Thomas Oliver
trwoliver.bsky.social
Thomas Oliver
@trwoliver.bsky.social
Academic pathologist (MD PhD) based in the UK.
Paediatric and Perinatal Pathology resident (Specialty Registrar), Addenbrooke's Hospital, Cambridge, UK.
Wellcome Sanger Institute, Hinxton, UK.
Reposted by Thomas Oliver
Read ‘Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1’ from @sangerinstitute.bsky.social, @greatormondst.bsky.social, @cuhnhs.bsky.social, and others in @naturegenet.bsky.social here ⤵️

www.nature.com/articles/s41...
Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1 - Nature Genetics
Histologically normal tissues of individuals with a germline NF1 mutation exhibited multiple second NF1 hits, unrelated to their tumors, that conferred a selective advantage.
www.nature.com
February 25, 2025 at 10:54 AM