Bungo Akiyoshi
@bungoakiyoshi.bsky.social
Studying kinetochores in African trypanosome (kinetoplastid) and marine plankton (diplonemid) in Edinburgh
https://www.ed.ac.uk/biology/groups/akiyoshi
https://www.ed.ac.uk/biology/groups/akiyoshi
Pinned
My attempt to become a professor was unsuccessful again but the diplonema tagging paper is now published in Open Biology. royalsocietypublishing.org/doi/10.1098/...
Reposted by Bungo Akiyoshi
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵
#protistsonsky 🧵
November 25, 2025 at 8:41 PM
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵
#protistsonsky 🧵
Reposted by Bungo Akiyoshi
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 25, 2025 at 12:16 PM
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Bungo Akiyoshi
I however wonder why a new supergroup was erected (Disparia) when the existing supergroup Promethea precisely describes this grouping? Promethea was published here: www.cell.com/iscience/ful...
Phylogenetic position and mitochondrial genome evolution of “orphan” eukaryotic lineages
Evolutionary biology; Phylogenetics
www.cell.com
November 21, 2025 at 9:30 AM
I however wonder why a new supergroup was erected (Disparia) when the existing supergroup Promethea precisely describes this grouping? Promethea was published here: www.cell.com/iscience/ful...
Reposted by Bungo Akiyoshi
Why IDPs Are Poor Candidates for Homotypic LLPS
🧵👇A thread
🧵👇A thread
November 20, 2025 at 6:32 PM
Why IDPs Are Poor Candidates for Homotypic LLPS
🧵👇A thread
🧵👇A thread
Reposted by Bungo Akiyoshi
Why LLPS Scaffolds Cannot Exist – A Thermodynamic Thread
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
November 19, 2025 at 5:48 AM
Why LLPS Scaffolds Cannot Exist – A Thermodynamic Thread
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
Trypanosoma
First we traced the evolutionary history of AMT1 (aka MTA1), the main 6mA enzyme in eukaryotes. We find that a complex repertoire including AMT1 and its heterodimeric partner AMT6/7 can be traced back to the Last Eukaryotic Common Ancestor. Same goes for the RNA methyltransferases METTL3/14. 2/9
November 18, 2025 at 1:22 PM
Trypanosoma
Reposted by Bungo Akiyoshi
Post 1
As noted yesterday: the in-vitro assay in the 2016 @cp-cell.bsky.social Cell paper from @brangwynnelab.bsky.social (dx.doi.org/10.1016/j.cell.2016.04.047) led to wrong conclusions about NPM1 LLPS in nucleolar assembly.
(see image)
As noted yesterday: the in-vitro assay in the 2016 @cp-cell.bsky.social Cell paper from @brangwynnelab.bsky.social (dx.doi.org/10.1016/j.cell.2016.04.047) led to wrong conclusions about NPM1 LLPS in nucleolar assembly.
(see image)
November 18, 2025 at 7:22 AM
Post 1
As noted yesterday: the in-vitro assay in the 2016 @cp-cell.bsky.social Cell paper from @brangwynnelab.bsky.social (dx.doi.org/10.1016/j.cell.2016.04.047) led to wrong conclusions about NPM1 LLPS in nucleolar assembly.
(see image)
As noted yesterday: the in-vitro assay in the 2016 @cp-cell.bsky.social Cell paper from @brangwynnelab.bsky.social (dx.doi.org/10.1016/j.cell.2016.04.047) led to wrong conclusions about NPM1 LLPS in nucleolar assembly.
(see image)
Reposted by Bungo Akiyoshi
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Write a letter of support to help keep Jalview funded!
Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...
discourse.jalview.org
November 17, 2025 at 10:25 PM
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Write a letter of support to help keep Jalview funded!
Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...
discourse.jalview.org
November 17, 2025 at 9:55 PM
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Reposted by Bungo Akiyoshi
1/ It is no secret that I view the unchecked rise of liquid–liquid phase separation (LLPS) in biology as a profound distortion of molecular biology. It conflicts with its principles, it is logically incompatible with them, and the claims made in its name have been, with rare exceptions,...
