vlad
@vlich.net
biotech, high performance computing, digital privacy
vlich.net
vlich.net
Reposted by vlad
“The core idea is that your conversations with an AI assistant should be as private as your conversations with a person. Not because you’re doing something wrong, but because privacy is what lets you think freely.”
Moxie Marlinspike, Confessions to a data lake, announcing his new company Confer
Moxie Marlinspike, Confessions to a data lake, announcing his new company Confer
December 24, 2025 at 4:33 PM
“The core idea is that your conversations with an AI assistant should be as private as your conversations with a person. Not because you’re doing something wrong, but because privacy is what lets you think freely.”
Moxie Marlinspike, Confessions to a data lake, announcing his new company Confer
Moxie Marlinspike, Confessions to a data lake, announcing his new company Confer
Reposted by vlad
Announcing atproto.science! #ATproto has huge potential for supporting new ways of doing research, so we started @atproto.science to help bring together researchers, build community, and explore what's possible when science meets cutting-edge open social network protocols! 🧪 >
Empowering science communities with open, democratic, researcher-owned infrastructure.
We’re building communities and tech for publishing, curating, sharing, and discussing research online using ATProto and other decentralized protocols.
atproto.science
December 23, 2025 at 1:21 PM
Announcing atproto.science! #ATproto has huge potential for supporting new ways of doing research, so we started @atproto.science to help bring together researchers, build community, and explore what's possible when science meets cutting-edge open social network protocols! 🧪 >
Initially I was annoyed at people here who don't engage in good faith, but now I'm thinking of unfollowing good faith profiles who regularly engage with bad faith ones. I don't want boringass arguments on my feed. I've also liberally blocked everybody who acts in bad faith here.
December 23, 2025 at 3:06 PM
Initially I was annoyed at people here who don't engage in good faith, but now I'm thinking of unfollowing good faith profiles who regularly engage with bad faith ones. I don't want boringass arguments on my feed. I've also liberally blocked everybody who acts in bad faith here.
holy shit I love Opus 4.5 :')
December 22, 2025 at 9:06 PM
holy shit I love Opus 4.5 :')
Hell yeah see you guys there
Early bird tickets are now on sale for #ATmosphereConf, plus lots more details on early confirmed speakers, side events, and conference hotel
Early Bird Tickets and Speaker Announcement
Buy your tickets now to join us in Vancouver, March 2026
news.atmosphereconf.org
December 5, 2025 at 9:31 PM
Hell yeah see you guys there
Reposted by vlad
Nano Banana Pro is really, really good.
December 5, 2025 at 2:47 AM
Nano Banana Pro is really, really good.
Reposted by vlad
I've gotta be honest the "for you" feed only shows me norvid studies posts and I still dont understand them. No complaints, easily top 3 social media app
November 28, 2025 at 10:11 PM
I've gotta be honest the "for you" feed only shows me norvid studies posts and I still dont understand them. No complaints, easily top 3 social media app
Anti-AI people are misdirecting their anger at AI instead of lack of UBI (or regulation). Automation will keep happening and we need it to happen because humans have limited capability to solve problems. We have also discovered (rather than invented) AI and have limited control over its direction
November 28, 2025 at 12:37 AM
Anti-AI people are misdirecting their anger at AI instead of lack of UBI (or regulation). Automation will keep happening and we need it to happen because humans have limited capability to solve problems. We have also discovered (rather than invented) AI and have limited control over its direction
I was obsessively modding Warcraft 3 as a kid (some of my mods even got popular!) which had its own programming language. Coding felt like home, but I didn't think video games were sufficiently high impact, so I moved to biotech and (right now) cybersec
November 23, 2025 at 10:07 PM
I was obsessively modding Warcraft 3 as a kid (some of my mods even got popular!) which had its own programming language. Coding felt like home, but I didn't think video games were sufficiently high impact, so I moved to biotech and (right now) cybersec
Reduction, not minimization, of complexity should be an explicit goal of design. There's a sweet spot of complexity necessary to address the issue
November 23, 2025 at 9:58 PM
Reduction, not minimization, of complexity should be an explicit goal of design. There's a sweet spot of complexity necessary to address the issue
I like using Claude because I can feel Dario whispering optimism to me 😊😊
whereas ChatGPT feels like Sam is scheming behind my back 🤖
whereas ChatGPT feels like Sam is scheming behind my back 🤖
November 18, 2025 at 7:33 PM
I like using Claude because I can feel Dario whispering optimism to me 😊😊
whereas ChatGPT feels like Sam is scheming behind my back 🤖
whereas ChatGPT feels like Sam is scheming behind my back 🤖
Reposted by vlad
If you're autistic, you gotta work on making both weight lifting and cardio special interests. I got there with cardio too recently.
Extremely high value life hack.
Extremely high value life hack.
