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Bungo Akiyoshi

@bungoakiyoshi.bsky.social

1.4K followers 540 following 230 posts

Studying kinetochores in African trypanosome (kinetoplastid) and marine plankton (diplonemid) in Edinburgh https://www.ed.ac.uk/biology/groups/akiyoshi

www.ed.ac.uk

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 6

My attempt to become a professor was unsuccessful again but the diplonema tagging paper is now published in Open Biology. royalsocietypublishing.org/doi/10.1098/...

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Reposted by Bungo Akiyoshi

Richard Sever @richardsever.bsky.social · 14d

HHMI adopts Plan U journals.plos.org/plosbiology/...

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · 19d

Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes

First author of the paper Lim along with his PhD advisor. Congrats both!

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Reposted by Bungo Akiyoshi

Dr Joanne Power @hanniepower.bsky.social · 27d

Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟

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Reposted by Bungo Akiyoshi

British Society for Parasitology @bspparasitology.bsky.social · Sep 1

A big welcome to everyone who has joined us for the @bspparasitology.bsky.social trypanosomiasis and leishmaniasis meeting this week in the beautiful city of Ceske Budějovice!

Title slide being projected on a screen for the BSP trypanosomiasis and leishmaniasis seminar

View of Ceske Budějovice from above. Beautiful city with coloured houses on a clear sunny day

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 13

bsky.app/profile/bung...

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Feb 1

The world is full of crazy and sad news, but here is a protein that localizes to only one of the two flagella

Fluorescence microscope image showing a protein that goes to only one flagellum

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 13

But I do not tweet about lab members' progress on trypanosome work because they may get annoyed

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 13

I guess I have been quite open about my ongoing diplonema project, showing PCR results, live cell imaging, IF attempts, some interesting localization. For example, my tweet about "one of two flagella" protein led to conversations with various people I had not talked to. It's been so much fun

Prachee Avasthi @pracheeac.bsky.social · Aug 13

If you're in academia or industry and have taken action to push the needle to make your research, science, data etc. more open and useful (even if you've been told it will damage your career or goals), I'd love to know about what you've done.
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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 13

I wish I'm talking about our place...

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 13

Core funding, Orbitrap Astral, Aquilos 2, super low facility charges, etc etc

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Reposted by Bungo Akiyoshi

Cees Dekker @ceesdekker.bsky.social · Aug 13

Building a synthetic cell together - nice common perspective written by many leading scientists who gathered in Shenzhen China for the inaugural ‘SynCell Global Summit’.

Check it out in Nature Comm: www.nature.com/articles/s41...

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 11

Hotel ISG, EMBL

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 10

In Tokyo last month. In Heidelberg this week. Let's see what kind of images we can get

Reposted by Bungo Akiyoshi

Gautam Dey @gautamdey.bsky.social · Aug 7

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 7

Thanks for your message. I sent the manuscript to Dick and he liked it. I did not have a chance to meet Jeremy Pickett-Heaps unfortunately

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 6

Thanks Rob! Proud to publish a first-author paper!

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 6

My attempt to become a professor was unsuccessful again but the diplonema tagging paper is now published in Open Biology. royalsocietypublishing.org/doi/10.1098/...

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Reposted by Bungo Akiyoshi

Lars Jansen Lab @jansenlab.bsky.social · Jul 29

The discovery of CENP-A, the centromere-specific histone H3 variant turns 40 years!
Grant Rowley wrote a wonderful historical piece on the cell cycle control of this fascinating piece of chromatin! Check it out.
link.springer.com/article/10.1...

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Reposted by Bungo Akiyoshi

Andrew Maclean @macleanlab.bsky.social · Jul 23

📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Postdoctoral Research Associate

We are looking for a talented and enthusiastic Postdoctoral researcher to join the Maclean lab to investigate the metabolism of the human parasite Toxoplasma gondii.

elxw.fa.em3.oraclecloud.com

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Reposted by Bungo Akiyoshi

Iain Cheeseman @iaincheeseman.bsky.social · Jul 23

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?

www.biorxiv.org/content/10.1...

Global inhibition of deadenylation stabilizes the transcriptome in mitotic cells

In the presence of cell division errors, mammalian cells can pause in mitosis for tens of hours with little to no transcription, while still requiring continued translation for viability. These unique...

www.biorxiv.org

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Reposted by Bungo Akiyoshi

bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · Jul 21

Subcellular proteomics of Paradiplonema papillatum reveals digestive capacity of the cell membrane and the plasticity of peroxisomes across euglenozoans https://www.biorxiv.org/content/10.1101/2025.07.16.665091v1

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Jul 2

They may well be, but additionally, I feel something is fundamentally different in diplonemids

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Jul 2

A lesson I learned from studying unconventional trypanosome kinetochores is that it's better not to make much assumptions, but I thought that the very basic assumptions as above should apply to any eukaryote. Non-traditional eukaryotes are so interesting

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Jul 2

We all make assumptions based on existing knowledge. My assumptions when studying mitosis are
- Cells divide sister chromatids
- Cohesin holds sisters together
- Kinetochores interact with spindle microtubules
I feel that at least one assumption is not valid in diplonemids. I am confused

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Bungo Akiyoshi @bungoakiyoshi.bsky.social · Jul 2

The problem is that the more I understand, the less it makes sense. Something is not right

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Apr 21

Working on under-studied organisms makes me feel stupid all the time. So many times I say "I don't know what I'm looking at"

Itai Yanai @itaiyanai.bsky.social · Apr 21

In today's episode of the Night Science Podcast we talk with Martin Schwartz from Yale about the importance of stupidity in science: while learning science makes you feel smart, true scientific discovery often involves feeling stupid, because it means venturing into the unknown.

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Reposted by Bungo Akiyoshi

Florian Wollweber @florianwollweber.bsky.social · Jun 27

After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6

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