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Nico Dantuma @ubiquitinneuro.bsky.social · Sep 8

We are looking for a postdoc! Interested in protein degradation in cancer and neurodegeneration? Interested in the ubiquitin-proteasome system and autophagy? Application deadline Sept 26. #karolinskainstitutet #stockholm #postdocposition ki.varbi.com/en/what:job/...

Postdoctoral Researcher in Intracellular Protein Degradation in Cancer

Do you want to contribute to top quality medical research? The Dantuma lab at the Department of Cell and Molecular Biology has a long-standing interest in understanding the role of intracellular prote

ki.varbi.com

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Nico Dantuma @ubiquitinneuro.bsky.social · Jun 27

The Karolinska Institute announces 20 positions for Assistant Professors for outstanding early-career researchers. Positions include a startup package. Application deadline September 2nd. ki.varbi.com/en/what:job/...

Assistant Professor in Cell and Molecular Biology

Join a global community of excellence Karolinska Institutet, Department of Cell and Molecular Biology Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Insti

ki.varbi.com

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Nico Dantuma @ubiquitinneuro.bsky.social · Jun 27

The Karolinska Institute announces 20 positions for Assistant Professors in Biomedical Science for outstanding early-career researchers. Positions include a startup package. Application deadline September 2nd. ki.varbi.com/en/what:job/....

Assistant Professor in Biomedical Science

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,

ki.varbi.com

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Reposted by Nico Dantuma

ProteoCure @proteocure.bsky.social · May 24

Congrats to Corentin Bouvier, awardee of the FEBS Journal prize at the annual COST ProteoCure meeting. @costprogramme.bsky.social @febsj.bsky.social #ProteoCure2025

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Reposted by Nico Dantuma

ProteoCure @proteocure.bsky.social · May 24

Congrats to Mónica Pozo Rodriguez, awardee of the FEBS Open Bio Poster prize at the annual COST ProteoCure meeting. @costprogramme.bsky.social @febspress.bsky.social #ProteoCure2025

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Reposted by Nico Dantuma

ProteoCure @proteocure.bsky.social · May 24

Congrats to Simon Tack, awardee of the FEBS Journal Oral Presentation prize at the annual COST ProteoCure meeting.
@costprogramme.bsky.social @febsj.bsky.social
#ProteoCure2025

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Reposted by Nico Dantuma

ProteoCure @proteocure.bsky.social · May 21

An introduction into the role of mitochondrial dynamics in dealing with misfolded mitochondrial proteins by Luca Scorrano at the #ProteoCure2025 annual meeting. #COST

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Nico Dantuma @ubiquitinneuro.bsky.social · May 21

Michael Glickman presented his latest data on one of our favorite proteins UBB+1 and its role in Alzheimer's disease at the annual meeting of COST ProteoCure in Heraklion.

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Nico Dantuma @ubiquitinneuro.bsky.social · Mar 6

Mitochondria a safe haven for aggregation-prone proteins? #neurodegeneration. #Parkinson. Find our latest manuscript in @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

Mitochondria serve as a Holdout Compartment for Aggregation-Prone Proteins hindering Efficient Ubiquitin-Dependent Degradation

The accumulation of protein aggregates has been causatively linked to the pathogenesis of neurodegenerative diseases. In this study, we have conducted a genome-wide CRISPR-Cas9 screen to identify cell...

www.biorxiv.org

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Reposted by Nico Dantuma

Lisa Heinke @lisaheinke.bsky.social · Mar 6

Fantastic new paper out @nature.com! @merbllab.bsky.social discovers proteasome-derived peptides that function as a defence against bacterial infections. I'm not an immunologist but even I can tell that this finding has huge implications for new therapeutic interventions!

👉 go.nature.com/43k1a0H

Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature

Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...

www.nature.com

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Nico Dantuma @ubiquitinneuro.bsky.social · Feb 5

Today at 13:15 I will give a seminar at Uppsala Biomedical Centre entitled "Stimulating proteasomal degradation of neurodegeneration-associated proteins".

