Uri Alon
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urialonlab.bsky.social
Uri Alon
@urialonlab.bsky.social
The Alon lab explores design principles of biological circuits, focusing on systems medicine, aging, and healthspan.
Sweet moment in life, our 25th lab anniversary. In a circle, we looked at each other, a group of people with shared values and a soft approach, who want each other to succeed and be happy. (1/2)
April 23, 2025 at 12:07 PM
Masterpiece by a masterful scientist
Natural Neuroscience by Nachum Ulanovsky
@mitpress.bsky.social mitpress.mit.edu/978026204499...
April 16, 2025 at 8:07 AM
In pregnancies with complications (pre-eclampsia, gestational diabetes, postpartum hemorrhage),
distinct deviations from healthy profiles were evident. Gestational diabetes, in particular, showed marked changes, mostly in the pre-conception period.
March 27, 2025 at 12:44 PM
The study also spans 20 weeks pre-conception, where we see changes in folic acid, CRP, and albumin levels.
These hint lifestyle changes such as a healthier diet and taking recommended supplements, supporting healthy fetal development.
March 27, 2025 at 12:44 PM
Nearly half of the lab tests take many months (and in some cases up to a year) to settle after delivery,
highlighting what a journey pregnancy is, even after delivery.
March 27, 2025 at 12:44 PM
Lab tests can be clustered into stereotypical profiles, implying global control principles governing physiological adaptations in pregnancy.
We see strong undershoots and overshoots in many lab tests at delivery, indicating strong compensation mechanisms in action during pregnancy.
March 27, 2025 at 12:44 PM
Excited to share our new study revealing the intricate dynamics of pregnancy & postpartum physiology! We analyzed 40M lab tests from 300K pregnancies and 160K women (cross-sectional) and mapped week-by-week changes starting from preconception to months-long postpartum recovery.
March 27, 2025 at 12:44 PM
Sagol lecture in longevity research - Myriam Grunewald on vasculature maintenance for longevity
March 18, 2025 at 9:12 AM
Join us at the ICSB in Dublin this October - I will chair the session on aging systems biology
icsb2025.com
February 24, 2025 at 9:36 AM
Why do cortisol-lowering drugs work for Cushing’s but fail in mood disorders & chronic stress?
We propose that the ability of the pituitary and adrenal glands to adjust their functional masses—normally beneficial—counteracts the drug’s effect. Using a math. model, we screened HPA interventions (1/2)
February 4, 2025 at 3:53 PM
Excited to speak at the Global Conference on Gerophysics, where we'll explore how physics can revolutionize our understanding of aging and mortality. Join us and get 10% off registration with code GCGP10.
See you there, and sign up here: medicine.nus.edu.sg/trp/healthy-...
January 28, 2025 at 8:48 AM