasis.com · Jun 3

New review paper written by Jess Chitty in the team just out in Trends in Cancer (@cp-trendscancer.bsky.social) (OpenAccess)
The extracellular matrix in cancer: from understanding to targeting
| → www.sciencedirect.com/science/arti... ← |

The extracellular matrix in cancer: from understanding to targeting

Significant advances in matrix biology research have enhanced our understanding of individual matrix components and extracellular matrix (ECM) signall…

www.sciencedirect.com

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Thomas R. Cox @trcox.matrixandmetastasis.com · Jun 3

June 4th = National Cheese Day 🧀 Sounds like a great excuse to eat one’s entire body weight in cheese 🤩 😋