Vusumuzi Ngonidzashe Hove
@vusumuzihove.bsky.social
Medicinal Chemistry Researcher👨🏾🔬🔬🇿🇼🇺🇸 | Pharmaceutical Scientist 💊 | PK/PD Modeling💻 | Biotech🧬 | Oncology💉 | O-Chem Tutor🧪 | @UBuffalo @UBmenstennis🎾🦬🤘🏿Alumnus🎓 | Zimbabwean Pro Tennis Player🎾🇿🇼 | Athlete 🚴🏿♂️🏃🏿♂️⌚️👟🇺🇸 | #BillsMafia 🏈🦬
https://linktr.ee/vusumuzihove
Reposted by Vusumuzi Ngonidzashe Hove
In a medical first, researchers report that they have implanted CRISPR-edited pancreas cells into a person with type 1 diabetes
go.nature.com/483h6qm
go.nature.com/483h6qm
Hope for diabetes: CRISPR-edited cells pump out insulin in a person – and evade immune detection
Edits create cells that don’t trigger an immune response, allowing implant recipient to forego immune-suppressing drugs.
go.nature.com
September 5, 2025 at 2:23 PM
In a medical first, researchers report that they have implanted CRISPR-edited pancreas cells into a person with type 1 diabetes
go.nature.com/483h6qm
go.nature.com/483h6qm
Reposted by Vusumuzi Ngonidzashe Hove
Posts about research on Bluesky receive substantially more attention than similar posts on X, formerly called Twitter
go.nature.com/45Ftiw4
go.nature.com/45Ftiw4
Research posts on Bluesky are more original — and get better engagement
Bluesky posts about science garner more likes and reposts than similar ones on X.
go.nature.com
August 29, 2025 at 8:28 AM
Posts about research on Bluesky receive substantially more attention than similar posts on X, formerly called Twitter
go.nature.com/45Ftiw4
go.nature.com/45Ftiw4
Reposted by Vusumuzi Ngonidzashe Hove
US FDA approves Boehringer Ingelheim's lung cancer treatment reut.rs/3J5lESN
US FDA approves Boehringer Ingelheim's lung cancer treatment
The U.S. Food and Drug Administration said on Friday it has approved Boehringer Ingelheim's drug for patients with a type of advanced lung cancer who have received prior treatment.
reut.rs
August 8, 2025 at 6:35 PM
US FDA approves Boehringer Ingelheim's lung cancer treatment reut.rs/3J5lESN
Reposted by Vusumuzi Ngonidzashe Hove
Novartis clears two Phase 3 studies in Sjögren’s disease, bringing a first-in-class drug one step closer to market.
endpoints.news/novartis-ant...
endpoints.news/novartis-ant...
Novartis plans Sjögren’s disease filings as antibody passes two Phase 3 studies
Novartis' ianalumab meets primary endpoint in two Phase 3 Sjögren's disease trials, positioning it as potential first targeted treatment for the autoimmune condition.
endpoints.news
August 11, 2025 at 1:59 PM
Novartis clears two Phase 3 studies in Sjögren’s disease, bringing a first-in-class drug one step closer to market.
endpoints.news/novartis-ant...
endpoints.news/novartis-ant...
Reposted by Vusumuzi Ngonidzashe Hove
An experimental weight-loss pill from Eli Lilly helped people lose up to about 12% of their body weight, a new study found, potentially clearing the way for the drug to be on the market next year,
Lilly Pill Helps People Lose Up to 12% of Body Weight, a Bit Less Than Expected
The experimental obesity medicine is one of two that could offer alternatives to weight-loss injections within the next year or so.
on.wsj.com
August 7, 2025 at 12:07 PM
An experimental weight-loss pill from Eli Lilly helped people lose up to about 12% of their body weight, a new study found, potentially clearing the way for the drug to be on the market next year,
Reposted by Vusumuzi Ngonidzashe Hove
Eli Lilly obesity pill disappoints in trial, sending shares down 12% on.ft.com/3HfLJOw
Eli Lilly obesity pill disappoints in trial, sending shares down 12%
Rival Novo Nordisk’s stock climbs 12%
on.ft.com
August 7, 2025 at 11:17 AM
Eli Lilly obesity pill disappoints in trial, sending shares down 12% on.ft.com/3HfLJOw
Reposted by Vusumuzi Ngonidzashe Hove
A study in mice finds that lithium depletion in the brain may be a trigger of Alzheimer’s and that replenishment could be a treatment.
www.statnews.com/2025/08/06/l...
www.statnews.com/2025/08/06/l...
Lithium, a treatment for bipolar disorders, might be a key to Alzheimer’s disease
A study in mice finds that lithium depletion in the brain may be a trigger of Alzheimer’s and that replenishment could be a treatment.
www.statnews.com
August 6, 2025 at 3:58 PM
A study in mice finds that lithium depletion in the brain may be a trigger of Alzheimer’s and that replenishment could be a treatment.
www.statnews.com/2025/08/06/l...
www.statnews.com/2025/08/06/l...
