tspisak.bsky.social
@tspisak.bsky.social
190 followers 1.8K following 5 posts
Posts Media Videos Starter Packs
Pinned
tspisak.bsky.social
tspisak.bsky.social @tspisak.bsky.social · May 30
As many of you know, I’ve been fascinated by brain attractor dynamics lately.

Thrilled to share a new preprint on their link to orthogonal neural representations, co-authored with Karl Friston:
arxiv.org/abs/2505.22749
- with implications for both neuroscience & AI!

First in a series - stay tuned!
Self-orthogonalizing attractor neural networks emerging from the free energy principle
Attractor dynamics are a hallmark of many complex systems, including the brain. Understanding how such self-organizing dynamics emerge from first principles is crucial for advancing our understanding ...
arxiv.org
2 6 18
Reposted
olegolt.bsky.social
Ole Goltermann @olegolt.bsky.social · Jul 22
Serious concerns about a new cortical biomarker for pain sensitivity

jamanetwork.com/journals/jam...

We (with @tspisak.bsky.social, @christianbuchel.bsky.social) published a commentary on Chowdhury, Bi et al. (2025, JAMA Neurology) raising serious concerns about their reported results.

👇 1/13
Concern About Predictive Performance of a Pain Sensitivity Biomarker
To the Editor Chowdhury et al1 evaluated a biomarker for pain sensitivity, combining peak alpha frequency and corticomotor excitability. The authors report outstanding performance (validation set area...
jamanetwork.com
4 34 70
tspisak.bsky.social
tspisak.bsky.social @tspisak.bsky.social · May 30
@sfb-trr-289.bsky.social @karlfristonnews.bsky.social
2
tspisak.bsky.social
tspisak.bsky.social @tspisak.bsky.social · May 30
graphical abstract
tspisak.bsky.social
tspisak.bsky.social @tspisak.bsky.social · May 30
As many of you know, I’ve been fascinated by brain attractor dynamics lately.

Thrilled to share a new preprint on their link to orthogonal neural representations, co-authored with Karl Friston:
arxiv.org/abs/2505.22749
- with implications for both neuroscience & AI!

First in a series - stay tuned!
Self-orthogonalizing attractor neural networks emerging from the free energy principle
Attractor dynamics are a hallmark of many complex systems, including the brain. Understanding how such self-organizing dynamics emerge from first principles is crucial for advancing our understanding ...
arxiv.org
2 6 18
tspisak.bsky.social
tspisak.bsky.social @tspisak.bsky.social · May 28
@sfb-trr-289.bsky.social
2
tspisak.bsky.social
tspisak.bsky.social @tspisak.bsky.social · May 28
🚨 New paper out in GigaScience!
To avoid common pitfalls in multivariate modeling: combine external validation with pre-registration — freeze your model before testing.

For the pros: decide on the fly when to stop training!
First-authored by the brilliant @ggallitto.bsky.social
gigascience.bsky.social
GigaScience Journal @gigascience.bsky.social · May 28
A new approach for transparent reporting of prospective predictive modeling studies involving preregistration of machine learning models.

External validation of machine learning models—registered models and adaptive sample splitting doi.org/10.1093/giga...
External validation of machine learning models—registered models and adaptive sample splitting
AbstractBackground. Multivariate predictive models play a crucial role in enhancing our understanding of complex biological systems and in developing innov
doi.org
1 3 6