Andrew Maclean
@macleanlab.bsky.social
MRC research fellow at the University of Edinburgh working on parasite metabolism.
Reposted by Andrew Maclean
There's still time to register for CoccidiaUK in London - it's going to be a jam-packed two days of talks by early-career parasitologists, a knowledge transfer session, plus trivia and prizes! It's @crick.ac.uk (very central) & we're cooking up some fun swag :) www.eventbrite.co.uk/e/coccidiauk...
CoccidiaUK 2025
A biannual gathering of parasitologists from across the UK to discuss all things coccidian!
www.eventbrite.co.uk
November 26, 2025 at 5:15 PM
There's still time to register for CoccidiaUK in London - it's going to be a jam-packed two days of talks by early-career parasitologists, a knowledge transfer session, plus trivia and prizes! It's @crick.ac.uk (very central) & we're cooking up some fun swag :) www.eventbrite.co.uk/e/coccidiauk...
Reposted by Andrew Maclean
Looking to start a PhD in October 2026 and learn about bioinformatics and the regulation of TGF-beta signalling in macrophages?
Check out this PhD opportunity with a multidisciplinary team at the University of Edinburgh: www.findaphd.com/phds/project...
Check out this PhD opportunity with a multidisciplinary team at the University of Edinburgh: www.findaphd.com/phds/project...
Precision Medicine DTP - Towards precision therapeutics for macrophages: developing a multi-organ understanding of macrophage control by TGF-β at University of Edinburgh on FindAPhD.com
PhD Project - Precision Medicine DTP - Towards precision therapeutics for macrophages: developing a multi-organ understanding of macrophage control by TGF-β at University of Edinburgh, listed on ...
www.findaphd.com
November 24, 2025 at 12:15 PM
Looking to start a PhD in October 2026 and learn about bioinformatics and the regulation of TGF-beta signalling in macrophages?
Check out this PhD opportunity with a multidisciplinary team at the University of Edinburgh: www.findaphd.com/phds/project...
Check out this PhD opportunity with a multidisciplinary team at the University of Edinburgh: www.findaphd.com/phds/project...
Reposted by Andrew Maclean
Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...
November 11, 2025 at 9:26 AM
Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...
Reposted by Andrew Maclean
Coming up: Postdoctoral fellowship mini-workshop as a part of the SPPIRIT Forum series. EMBO, Marie Curie, and Wellcome Early Career fellows will share their advice on fellowship applications.
Join us at 12 noon on Thursday 14th November!
Register at docs.google.com/forms/d/e/1F...
Join us at 12 noon on Thursday 14th November!
Register at docs.google.com/forms/d/e/1F...
November 4, 2025 at 11:45 AM
Coming up: Postdoctoral fellowship mini-workshop as a part of the SPPIRIT Forum series. EMBO, Marie Curie, and Wellcome Early Career fellows will share their advice on fellowship applications.
Join us at 12 noon on Thursday 14th November!
Register at docs.google.com/forms/d/e/1F...
Join us at 12 noon on Thursday 14th November!
Register at docs.google.com/forms/d/e/1F...
Reposted by Andrew Maclean
If you’re interested in solving bacterial mysteries, this PhD project is for you!
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Investigating the role of the Vi antigen in Salmonella pathogenesis. at University of Edinburgh on FindAPhD.com
PhD Project - Investigating the role of the Vi antigen in Salmonella pathogenesis. at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
November 2, 2025 at 6:07 PM
If you’re interested in solving bacterial mysteries, this PhD project is for you!
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Andrew Maclean
Incredibly proud to share that our work on Cryptosporidium Oocyst Wall Proteins is published in
@PLOSPathogens
journals.plos.org/plospathogen...
Led by previous PhD student
@BacchettiRoss
and carried on by current PhD student, Sarah Stevens.
@PLOSPathogens
journals.plos.org/plospathogen...
Led by previous PhD student
@BacchettiRoss
and carried on by current PhD student, Sarah Stevens.
