Usman Tahir
@utahirmd.bsky.social
Director, Center for Cardiovascular Genetics | Beth Israel Deaconess Medical Center | Harvard Medical School | Precision Medicine & Omics
Reposted by Usman Tahir
Polygenic Prediction of Recurrent Events After Early-Onset Myocardial Infarction www.ahajournals.org/doi/10.1161/...
November 30, 2024 at 9:18 AM
Polygenic Prediction of Recurrent Events After Early-Onset Myocardial Infarction www.ahajournals.org/doi/10.1161/...
Reposted by Usman Tahir
Our preprint:
Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart
Multiomic atlas + human genetics = new cell types, genes, and pathways that influence heart development and disease
www.medrxiv.org/content/10.1...
Thread 👇
Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart
Multiomic atlas + human genetics = new cell types, genes, and pathways that influence heart development and disease
www.medrxiv.org/content/10.1...
Thread 👇
November 25, 2024 at 11:29 PM
Our preprint:
Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart
Multiomic atlas + human genetics = new cell types, genes, and pathways that influence heart development and disease
www.medrxiv.org/content/10.1...
Thread 👇
Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart
Multiomic atlas + human genetics = new cell types, genes, and pathways that influence heart development and disease
www.medrxiv.org/content/10.1...
Thread 👇
Reposted by Usman Tahir
Among British Pakistani & British Bangladeshi individuals, partitioned T2D polygenic load for insulin deficiency & lipodystrophy was higher than white European individuals & predisposed to faster progression to T2D & complications www.nature.com/articles/s41... @natureportfolio.bsky.social
November 26, 2024 at 2:04 PM
Among British Pakistani & British Bangladeshi individuals, partitioned T2D polygenic load for insulin deficiency & lipodystrophy was higher than white European individuals & predisposed to faster progression to T2D & complications www.nature.com/articles/s41... @natureportfolio.bsky.social
Reposted by Usman Tahir
Beats closest gene!
@jengreitz.bsky.social
@anshulkundaje.bsky.social
And others that I can't find on bluesky. But if you're here let me know so I can follow you!
@jengreitz.bsky.social
@anshulkundaje.bsky.social
And others that I can't find on bluesky. But if you're here let me know so I can follow you!
Mapping enhancer-gene regulatory interactions from single-cell data https://www.biorxiv.org/content/10.1101/2024.11.23.624931v1
Mapping enhancer-gene regulatory interactions from single-cell data https://www.biorxiv.org/content/10.1101/2024.11.23.624931v1
Mapping enhancers and their target genes in specific cell types is crucial for understanding gene re
www.biorxiv.org
November 25, 2024 at 12:23 AM
Beats closest gene!
@jengreitz.bsky.social
@anshulkundaje.bsky.social
And others that I can't find on bluesky. But if you're here let me know so I can follow you!
@jengreitz.bsky.social
@anshulkundaje.bsky.social
And others that I can't find on bluesky. But if you're here let me know so I can follow you!
Reposted by Usman Tahir
Atlas of the plasma proteome in health and disease in 53,026 adults 👩🔬🥼👨🔬🧪. #proteomics #proteome #plasma #MedSky 👇👇
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Atlas of the plasma proteome in health and disease in 53,026 adults
A large-scale proteomics study involving 53,026 individuals maps 2,920 plasma proteins
to 406 prevalent diseases, 660 incident diseases, and 986 health-related traits, identifying
promising biomarkers...
www.cell.com
November 23, 2024 at 7:49 AM
Atlas of the plasma proteome in health and disease in 53,026 adults 👩🔬🥼👨🔬🧪. #proteomics #proteome #plasma #MedSky 👇👇
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Usman Tahir
Excited to share this new Scientific Advisory doc from AHA on Gene Therapy for Cardiovascular Disease
A summary of mechanisms, delivery methods, future hurdles, and current trials (actually probably already out of date)
www.ahajournals.org/doi/10.1161/...
#AHA #CardioSky #cardiogen
A summary of mechanisms, delivery methods, future hurdles, and current trials (actually probably already out of date)
www.ahajournals.org/doi/10.1161/...
#AHA #CardioSky #cardiogen
November 12, 2024 at 8:41 PM
Excited to share this new Scientific Advisory doc from AHA on Gene Therapy for Cardiovascular Disease
A summary of mechanisms, delivery methods, future hurdles, and current trials (actually probably already out of date)
www.ahajournals.org/doi/10.1161/...
#AHA #CardioSky #cardiogen
A summary of mechanisms, delivery methods, future hurdles, and current trials (actually probably already out of date)
www.ahajournals.org/doi/10.1161/...
#AHA #CardioSky #cardiogen
Reposted by Usman Tahir
I did that starter pack thing for cardiovascular genetics #cardiogen and I’ll keep adding people as they join! Let me know if you’d like to be included go.bsky.app/4NjCKhB
November 9, 2024 at 9:37 PM
I did that starter pack thing for cardiovascular genetics #cardiogen and I’ll keep adding people as they join! Let me know if you’d like to be included go.bsky.app/4NjCKhB