Ist2 is a #phospholipid scramblase that links #lipid transport at the ER to organelle homeostasis, say Heitor Gobbi Sebinelli, Camille Syska, Hafez Razmazma, Luca Monticelli, Guillaume Lenoir, Alenka Čopič @umontpellier.bsky.social et al: rupress.org/jcb/article/...

#Biophysics #ER_literature

Atypical E-#cadherin attachments mediate melanoblast migration through confined epithelial spaces, say Denay J.K. Richards, Danelle Devenport and colleagues @princetonmolbio.bsky.social: rupress.org/jcb/article/...

#Adhesion #Development #Migration #motility

#Collagen IV intercellular concentrations mediate cell–cell #adhesion in the #Drosophila #adipose tissue. New study from Almasoud, Franz et al. @ucl-cdb.bsky.social finds that the adipose tissue has apical-basal cell #polarity, which regulates this adhesion. rupress.org/jcb/article/...

Lund et al. @ucph.bsky.social reveal that coupling of neuropeptide-containing dense core vesicles undergoing axonal transport to #kinesin-1 & #dynein is mediated by an adaptor complex composed of Syd/dJIP3/4 and RUFY, controlled by Rab2, Arl8, & the Arl8 activator BORC. rupress.org/jcb/article/...