Trevor Graham
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trevorgraham.bsky.social
Trevor Graham
@trevorgraham.bsky.social
Director, Centre for Evolution and Cancer @cec-icr.bsky.social at @icr.ac.uk

Genomics, epigenetics, evolution, mathematical modelling, data science, bowel cancer
Too kind Duncan, thank you.
January 19, 2026 at 9:29 AM
We focused the first #CANPOP on our local SE England community, but would be delighted to open it up nationally or even internationally for #CANPOP2.

Our goal is to help grow the cancer popgen community. Please do shout if you'd like to join us (also we're open to ideas of how to organise this too)
December 1, 2025 at 8:37 PM
Speakers were:
@carolinewatson.bsky.social (pre-leukaemia)
Verena Körber (Oxford) - SFS modelling
@calumgabbutt.bsky.social - methylation lineage tracing
@benjaminwerner.bsky.social - ecDNA evolution
@zaccasimo.bsky.social - CNA phylogenetics
Liz Murchison (Cambridge) - transmissible cancer
December 1, 2025 at 8:37 PM
Both projects involve lots of collaboration, supervision, mentorship and training (& travel!) across our @evomg-dn.bsky.social network. They mandate motility across the #EU and partner countries too. Consequently I think the studentships will offer exceptionally rich #PhD experiences.
October 14, 2025 at 8:30 PM
The second is about potential fitness costs of cancer drug resistance, and how we might exploit them using approaches like adaptive therapy. (building on our work with @mlockley.bsky.social in ovarian cancer: aacrjournals.org/cancerres/ar...). Description here: www.icr.ac.uk/study-and-ca...
Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control
Carboplatin adaptive therapy improves treatment efficacy without increasing daily dose due to reduced fitness of drug-resistant populations, which can be tracked using cfDNA and could direct adaptive ...
aacrjournals.org
October 14, 2025 at 8:26 PM
The first is about developing new approaches to track cancer evolution from cell free DNA (cfDNA - liquid biopsy), and is a collaboration with industry partner nonacus.com Description here: www.icr.ac.uk/study-and-ca...
October 14, 2025 at 8:23 PM