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Alessio Quaresima

@bluedebris.bsky.social

180 followers 520 following 50 posts

Researcher in computational neuroscience. Interested in memory and perception! Working with a great team @BathellierLab, Institut de l'Audition, Paris. Personal page: https://aquaresima.github.io Julia Spiking Neural Networks: https://bit.ly/4mAbRly

aquaresima.github.io

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Alessio Quaresima @bluedebris.bsky.social · Mar 10

Are #Up-down states all about network dynamics?

In a recently revised preprint with @rcfduarte.bsky.social, H. Fritz, and P. Hagoort, we explore the role of nonlinear #dendrites as coincidence detectors and amplifiers of network fluctuations.

www.biorxiv.org/content/10.1...

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Alessio Quaresima @bluedebris.bsky.social · 1d

If you're still updating the starter pack, add me in ;)

Alessio Quaresima @bluedebris.bsky.social · 1d

I want to be the guy on the left. libera nos domine de AI

Alessio Quaresima @bluedebris.bsky.social · 1d

In the image I see a mid age person with a wise face and - probably - mastering a complex software Vs a youngster with a naive smile clicking buttons on an anonymous interface while the world burns

Alessio Quaresima @bluedebris.bsky.social · 2d

Then send a link to the blog ;)

Alessio Quaresima @bluedebris.bsky.social · 7d

At #BernsteinConference heated debate on WM mechanisms. I love that this is still far to be settled!

trained RNNs from A.Compte aligns with fruitfly direction WM data from K.Nagel: it is persistent.

Large scale recording in macaque V1 in T.Moore Lab: it is not.

#neuroskyence what's your take?

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Alessio Quaresima @bluedebris.bsky.social · 8d

And concluding with a beautiful thermodynamics of learning:

The correct learning rate depends on the noise of the training set (sigma eta)!

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Alessio Quaresima @bluedebris.bsky.social · 8d

And reminding the great neuroscientist **and middle east pacifist** Daniel Amit!

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Alessio Quaresima @bluedebris.bsky.social · 8d

So cool to walk from Ising models to recurrent network dynamics at the Braitenberg prize ceremony of Sara Solla! At #bernstein conference #compneurosky

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Alessio Quaresima @bluedebris.bsky.social · 12d

The library strikes a balance between creating new models and composing them in fairly complex networks.

If you would like some specific feat and cannot achieve it, just contact me and we'll find a way together!

Alessio Quaresima @bluedebris.bsky.social · 12d

Hey #neuroskyence and #compneurosky

I recently released this #Julia library for simulating Spiking
Neural Networks!

bit.ly/4mAbRly

As with everything in Julia, it is fast, elegant, and compact!
Check out the documentation and the tutorials to get an idea!

SpikingNeuralNetworks.jl Documentation · Julia SpikingNeuralNetworks

Documentation for Julia SpikingNeuralNetworks.

bit.ly

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Alessio Quaresima @bluedebris.bsky.social · 21d

Where do they get all this money to infest our market anyway???

Alessio Quaresima @bluedebris.bsky.social · 22d

And yess! The students loved it :)

Alessio Quaresima @bluedebris.bsky.social · 24d

Hey #neuroskyence #compneurosky

I made this interactive tool for showing the phase planes of 2D neuron models to studs!

Have fun :)

github.com/JuliaSNN/Com...

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Alessio Quaresima @bluedebris.bsky.social · 26d

Thank you! I wanted to feel better this mornin 🤣

Reposted by Alessio Quaresima

PessoaBrain @pessoabrain.bsky.social · 29d

𝗕𝗿𝗮𝗶𝗻-𝘄𝗶𝗱𝗲 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀
Spatially distributed and regionally unbound cellular resolution brain-wide processing loops in mice
𝗕𝗿𝗮𝗶𝗻 𝗿𝗲𝗴𝗶𝗼𝗻𝘀 𝗼𝗿 𝗱𝘆𝗻𝗮𝗺𝗶𝗰 𝘁𝗵𝗿𝗲𝗮𝗱𝘀?
Dynamical processing winding through most brain regions.
Looks like a must read.
www.biorxiv.org/content/10.1...
#neuroskyence

Spatially distributed and regionally unbound cellular resolution brain-wide processing loops in mice

Until recently, it has been possible to examine activity in the brain globally through regional averaging or locally at cellular resolution. These studies characterized regions as functionally homogen...

www.biorxiv.org

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Reposted by Alessio Quaresima

Nature Portfolio @natureportfolio.nature.com · 29d

The International Brain Laboratory presents in Nature a brain-wide electrophysiological map that represents a resource for understanding how computations distributed across and within brain areas drive behaviour. go.nature.com/4nnnmhg 🧪 🧠📈

This is figure 2, which shows brain-wide recordings during behaviour.

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Reposted by Alessio Quaresima

Neurofrontiers @neuro-frontiers.bsky.social · Aug 22

Progesterone is another sex hormone best known for its effects on the female reproductive system. Similar to estrogens, however, it’s becoming increasingly clearer that progesterone impacts many more systems in the body, both in females and in males.

#neuroskyence #skyence #hormones

Progesterone in the brain - Neurofrontiers

Progesterone is a sex hormone with broad effects beyond the reproductive system, in particular in the brain.

neurofrontiers.blog

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Alessio Quaresima @bluedebris.bsky.social · Aug 21

Will this be online?

Alessio Quaresima @bluedebris.bsky.social · Jul 15

There are examples of different IPSP dependently on the location of the afferent on the postsynaptic neuron. That would do?

Alessio Quaresima @bluedebris.bsky.social · Jul 5

I don't understand, whats the problem if people use chatgpt to write part of their text?

Like, the write the prompt with the info in bullet points, and ask for a text. Is this any type of scientific fraud?

Alessio Quaresima @bluedebris.bsky.social · Jul 4

What a time when you could title your paper like this!

Alessio Quaresima @bluedebris.bsky.social · Jul 4

@imbizo.bsky.social

Hey! Great school!

Are teaching assistants applications still open?

Reposted by Alessio Quaresima

Max Planck Institute for Psycholinguistics @mpi-nl.bsky.social · Jun 30

Nonlinear dendritic integration supports Up-Down states in single neurons. Paper by @bluedebris.bsky.social & al. With Hartmut Fitz, Peter Hagoort
doi.org/10.1523/JNEUROSCI.1701-24.2025
Paper: tinyurl.com/34pptvv5

Nonlinear Dendritic Integration Supports Up–Down States in Single Neurons

Changes in the activity profile of cortical neurons are due to effects at the scale of local and long-range networks. Accordingly, abrupt transitions in the state of cortical neurons—a phenomenon know...

doi.org

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Reposted by Alessio Quaresima

James Vornov @jjvornov.bsky.social · Jun 24

The neuroscience tale of how purple, really magenta, is a synthetic color not found on the spectrum. We don't perceive the environment, but become aware of the brain's processing of color. I conclude, Kant was right, there is a priori knowledge. But he never realized it was neuronal.

#neuroskyence

If Purple isn’t real, then what is?

Let’s talk epistemology. Actually, let’s have magenta and cyan bid farewell to epistemology altogether

open.substack.com

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Alessio Quaresima @bluedebris.bsky.social · Jun 22