Umut Kilik
@umut-kilik.bsky.social
910 followers 990 following 10 posts
Postdoc @ FMI Basel (Turco Lab) | Exploring endometrium regeneration & niche 🌱🩸 | Human model systems + single-cell genomics + evo-devo | Former PhD @ IHB (Camp Lab)
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umut-kilik.bsky.social
🚨 After 7 years in the making, my PhD thesis work is finally published in @science.org 🧬✨
What does our gut say about how we became human? During my hitchhiking journey spanning 3 countries and multiple lab moves
graycamplab.bsky.social
Diet/microbes place the gut epithelium as a nexus for evolutionary change. With Jason Spence and Craig Lowe labs we use #organoids to explore how evolution prepared the developing human intestine for exposure to the environment. @science.org #evodevo www.science.org/doi/10.1126/... 1/11
Reposted by Umut Kilik
bacell3d.bsky.social
Join us on November 4th!
The winners of our best short talk awards will be telling their research on the @isscr.org stage!
Thank you @stemcellreports.bsky.social for co-organizing this webinar!
Reposted by Umut Kilik
mads100tist.bsky.social
This is it. The act of science -like art- is not the output, it is the interaction and the process. What makes us the kind of scientists we are is how we approach the problem 🧪
isabelott.bsky.social
It’s a common complaint to spend an afternoon reading papers in search of something that turns into half a sentence (that you delete next week) – I’d argue that the “foraging” benefits are real, only pay off if you’re engaging with the actual material, & worth the “inefficiency” to learn more.
Reposted by Umut Kilik
graycamplab.bsky.social
Final version @science.org "Recent evolution of the developing human intestine affects metabolic and barrier functions". Evolutionary preparation for microbiota, diet, and pathogen exposure is fascinating! Thank you @erc.europa.eu for supporting our vision!
www.science.org/doi/10.1126/...
Reposted by Umut Kilik
debbysilver.bsky.social
Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...
Reposted by Umut Kilik
graycamplab.bsky.social
Altogether, we identify the developing human intestinal epithelium as a rapidly evolving system, and show that great ape #organoids provide insight into human biology. 🙏Thanks 🙏 to all authors! Especially co-first authors: @CY_Qianhui_YU @KlkUmut @stefanosecchia 11/11
Reposted by Umut Kilik
graycamplab.bsky.social
Diet/microbes place the gut epithelium as a nexus for evolutionary change. With Jason Spence and Craig Lowe labs we use #organoids to explore how evolution prepared the developing human intestine for exposure to the environment. @science.org #evodevo www.science.org/doi/10.1126/... 1/11
umut-kilik.bsky.social
💡 What makes humans unique beyond our brains? Grateful for my PhD mentor @graycamplab.bsky.social and generous collaborators @Jason Spence, @Craig Lowe and @Barbara Treutlein and all their lab members made this work possible🙌 and @erc.europa.eu for funding this research!
umut-kilik.bsky.social
From Max-Planck-Institute for Evolutionary Anthropology to @eth-bsse.bsky.social to Institute of Molecular and Clinical Ophthalmology Basel (IOB) to @umich.edu to IHB, with brilliant co-first authors @Qianhui Yu & Stefano Secchia, we tackled
umut-kilik.bsky.social
🚨 After 7 years in the making, my PhD thesis work is finally published in @science.org 🧬✨
What does our gut say about how we became human? During my hitchhiking journey spanning 3 countries and multiple lab moves
graycamplab.bsky.social
Diet/microbes place the gut epithelium as a nexus for evolutionary change. With Jason Spence and Craig Lowe labs we use #organoids to explore how evolution prepared the developing human intestine for exposure to the environment. @science.org #evodevo www.science.org/doi/10.1126/... 1/11
Reposted by Umut Kilik
hsiuchuanlin.bsky.social
My postdoc work at Treutlein lab and @graycamplab.bsky.social with @jasperjanssens.bsky.social is out in @science.org ! We screen for neuron subtypes using pro-neural TFs + morphogen combinations + scRNA-seq and profiled over 700,000 cells in 480 conditions. www.science.org/doi/10.1126/...
umut-kilik.bsky.social
Thanks Maxime for the kind words🙂
Reposted by Umut Kilik
labwaggoner.bsky.social
Recent evolution of the developing human intestine affects metabolic and barrier functions @science.org @graycamplab.bsky.social
www.science.org/doi/10.1126/...
Reposted by Umut Kilik
biorxivpreprint.bsky.social
An organoid model of the menstrual cycle reveals the role of the luminal epithelium in regeneration of the human endometrium https://www.biorxiv.org/content/10.1101/2025.07.03.663000v1
Reposted by Umut Kilik
graycamplab.bsky.social
Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social@jasperjanssens.bsky.social‬ and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1
Reposted by Umut Kilik
mhr-reprodsci.bsky.social
✨Exciting news!✨
The World Endometriosis Research Foundation (#WERF) – Endometriosis Phenome and Biobanking Harmonisation Project (#EPHect) today publishes #SOPs to optimize the use of experimental in vivo and in vitro models in #endometriosis research.
Reposted by Umut Kilik
bacell3d.bsky.social
Katie Kubek from @novartis.bsky.social showed the work they have been doing with dog intestinal organoids 🐶 Exciting insights into serotonin signalling in mammals!
Reposted by Umut Kilik
ibidicells.bsky.social
🤩We had a fantastic time at #BaCell3D in Basel (June 23–25)! 🧬It was great to #exchange ideas on 3D cell culture, #organoids & in-vitro systems.

🤝Thanks to our Swiss #partner Vitaris AG – for joining us!🇨🇭

👋See you at the next #BaCell3D!

#organoids #BaCell3D #networking
Reposted by Umut Kilik
bacell3d.bsky.social
Highlights from our day1 conference dinner and networking event at the local favorite multi-cuisine bar and restaurant-Klara. Nerdy N2 B27 shots to welcome everyone , table soccer tournament, music and lots of discussions !
Reposted by Umut Kilik
christophertape.bsky.social
Incredibly impressed by the student/postdoc run @bacell3d.bsky.social conference. Great talks, a vibrant community, and so well organised 👏
Reposted by Umut Kilik
akanksha-jain.bsky.social
@sbwil91.bsky.social is our next speaker from Melissa Little’s group at the reNEW @novonordisk.bsky.social telling us about his work on multi lineage kidney assembloids
Reposted by Umut Kilik
bacell3d.bsky.social
Beautiful selected talk by Hao-An Hsiung from EPFL showing us human trunk assembloids with remarkable cell diversity, notochord and the gut tube!
Reposted by Umut Kilik
bacell3d.bsky.social
@maxmmahe.bsky.social Human intestinal organoids mature much faster when transplanted in vivo. Surprising discoveries on tubular organoids demonstrating higher cellular complexity!
Reposted by Umut Kilik
bacell3d.bsky.social
Amazing presentation by @mendjanlab.bsky.social explaining the potential of human cardioids. Increasing complexity step by step to generate more in vivo-like organoids!