Cryptosporidium oocyst wall proteins are true components of the oocyst wall and COWP8 is not required for parasite transmission
Author summary Infection with Cryptosporidium causes diarrhoea, which can be fatal for malnourished children or people who are immunocompromised. There is no vaccine or effective medicines available t...
journals.plos.org
October 23, 2025 at 6:40 PM
Incredibly proud to share that our work on Cryptosporidium Oocyst Wall Proteins is published in
@PLOSPathogens
journals.plos.org/plospathogen...
Led by previous PhD student
@BacchettiRoss
and carried on by current PhD student, Sarah Stevens.
@PLOSPathogens
journals.plos.org/plospathogen...
Led by previous PhD student
@BacchettiRoss
and carried on by current PhD student, Sarah Stevens.
Reposted by Andrew Maclean
Learn how our hunt for the native structure of top antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms.nature.com 👉 rdcu.be/eLRlH 🦠🔬❄️
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
Endogenous structure of antimalarial target PfATP4 reveals an apicomplexan-specific P-type ATPase modulator
Nature Communications - Here, the authors present the 3.7 Å cryoEM structure of native sodium efflux pump PfATP4 from Plasmodium falciparum, revealing a bound protein that they term...
rdcu.be
October 20, 2025 at 12:55 PM
Learn how our hunt for the native structure of top antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms.nature.com 👉 rdcu.be/eLRlH 🦠🔬❄️
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
Reposted by Andrew Maclean
Excited to share our new paper!
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Tepsin and AP4 mediate transport from the trans-#Golgi to the plant-like vacuole in #toxoplasma, say Janessa Grech, Elena Jiménez-Ruiz @jimenezruizlab.bsky.social, Markus Meissner @meissnerlab.bsky.social & colleagues @lmumuenchen.bsky.social: rupress.org/jcb/article/...
#Microbiology #Cytoskeleton
#Microbiology #Cytoskeleton
October 20, 2025 at 1:36 PM
Excited to share our new paper!
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Reposted by Andrew Maclean
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (elxw.fa.em3.oraclecloud.com/hcmUI/Candid...). Find out more about us in the link below.
The Matthews Lab | Biology
The Matthews Lab
biology.ed.ac.uk
October 17, 2025 at 12:06 PM
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (elxw.fa.em3.oraclecloud.com/hcmUI/Candid...). Find out more about us in the link below.
Reposted by Andrew Maclean
Delighted to share this story from my PhD! 🎉 🪱
Latest McSorley lab paper is out! Led by Vivien @vshek.bsky.social, this is a story about the immunomodulators from H. polygyrus bakeri (Hpb), and how their analysis led to the identification of HpBoRB, a secreted protein which binds host RELM-beta www.sciencedirect.com/science/arti...
September 29, 2025 at 7:36 AM
Delighted to share this story from my PhD! 🎉 🪱
Reposted by Andrew Maclean
From nutrient acquisition to drug resistance, membrane transport is especially important for intracellular parasites! This review will help you stay up-to-date on the latest transport research for crypto/malaria/toxo: www.sciencedirect.com/science/arti...
September 26, 2025 at 9:34 AM
From nutrient acquisition to drug resistance, membrane transport is especially important for intracellular parasites! This review will help you stay up-to-date on the latest transport research for crypto/malaria/toxo: www.sciencedirect.com/science/arti...
Reposted by Andrew Maclean
Latest McSorley lab paper is out! Led by Vivien @vshek.bsky.social, this is a story about the immunomodulators from H. polygyrus bakeri (Hpb), and how their analysis led to the identification of HpBoRB, a secreted protein which binds host RELM-beta www.sciencedirect.com/science/arti...
September 25, 2025 at 7:28 AM
Latest McSorley lab paper is out! Led by Vivien @vshek.bsky.social, this is a story about the immunomodulators from H. polygyrus bakeri (Hpb), and how their analysis led to the identification of HpBoRB, a secreted protein which binds host RELM-beta www.sciencedirect.com/science/arti...
Reposted by Andrew Maclean
[We are Hiring!]
The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM.
This project aims to unlock new strategies for treating toxoplasmosis.
DM for more info!
The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM.
This project aims to unlock new strategies for treating toxoplasmosis.
DM for more info!
September 19, 2025 at 4:28 PM
[We are Hiring!]