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Reposted by Nico Dantuma

Nature Chemical Biology @natchembio.nature.com · Jan 28

A Perspective from Xiaoyu Zhang, Gabriel Simon, and Benjamin Cravatt discusses recent strategies to expand the E3 ligase landscape and the scope of targeted protein
degradation

www.nature.com/articles/s41...

Implications of frequent hitter E3 ligases in targeted protein degradation screens - Nature Chemical Biology

This Perspective discusses recent strategies to expand the scope of targeted protein degradation (TPD) and the implications of unexpected convergence of diverse screening efforts on a small subset of ...

www.nature.com

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Reposted by Nico Dantuma

SFB Targeted Protein Degradation @sfb-tpd-vienna.bsky.social · Jan 27

Join us in Vienna 8-9 May for the #Ubiquitin & Friends Symposium 2025! Excellent line-up of guest speakers👇And many slots for talks from abstracts, plus flash-talks & posters! Lots of opportunities to network with peers & experts in a friendly atmosphere! ➡️ www.protein-degradation.org/symposium/

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Reposted by Nico Dantuma

Silvia Ramundo @sramundo.bsky.social · Jan 28

Looking forward to this year’s EMBO meeting about ESCRT proteins at the scenic Caux Palace, Montreux (CH) / To receive a notification when the website goes live, sign up here: coming-soon.embo.org/w25-75

ESCRT function, evolutionary diversity and mechanism of action

coming-soon.embo.org

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Reposted by Nico Dantuma

Max-Planck-Gesellschaft @maxplanck.de · Jan 23

More than 40 percent of #postdocs leave academia. Those who landed a coveted faculty position were more likely to have had a highly cited paper, changed their research topic between their #PhD and postdoc, or moved abroad after receiving their doctorate. www.pnas.org/doi/10.1073/... @pnas.org

More than 40% of postdocs leave academia, study reveals

Publishing highly cited papers helps postdoctoral researchers to land a faculty job.

www.nature.com

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Reposted by Nico Dantuma

Castañeda Lab at SU @castanedalab.bsky.social · Jan 6

Inspired by recent discoveries on ubiquitin-mediated condensates under physiological and stress conditions, we wrote this review on the intersection of protein quality control, phase separation, and function! #PQC #UPS #autophagy #ubiquitin #condensates

Trends in Biochemical Sciences @cp-trendsbiochem.bsky.social · Jan 6

Now online - the Review "Protein quality control machinery: regulators of condensate architecture and functionality" from Anitha Rajendran and Carlos @castanedalab.bsky.social.

#PQC #condensates #phaseseparation #chaperones #therapeutics

Access here 👉 authors.elsevier.com/a/1kNRo3S6Gf...

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Reposted by Nico Dantuma

Rune Busk Damgaard @rbdamgaard.bsky.social · Nov 15

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn

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Nico Dantuma @ubiquitinneuro.bsky.social · Jan 22

Good initiative. Can you put me on the list?

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Nico Dantuma @ubiquitinneuro.bsky.social · Jan 22

In our latest study, we report on how the SARS-CoV-2 protease PLpro manipulates autophagy. Paper in the Journal #Autophagy. #Covid, #Ubiquitin, #Proteasome. bit.ly/3E7cByg

Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugase

Viral proteases play critical roles in the host cell and immune remodeling that allows virus production. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) papain-like protease (PLpro...

bit.ly

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Nico Dantuma @ubiquitinneuro.bsky.social · Jan 22

I’ve just done my #eXit! the X exodus is massive. Don't lose any of your followers. Thanks to #HelloQuitX I've registered 1631 new passengers for a journey to #BlueSky & #Mastodon. Join us on app.helloquitx.com and automatically find your communities on #January20!

HelloQuitteX

Libérez vos espaces numériques

app.helloquitx.com

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