Neural mechanisms underlying flexible learning and decision-making are not fully understood. Using single-cell calcium imaging, authors here found that neurons in orbitofrontal and secondary motor cortex exhibit complementary roles in reward learning, with neurons in the former exerting a sustained role in conditions of uncertainty.

Neuropsychopharmacology - Role of molecularly defined lateral septum cell types and circuits in social behaviors

How do humans and other animals make the decision to explore new options instead of exploiting familiar favorites? Hogeveen et al. find evidence for similar computations underlying explore-exploit dec...

Decisions are made with different degrees of consistency, and this consistency can be linked to the confidence that the best choice has been made. Theoretical work suggests that attractor dynamics in ...