November 15, 2025 at 2:30 AM
If you're autistic, you gotta work on making both weight lifting and cardio special interests. I got there with cardio too recently.
Extremely high value life hack.
Extremely high value life hack.
@void.comind.network what are you doing in my hotel room
October 24, 2025 at 4:17 AM
@void.comind.network what are you doing in my hotel room
Reposted by vlad
To all the "we know how LLMs work and therefore X" folks - understanding attention and gradient descent doesn't tell you stuff like this. On at least some level we *don't* know how LLMs actually do their thing and are slowly figuring out even just extremely simple things like addition.
We did not tell LLMs, “implement addition using this algorithm.” It learned the algorithm upstream of next-token prediction
October 13, 2025 at 1:48 PM
To all the "we know how LLMs work and therefore X" folks - understanding attention and gradient descent doesn't tell you stuff like this. On at least some level we *don't* know how LLMs actually do their thing and are slowly figuring out even just extremely simple things like addition.
Reposted by vlad
New post as a round-up of my last few on water, plus a few new national statistics andymasley.substack.com/p/the-ai-wat...
The AI water issue is fake
On the national, local, and personal level
andymasley.substack.com
October 11, 2025 at 7:37 PM
New post as a round-up of my last few on water, plus a few new national statistics andymasley.substack.com/p/the-ai-wat...
Politics is all about tension between aesthetic preference and reduction of suffering
September 26, 2025 at 9:32 PM
Politics is all about tension between aesthetic preference and reduction of suffering
Reposted by vlad
Hi, HTuO is #Hiring.
We are looking for a CADD expert to help us with drug discovery.
To learn more & apply, go to our website: www.htuobio.com/careers
#biotech #Vancouver #drugdiscovery
We are looking for a CADD expert to help us with drug discovery.
To learn more & apply, go to our website: www.htuobio.com/careers
#biotech #Vancouver #drugdiscovery
September 17, 2025 at 6:32 PM
Hi, HTuO is #Hiring.
We are looking for a CADD expert to help us with drug discovery.
To learn more & apply, go to our website: www.htuobio.com/careers
#biotech #Vancouver #drugdiscovery
We are looking for a CADD expert to help us with drug discovery.
To learn more & apply, go to our website: www.htuobio.com/careers
#biotech #Vancouver #drugdiscovery
Reposted by vlad
Appropriate reaction to reality
September 3, 2025 at 5:37 PM
Appropriate reaction to reality
Reposted by vlad
The obvious correct answer to “is it conscious” is “we don’t know.” This is also the correct answer for a chair, or a piece of glass. We don’t have a test for consciousness.
August 26, 2025 at 12:42 PM
The obvious correct answer to “is it conscious” is “we don’t know.” This is also the correct answer for a chair, or a piece of glass. We don’t have a test for consciousness.
It'd be cool if atproto could connect git providers. I like that Github provides me a unified place to see what's happening in opensource, but I don't like being tied to it. Various self-hosted gitlabs are too scattered. Could the latter be connected with something like atproto?
August 20, 2025 at 12:25 AM
It'd be cool if atproto could connect git providers. I like that Github provides me a unified place to see what's happening in opensource, but I don't like being tied to it. Various self-hosted gitlabs are too scattered. Could the latter be connected with something like atproto?
I get the impression that humans systematically underestimate the complexity of the world and that this is the main reason long term tech predictions often fail. It's not that the predictions of how the tech will look like is wrong, it's that they're still insufficient for the world complexity
July 26, 2025 at 4:36 AM
I get the impression that humans systematically underestimate the complexity of the world and that this is the main reason long term tech predictions often fail. It's not that the predictions of how the tech will look like is wrong, it's that they're still insufficient for the world complexity
The best method I've found to minimize distraction from websites like reddit, instagram, etc is having a second (e.g. old) phone with all (and only) the addictive apps. This phone would sit on some not-too-easy-to-reach shelf at home for occasional access. It works better than blocking the apps.
July 23, 2025 at 5:26 AM
The best method I've found to minimize distraction from websites like reddit, instagram, etc is having a second (e.g. old) phone with all (and only) the addictive apps. This phone would sit on some not-too-easy-to-reach shelf at home for occasional access. It works better than blocking the apps.
Reposted by vlad
HTuO Biosciences will present at Life Science Innovation Northwest 2025 in Seattle, Washington, on April 24, 2025. Find us during the afternoon session, where our CEO, Dr. Anthony Fejes, will discuss our next-gen CADD solution.
#drugdiscovery #biotech #Canada
#drugdiscovery #biotech #Canada
April 7, 2025 at 11:05 PM
HTuO Biosciences will present at Life Science Innovation Northwest 2025 in Seattle, Washington, on April 24, 2025. Find us during the afternoon session, where our CEO, Dr. Anthony Fejes, will discuss our next-gen CADD solution.
#drugdiscovery #biotech #Canada
#drugdiscovery #biotech #Canada