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Journal of Cell Biology

@jcb.org

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Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press @rupress.org 🌐 https://rupress.org/jcb

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Journal of Cell Biology @jcb.org · Sep 3

Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...

#Reproducibility

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Reposted by Journal of Cell Biology

Tim @timisstuck.bsky.social · 15h

Thrilled to see this out !! More cell biology of immune cells please!

Congrats to @mmorrissey.bsky.social and @kirstin-rollins.bsky.social 🥳

Journal of Cell Biology @jcb.org · 16h

Target cell adhesion limits macrophage #phagocytosis and promotes #trogocytosis, say @kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al.
@ucsantabarbara.bsky.social rupress.org/jcb/article/...

#Macrophages #Immunology

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Journal of Cell Biology @jcb.org · 14h

Spotlight: Anant Menon @weillcornell.bsky.social discusses recent advances by Li, Suzuki et al. (rupress.org/jcb/article/...), identifying a DLO-pyrophosphatase (Llp1), which maintains DLO quality control in eukaryotes. rupress.org/jcb/article/...

#Biochemistry #lipid #Organelles #Glycosylation

Journal of Cell Biology @jcb.org · 15h

Hongli Li, Marc Fransen et al. identify PEX14 as a key link between optineurin and the autophagic machinery in #pexophagy, the selective degradation of #peroxisomes. This discovery advances our understanding of #peroxisome clearance and disease. rupress.org/jcb/article/...

#Autophagy #Organelles

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Reposted by Journal of Cell Biology

Maik Bischoff @maikbischoff.bsky.social · 16d

1/12 A very special moment for me! 🎉

My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.

rupress.org/jcb/article/...

#cellbio #devbio #science

🧵for details

Cartoon of a speculative heterogenous cell population performing mesenchymal collective cell migration.

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Reposted by Journal of Cell Biology

Christophe 🔬 L @christlet.bsky.social · 15d

Beautiful live-cell imaging of lysosome tubulation along microtubules in this work just out from @lysoluis.bsky.social et al:
rupress.org/jcb/article/...

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Journal of Cell Biology @jcb.org · 16h

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Reposted by Journal of Cell Biology

Manuel Thery @manuelthery.bsky.social · 3d

What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social

rupress.org/jcb/article-...

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Journal of Cell Biology @jcb.org · 1d

Magliozzi, Goode and colleagues @brandeisuniversity.bsky.social report that fungal proteins form a 'composite' #actin nucleator and pointed end capper. rupress.org/jcb/article/...

#Cytoskeleton #Biochemistry

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Journal of Cell Biology @jcb.org · 2d

New study from Swift, Pustova, Audhya et al. @uwmadison.bsky.social defines the native dynamics of the ESCRT-III component Ist1 in mammalian cells, highlighting the existence of multiple, unique pools at #endosomes. rupress.org/jcb/article/...

#membrane #lipid

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Journal of Cell Biology @jcb.org · 2d

📣 Don't miss the October 17 deadline! Apply for JCB’s Alan Hall & Norton B. Gilula Travel Awards that support #undergraduates, #gradstudents, and early-career #postdocs to attend #cellbio2025 ✈️ 👉 rupress.org/jcb/pages/al...

Journal of Cell Biology @jcb.org · 3d

SCFFBXO21-mediated ubiquitination and degradation of NMNAT2 regulates axon survival in nerve injury, say Wenjing Long, Yanshan Fang et al.

#Ubiquitin #Neuroscience

Journal of Cell Biology @jcb.org · 4d

Our October issue is out! rupress.org/jcb/issue/22...
The cover shows early postnatal mouse cortex w/ #astrocytes (magenta) & their #mitochondria (green) in a model of inhibited astrocytic mitochondrial fission. See Rodriguez Salazar, @caglaeroglu.bsky.social et al rupress.org/jcb/article/...

Journal of Cell Biology @jcb.org · 4d

LLP1 is a pyrophosphatase involved in homeostasis/quality control of dolichol-linked oligosaccharide, say Sheng-Tao Li, Tadashi Suzuki and colleagues: rupress.org/jcb/article/...

