Thomas Oliver
@trwoliver.bsky.social
Academic pathologist (MD PhD) based in the UK.
Paediatric and Perinatal Pathology resident (Specialty Registrar), Addenbrooke's Hospital, Cambridge, UK.
Wellcome Sanger Institute, Hinxton, UK.
Paediatric and Perinatal Pathology resident (Specialty Registrar), Addenbrooke's Hospital, Cambridge, UK.
Wellcome Sanger Institute, Hinxton, UK.
Reposted by Thomas Oliver
Researchers develop AI tool that could speed up coeliac disease diagnosis - a study led by Professor Liz Soilleux finds algorithm is as effective as a pathologist in detecting the disease, and much quicker.
➡️ www.theguardian.com/science/2025...
➡️ www.theguardian.com/science/2025...
Researchers develop AI tool that could speed up coeliac disease diagnosis
Cambridge study finds algorithm is as effective as a pathologist in detecting disease – and much quicker
www.theguardian.com
March 27, 2025 at 3:48 PM
Researchers develop AI tool that could speed up coeliac disease diagnosis - a study led by Professor Liz Soilleux finds algorithm is as effective as a pathologist in detecting the disease, and much quicker.
➡️ www.theguardian.com/science/2025...
➡️ www.theguardian.com/science/2025...
Reposted by Thomas Oliver
Researchers have revealed a particular ‘rescue’ mutation that helps liver cells survive and outgrow damaged cells in alpha-1 antitrypsin deficiency, an inherited genetic condition. 🧬
The new study has promising implications for future therapies.
www.sanger.ac.uk/news_item/re...
The new study has promising implications for future therapies.
www.sanger.ac.uk/news_item/re...
‘Rescue’ mutations protect liver from damage in patients with genetic disorder
New research shows how mutations acquired throughout life can protect liver cells from damage caused by an inherited genetic condition.
www.sanger.ac.uk
March 10, 2025 at 5:17 PM
Researchers have revealed a particular ‘rescue’ mutation that helps liver cells survive and outgrow damaged cells in alpha-1 antitrypsin deficiency, an inherited genetic condition. 🧬
The new study has promising implications for future therapies.
www.sanger.ac.uk/news_item/re...
The new study has promising implications for future therapies.
www.sanger.ac.uk/news_item/re...
Reposted by Thomas Oliver
Read ‘Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1’ from @sangerinstitute.bsky.social, @greatormondst.bsky.social, @cuhnhs.bsky.social, and others in @naturegenet.bsky.social here ⤵️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1 - Nature Genetics
Histologically normal tissues of individuals with a germline NF1 mutation exhibited multiple second NF1 hits, unrelated to their tumors, that conferred a selective advantage.
www.nature.com
February 25, 2025 at 10:54 AM
Read ‘Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1’ from @sangerinstitute.bsky.social, @greatormondst.bsky.social, @cuhnhs.bsky.social, and others in @naturegenet.bsky.social here ⤵️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Oliver
Despite what was previously thought, genetic changes alone cannot explain why tumours grow in those with cancer predisposition condition, NF-1 🧬
New findings could help inform monitoring programmes for patients and possibly aid future treatments 🔎
www.sanger.ac.uk/news_item/re...
New findings could help inform monitoring programmes for patients and possibly aid future treatments 🔎
www.sanger.ac.uk/news_item/re...
Research challenges our understanding of cancer predisposition
New findings question assumptions of cancer formation in individuals with the cancer-predisposition syndrome, neurofibromatosis type 1, and offer hope for a personalised approach to early cancer recog...
www.sanger.ac.uk
February 25, 2025 at 10:54 AM
Despite what was previously thought, genetic changes alone cannot explain why tumours grow in those with cancer predisposition condition, NF-1 🧬
New findings could help inform monitoring programmes for patients and possibly aid future treatments 🔎
www.sanger.ac.uk/news_item/re...
New findings could help inform monitoring programmes for patients and possibly aid future treatments 🔎
www.sanger.ac.uk/news_item/re...