Reposted by Vusumuzi Ngonidzashe Hove
Pandemic preparedness in the US has been leveled a crippling blow with the cancellation of multiple #BARDA contracts to help develop mRNA vaccines. No other vaccine platform produces vaccine so quickly; without mRNA, Americans will have a long wait for pandemic vax. www.statnews.com/2025/08/05/m...
Health secretary RFK Jr. shuts door on U.S. investment in mRNA vaccine research
Vaccine experts and people steeped in pandemic preparedness expressed horror at the news that RFK Jr. has shut the door in U.S. investment in mRNA vaccine research.
www.statnews.com
August 5, 2025 at 10:59 PM
Pandemic preparedness in the US has been leveled a crippling blow with the cancellation of multiple #BARDA contracts to help develop mRNA vaccines. No other vaccine platform produces vaccine so quickly; without mRNA, Americans will have a long wait for pandemic vax. www.statnews.com/2025/08/05/m...
Reposted by Vusumuzi Ngonidzashe Hove
#Breaking: Health secretary RFK Jr. shuts door on U.S. investment in mRNA vaccine research
www.statnews.com/2025/08/05/m...
www.statnews.com/2025/08/05/m...
Health secretary RFK Jr. shuts door on U.S. investment in mRNA vaccine research
Vaccine experts and people steeped in pandemic preparedness expressed horror at the news that RFK Jr. has shut the door in U.S. investment in mRNA vaccine research.
www.statnews.com
August 5, 2025 at 11:07 PM
#Breaking: Health secretary RFK Jr. shuts door on U.S. investment in mRNA vaccine research
www.statnews.com/2025/08/05/m...
www.statnews.com/2025/08/05/m...
Reposted by Vusumuzi Ngonidzashe Hove
As the list of health benefits of semaglutide drugs grows, perhaps it is time to think about assessing their impact on people without medical conditions
We should consider testing Ozempic on healthy people
As the list of health benefits of semaglutide drugs grows, perhaps it is time to think about assessing their impact on people without medical conditions
www.newscientist.com
August 6, 2025 at 10:16 PM
As the list of health benefits of semaglutide drugs grows, perhaps it is time to think about assessing their impact on people without medical conditions
Reposted by Vusumuzi Ngonidzashe Hove
Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease
go.nature.com/3Jn8v7u
go.nature.com/3Jn8v7u
New hope for Alzheimer’s: lithium supplement reverses memory loss in mice
Studies in rodents and humans suggest that low levels of the metal contribute to cognitive decline.
go.nature.com
August 6, 2025 at 3:36 PM
Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease
go.nature.com/3Jn8v7u
go.nature.com/3Jn8v7u
Reposted by Vusumuzi Ngonidzashe Hove
The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.
With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency
Republicans on spending committee push back against proposed reorganization and overhead cuts
scim.ag
July 31, 2025 at 9:37 PM
The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.
Reposted by Vusumuzi Ngonidzashe Hove
Multiple federal agencies are suspending research funding at UCLA over allegations it didn’t properly deal with antisemitism on campus. scim.ag/4lbLAcx
NSF and NIH suspend grants to UCLA
Move follows Trump administration finding that school didn’t effectively combat antisemitism
scim.ag
August 1, 2025 at 6:13 PM
Multiple federal agencies are suspending research funding at UCLA over allegations it didn’t properly deal with antisemitism on campus. scim.ag/4lbLAcx
Reposted by Vusumuzi Ngonidzashe Hove
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV
go.nature.com/4ov7WZI
go.nature.com/4ov7WZI
mRNA vaccines for HIV trigger strong immune response in people
Results from early-stage trial show that 80% of participants who received one of two HIV vaccine candidates produced antibodies against viral proteins.
go.nature.com
August 1, 2025 at 8:40 AM
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV
go.nature.com/4ov7WZI
go.nature.com/4ov7WZI
Reposted by Vusumuzi Ngonidzashe Hove
A new study found that the immune system’s response to viral infections in the lungs might be contributing to cancer cell activation.
www.statnews.com/2025/07/30/f...
www.statnews.com/2025/07/30/f...
Viral infections in the lung, like Covid-19, can reactivate dormant cancer cells
Certain respiratory infections could trigger a reawakening of dormant cancer cells in the body, according to a new study.
www.statnews.com
July 30, 2025 at 3:18 PM
A new study found that the immune system’s response to viral infections in the lungs might be contributing to cancer cell activation.
www.statnews.com/2025/07/30/f...
www.statnews.com/2025/07/30/f...
Reposted by Vusumuzi Ngonidzashe Hove
Scientists used a mRNA-based vaccine to reliably trigger antibodies that block HIV infection in people and monkeys
www.statnews.com/2025/07/30/m...
www.statnews.com/2025/07/30/m...