Reposted by Journal of Cell Biology

Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 6d

Previously unknown contacts between mitochondria identified using new approach with AI & volumetric electron microscopy

📹 Benjamin S. Padman, Runa S.J. Lindblom & @lazaroulab.bsky.social, @monashuniversity.bsky.social @jcb.org

➡️ bpod.org.uk/archive/2025/10/3 with
@antdlewis.bsky.social

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Journal of Cell Biology @jcb.org · 7d

@kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al show that #macrophages attack adherent cells using #trogocytosis instead of #phagocytosis. Reducing adhesion increased phagocytosis. Mitotic cells, which disassemble adhesions, are more vulnerable to phagocytosis rupress.org/jcb/article/...

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Journal of Cell Biology @jcb.org · 8d

Join @jcb.org Scientific Editor Gabriele Stephan at the EMBO | EMBL Symposium “Cell biology of the nucleus” during the lunchtime Meet the Editor talk Nov. 19. www.embl.org/about/info/c... #EESNucleus @events.embl.org

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Reposted by Journal of Cell Biology

Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 9d

Lipid transporter BLTP2 recruitment to ER-plasma membrane contacts controls membrane dynamics

📷 @anbangdai.bsky.social et al @yaleschoolofmed.bsky.social
in @jcb.org

➡️ bpod.org.uk/archive/2025...

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Journal of Cell Biology @jcb.org · 9d

JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation, say Luis Bonet-Ponce @lysoluis.bsky.social, Mark R. Cookson @markrcookson.bsky.social and colleagues rupress.org/jcb/article/...

#Organelles #Lysosomes #Trafficking

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Journal of Cell Biology @jcb.org · 9d

Vacuolar pH regulates #clathrin-mediated #endocytosis through #TORC1 signaling during replicative #aging, say Kenneth Gabriel Antenor, Mojca Mattiazzi Usaj et al. @torontometsci.bsky.social rupress.org/jcb/article/...

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Journal of Cell Biology @jcb.org · 10d

Wenjing Long, Yanshan Fang et al reveal that an SCFFBXO21 E3 #ubiquitin ligase complex ubiquitinates NMNAT2 at K155 & promotes its turnover in neurons & show that Fbxo21 deficiency confers axonal protection both in vitro & in vivo rupress.org/jcb/article/...
#Neuroscience

Journal of Cell Biology @jcb.org · 10d

Patterning in motion: Cell interfaces guide mesenchymal collective migration and #morphogenesis. A new perspective from @maikbischoff.bsky.social & @mayorlab.bsky.social rupress.org/jcb/article/...

#CellBio #CellMigration #Development #Science

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Journal of Cell Biology @jcb.org · 10d

All roads lead to TDP43: Convergent mechanisms of TDP43 autoregulation. Morgan Miller & Sami Barmada highlight recent work from Hasegawa-Ogawa and colleagues (rupress.org/jcb/article/...):

rupress.org/jcb/article/...

#Neuroscience #RNAbiology #Neurodegeneration

Journal of Cell Biology @jcb.org · 10d

Galectin-9 regulates #DendriticCell polarity and uropod contraction by modulating RhoA activity, say Guus Franken, Laia Querol Cano et al. rupress.org/jcb/article/...

#CellMigration #Immunology #Immunotherapy

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Journal of Cell Biology @jcb.org · 11d

Dolichol-linked oligosaccharide (DLO) is the precursor for asparagine-linked protein #glycosylation. Sheng-Tao Li, Tadashi Suzuki et al. identify a DLO-pyrophosphatase (Llp1), which is involved in DLO homeostasis/quality control. rupress.org/jcb/article/...

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Journal of Cell Biology @jcb.org · 11d

This collection features tools for rapid vimentin perturbation, studies of single vimentin intermediate filaments, and new findings on the nuclear lamina incl. its interactions w/ telomeres in germ cells or disruptions in the nuclear lamina caused by nuclear aggregates rupress.org/jcb/collecti...

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