The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM.
This project aims to unlock new strategies for treating toxoplasmosis.
DM for more info!
The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM.
This project aims to unlock new strategies for treating toxoplasmosis.
DM for more info!
Reposted by Andrew Maclean
The Plant Shape Lab is hiring! Are you interested in supporting cutting edge cereal research? We are looking for an enthusiastic and dedicated technician to join us for 2 years, setting up and running cereal transformation. Find out more, and apply here: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
September 22, 2025 at 7:33 AM
The Plant Shape Lab is hiring! Are you interested in supporting cutting edge cereal research? We are looking for an enthusiastic and dedicated technician to join us for 2 years, setting up and running cereal transformation. Find out more, and apply here: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Reposted by Andrew Maclean
📢 7 weeks to go until our SPPIRIT symposium
A fantastic opportunity for ECR parasitologists across Scotland to network and showcase their research.
🗓️ 31 October 2025 | 📍 Roslin Institute, Edinburgh
🎟️ Free to attend → tinyurl.com/3yzjnm5h
Secure your spot today!
A fantastic opportunity for ECR parasitologists across Scotland to network and showcase their research.
🗓️ 31 October 2025 | 📍 Roslin Institute, Edinburgh
🎟️ Free to attend → tinyurl.com/3yzjnm5h
Secure your spot today!
Hostbusters: SPPIRITed to Roslin
Bringing together ECR parasitologists from across Scotland to network and showcase their science.
tinyurl.com
September 12, 2025 at 6:31 PM
📢 7 weeks to go until our SPPIRIT symposium
A fantastic opportunity for ECR parasitologists across Scotland to network and showcase their research.
🗓️ 31 October 2025 | 📍 Roslin Institute, Edinburgh
🎟️ Free to attend → tinyurl.com/3yzjnm5h
Secure your spot today!
A fantastic opportunity for ECR parasitologists across Scotland to network and showcase their research.
🗓️ 31 October 2025 | 📍 Roslin Institute, Edinburgh
🎟️ Free to attend → tinyurl.com/3yzjnm5h
Secure your spot today!
Reposted by Andrew Maclean
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
September 11, 2025 at 11:09 AM
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Reposted by Andrew Maclean
Don't miss the chance to learn from an industry expert in drug discovery and connect with the Tryps Club community! 🌍✨
Join us for the first Career Talk of the 2025–2026 Tryps Club season!
Prof. Paul M. Selzer will give us an insight into anti-parasitic drug development in industry.
📅 Date: 24.09.2025
🕒 Time: 12:00 pm BST
📍 Location: Zoom
Register following link or the QR code on the poster
lnkd.in/eA7b9QRx
Prof. Paul M. Selzer will give us an insight into anti-parasitic drug development in industry.
📅 Date: 24.09.2025
🕒 Time: 12:00 pm BST
📍 Location: Zoom
Register following link or the QR code on the poster
lnkd.in/eA7b9QRx
September 11, 2025 at 6:38 AM
Don't miss the chance to learn from an industry expert in drug discovery and connect with the Tryps Club community! 🌍✨
Reposted by Andrew Maclean
The trypanosomal TAC is required for mitochondrial DNA segregation. We provide insight into TAC assembly: one of the most extreme sorting event for any mitochondrion.
Congratulations to Philip, Salome and Bernd
#mitochondria #mtDNA #Trypanosoma
journals.plos.org/plospathogen...
Congratulations to Philip, Salome and Bernd
#mitochondria #mtDNA #Trypanosoma
journals.plos.org/plospathogen...
Assembly of the mitochondrial outer membrane module of the trypanosomal tripartite attachment complex
Author summary Mitochondria are essential for nearly all eukaryotes. This requires proper segregation of the organelles and their genomes to the daughter cells during cell division. For Trypanosomes a...
journals.plos.org
September 10, 2025 at 6:57 AM
The trypanosomal TAC is required for mitochondrial DNA segregation. We provide insight into TAC assembly: one of the most extreme sorting event for any mitochondrion.
Congratulations to Philip, Salome and Bernd
#mitochondria #mtDNA #Trypanosoma
journals.plos.org/plospathogen...
