Vivien Shek
@vshek.bsky.social
86 followers
140 following
7 posts
Decoding immune responses to S. mansoni in the MacDonald lab 🪱🔬📊
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Vivien Shek
@vshek.bsky.social
· May 23
Henry McSorley
@henrymcsorley.bsky.social
· May 22
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
The murine intestinal nematode Heligmosomoides polygyrus bakeri (Hpb) modulates the host immune response via the Hpb alarmin release inhibitor (HpARI)…
www.sciencedirect.com
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Cell Reports
@cp-cellreports.bsky.social
· May 21
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
The helminth immunomodulators from the HpARI and HpBARI families can block IL-33 responses. Smyth and Hodge et al. show that vaccination with these immunomodulatory proteins can raise blocking antibody responses against them, allowing the development of effective anti-parasite type 2 immunity and ejection of the parasite.
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Henry McSorley
@henrymcsorley.bsky.social
· Dec 12
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