Using mRNA, scientists overcome a key challenge to HIV vaccines
Scientists used a mRNA-based vaccine to reliably trigger antibodies that block HIV infection in people and monkeys
www.statnews.com
July 30, 2025 at 7:36 PM
Scientists used a mRNA-based vaccine to reliably trigger antibodies that block HIV infection in people and monkeys
www.statnews.com/2025/07/30/m...
www.statnews.com/2025/07/30/m...
Reposted by Vusumuzi Ngonidzashe Hove
Eli Lilly’s blockbuster diabetes drug Mounjaro matched the ability of an older treatment to prevent major heart complications in a large trial.
www.statnews.com/2025/07/31/e...
www.statnews.com/2025/07/31/e...
Lilly’s diabetes drug Mounjaro matches heart benefit of older treatment
Eli Lilly’s blockbuster diabetes drug Mounjaro matched the ability of an older treatment to prevent major heart complications in a large trial.
www.statnews.com
July 31, 2025 at 1:36 PM
Eli Lilly’s blockbuster diabetes drug Mounjaro matched the ability of an older treatment to prevent major heart complications in a large trial.
www.statnews.com/2025/07/31/e...
www.statnews.com/2025/07/31/e...
Reposted by Vusumuzi Ngonidzashe Hove
A generative artificial-intelligence tool has designed a synthetic CRISPR system that successfully edits human DNA
go.nature.com/4mFJBPd
go.nature.com/4mFJBPd
AI expands the repertoire of CRISPR-associated proteins for genome editing
A generative artificial-intelligence tool has designed a synthetic CRISPR system that successfully edits human DNA and sharply reduces off-target effects.
go.nature.com
July 31, 2025 at 11:34 AM
A generative artificial-intelligence tool has designed a synthetic CRISPR system that successfully edits human DNA
go.nature.com/4mFJBPd
go.nature.com/4mFJBPd
Reposted by Vusumuzi Ngonidzashe Hove
Scientists have created a tool that manufactures working proteins directly on the surfaces of cells
go.nature.com/3IMPyv0
go.nature.com/3IMPyv0
SMART tool builds proteins on cell surfaces
Researchers can target effector proteins to cells on the basis of which molecules those cells express.
go.nature.com
July 31, 2025 at 12:20 PM
Scientists have created a tool that manufactures working proteins directly on the surfaces of cells
go.nature.com/3IMPyv0
go.nature.com/3IMPyv0
Reposted by Vusumuzi Ngonidzashe Hove
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse
go.nature.com/41iIdJR
go.nature.com/41iIdJR
‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu
Inflammation from the respiratory infections seems to be the culprit, study in mice finds.
go.nature.com
July 30, 2025 at 3:19 PM
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse
go.nature.com/41iIdJR
go.nature.com/41iIdJR
Reposted by Vusumuzi Ngonidzashe Hove
The brain activates front-line immune cells in response to the mere sight of a sick person
go.nature.com/475cIXn
go.nature.com/475cIXn
The brain fires up immune cells when sick people are nearby
When people viewed virtual avatars with coughs or rashes, their brains triggered an immune response.
go.nature.com
July 29, 2025 at 12:07 PM
The brain activates front-line immune cells in response to the mere sight of a sick person
go.nature.com/475cIXn
go.nature.com/475cIXn
Reposted by Vusumuzi Ngonidzashe Hove
NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.
www.statnews.com/2025/07/29/n...
www.statnews.com/2025/07/29/n...
NIH is shrinking the number of research projects it funds due to a new Trump policy
NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.
www.statnews.com
July 29, 2025 at 1:34 PM
NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.
www.statnews.com/2025/07/29/n...
www.statnews.com/2025/07/29/n...
Reposted by Vusumuzi Ngonidzashe Hove
Researchers’ chances of winning a grant from the National Institutes of Health have dropped under a new policy. scim.ag/4f7uew2
Odds of winning NIH grants plummet as new funding policy and spending delays bite
Funding multiyear grants up front will sharply cut number of investigators receiving awards
scim.ag
July 28, 2025 at 10:10 PM
Researchers’ chances of winning a grant from the National Institutes of Health have dropped under a new policy. scim.ag/4f7uew2
Reposted by Vusumuzi Ngonidzashe Hove
Decreased funding, reduced opportunities and growing uncertainty has made life tough for international postdocs living in the US
go.nature.com/4mg4ct9
go.nature.com/4mg4ct9
Meet the early career scientists planning to leave the United States
Decreased funding, reduced opportunities and growing uncertainty has made life tough for international postdocs living in the US.
go.nature.com
July 25, 2025 at 12:35 PM
Decreased funding, reduced opportunities and growing uncertainty has made life tough for international postdocs living in the US
go.nature.com/4mg4ct9
go.nature.com/4mg4ct9
Reposted by Vusumuzi Ngonidzashe Hove
Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria
go.nature.com/4nUQHAq
go.nature.com/4nUQHAq
‘Landmark’ study: three-person IVF leads to eight healthy children
Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria.
go.nature.com
July 17, 2025 at 9:28 AM
Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria
go.nature.com/4nUQHAq
go.nature.com/4nUQHAq