Congratulations to Philip, Salome and Bernd
#mitochondria #mtDNA #Trypanosoma
journals.plos.org/plospathogen...
Reposted by Andrew Maclean
SULSA is running an Industry Academia conference on 28th & 29th October.
Looks fantastic for researchers working in Scotland- particularly good for students interested in learning more about industry & working on skill development!
sulsa.ac.uk/indac/
Looks fantastic for researchers working in Scotland- particularly good for students interested in learning more about industry & working on skill development!
sulsa.ac.uk/indac/
IndAc Conference - SULSA
sulsa.ac.uk
August 26, 2025 at 2:02 PM
SULSA is running an Industry Academia conference on 28th & 29th October.
Looks fantastic for researchers working in Scotland- particularly good for students interested in learning more about industry & working on skill development!
sulsa.ac.uk/indac/
Looks fantastic for researchers working in Scotland- particularly good for students interested in learning more about industry & working on skill development!
sulsa.ac.uk/indac/
Reposted by Andrew Maclean
Now available in a polished format! An important step toward accelerated functional genomics for the Cryptosporidium parasite. Brought to you by the incomparable @lucy-watson.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestine - Nature Communications
Cryptosporidium is an important threat to public health, yet it lacks a robust genetic toolkit. Here, Watson et al. introduce a targeted CRISPR-based screening method to identify parasite genes that a...
www.nature.com
August 20, 2025 at 5:58 PM
Now available in a polished format! An important step toward accelerated functional genomics for the Cryptosporidium parasite. Brought to you by the incomparable @lucy-watson.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Andrew Maclean
Only one week left until SPPIRIT Forum meeting! Join us to discuss recent work on mosquito tissue ultrastructure-expansion microscopy for malaria research, and ask questions to the 1st author, @benliffner.bsky.social, who will join us!
For meeting link fill in: tinyurl.com/3j5ewezv
For meeting link fill in: tinyurl.com/3j5ewezv
August 15, 2025 at 4:21 PM
Only one week left until SPPIRIT Forum meeting! Join us to discuss recent work on mosquito tissue ultrastructure-expansion microscopy for malaria research, and ask questions to the 1st author, @benliffner.bsky.social, who will join us!
For meeting link fill in: tinyurl.com/3j5ewezv
For meeting link fill in: tinyurl.com/3j5ewezv
Reposted by Andrew Maclean
🚨NEW PAPER🚨 We've already shown mosquito infections vary by time-of-day, here we test whether infection of mice FROM mosquitoes vary in a rhythmic manner. We test this in untreated & drug treated mice as some fitness consequences are only apparent in stressful environments doi.org/10.1186/s130...
August 15, 2025 at 1:09 PM
🚨NEW PAPER🚨 We've already shown mosquito infections vary by time-of-day, here we test whether infection of mice FROM mosquitoes vary in a rhythmic manner. We test this in untreated & drug treated mice as some fitness consequences are only apparent in stressful environments doi.org/10.1186/s130...
Reposted by Andrew Maclean
We’re pleased to share our new study, led by @jezieldamasceno.bsky.social, that used long-read, single molecule sequencing to reveal the full (?) picture of Leishmania DNA replication. Thanks, Mike Boemo and helpful reviewers @uofgsii.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Leishmania major chromosomes are replicated from a single high-efficiency locus supplemented by thousands of lower efficiency initiation events
DNA replication initiates at genome sites termed origins. Previous origin mapping approaches in the populations of the protozoan parasite Leishmania m…
www.sciencedirect.com
August 15, 2025 at 7:32 AM
We’re pleased to share our new study, led by @jezieldamasceno.bsky.social, that used long-read, single molecule sequencing to reveal the full (?) picture of Leishmania DNA replication. Thanks, Mike Boemo and helpful reviewers @uofgsii.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Andrew Maclean
I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
We are looking for a talented and enthusiastic postdoctoral researcher to join the Shaw lab to investigate identify the regulatory function of NRROS/LRRC33 in gastrointestinal macrophage development a...
elxw.fa.em3.oraclecloud.com
August 12, 2025 at 2:56 PM
I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...