–>2
–>2
November 14, 2025 at 8:27 AM
1/ It is no secret that I view the unchecked rise of liquid–liquid phase separation (LLPS) in biology as a profound distortion of molecular biology. It conflicts with its principles, it is logically incompatible with them, and the claims made in its name have been, with rare exceptions,...
–>2
–>2
Reposted by Bungo Akiyoshi
Radiolarian - a huge one!
November 15, 2025 at 10:47 PM
Radiolarian - a huge one!
Reposted by Bungo Akiyoshi
It’s a beautiful afternoon. Dive 3 (864). We are taking Subastian into a deep underwater canyon. Live feed will begin soon: www.youtube.com/@SchmidtOcea...
November 15, 2025 at 8:53 PM
It’s a beautiful afternoon. Dive 3 (864). We are taking Subastian into a deep underwater canyon. Live feed will begin soon: www.youtube.com/@SchmidtOcea...
Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...
November 11, 2025 at 9:26 AM
Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...
Reposted by Bungo Akiyoshi
November 10, 2025 at 2:29 PM
Simply looking at the 60 pages of images is just so much fun. Data S1 console.s3.embl.de/browser/cult...
November 10, 2025 at 2:19 PM
Simply looking at the 60 pages of images is just so much fun. Data S1 console.s3.embl.de/browser/cult...
Reposted by Bungo Akiyoshi
Only the second radiolarian I’ve seen in my life, and this one is a chonks!
#marineplankton #protistsonsky 🦑
#marineplankton #protistsonsky 🦑
November 6, 2025 at 8:26 PM
Only the second radiolarian I’ve seen in my life, and this one is a chonks!
#marineplankton #protistsonsky 🦑
#marineplankton #protistsonsky 🦑
I was happy with the cell counter which worked for more than 10 years. When I bought a new one recently, the company sent a newer version, which turned out to be an absolute nightmare
October 31, 2025 at 9:50 AM
I was happy with the cell counter which worked for more than 10 years. When I bought a new one recently, the company sent a newer version, which turned out to be an absolute nightmare
Reposted by Bungo Akiyoshi
Béla Novák (1956–2025) – a legacy of scientific discovery and personal charm
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
October 17, 2025 at 2:02 PM
Béla Novák (1956–2025) – a legacy of scientific discovery and personal charm
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
Reposted by Bungo Akiyoshi
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (elxw.fa.em3.oraclecloud.com/hcmUI/Candid...). Find out more about us in the link below.
The Matthews Lab | Biology
The Matthews Lab
biology.ed.ac.uk
October 17, 2025 at 12:06 PM
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (elxw.fa.em3.oraclecloud.com/hcmUI/Candid...). Find out more about us in the link below.
Reposted by Bungo Akiyoshi
HHMI adopts Plan U journals.plos.org/plosbiology/...
September 24, 2025 at 6:08 PM
HHMI adopts Plan U journals.plos.org/plosbiology/...
Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes
September 19, 2025 at 11:22 AM
Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes
Reposted by Bungo Akiyoshi
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
September 11, 2025 at 11:09 AM
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Reposted by Bungo Akiyoshi
A big welcome to everyone who has joined us for the @bspparasitology.bsky.social trypanosomiasis and leishmaniasis meeting this week in the beautiful city of Ceske Budějovice!
September 1, 2025 at 8:19 PM
A big welcome to everyone who has joined us for the @bspparasitology.bsky.social trypanosomiasis and leishmaniasis meeting this week in the beautiful city of Ceske Budějovice!
I guess I have been quite open about my ongoing diplonema project, showing PCR results, live cell imaging, IF attempts, some interesting localization. For example, my tweet about "one of two flagella" protein led to conversations with various people I had not talked to. It's been so much fun
If you're in academia or industry and have taken action to push the needle to make your research, science, data etc. more open and useful (even if you've been told it will damage your career or goals), I'd love to know about what you've done.
2/4
2/4
August 13, 2025 at 8:25 PM
I guess I have been quite open about my ongoing diplonema project, showing PCR results, live cell imaging, IF attempts, some interesting localization. For example, my tweet about "one of two flagella" protein led to conversations with various people I had not talked to. It's been so much fun
Core funding, Orbitrap Astral, Aquilos 2, super low facility charges, etc etc
August 13, 2025 at 6:33 PM
Core funding, Orbitrap Astral, Aquilos 2, super low facility charges, etc etc