Assessing chromatin accessibility in rare cell populations within tissue remains a key challenge. To address this, we present a low-input ATAC workflow optimized for liver ILCs. The protocol is valid...

Rudensky and colleagues demonstrate a context-dependent differential requirement for Foxp3 for Treg cell transcriptional and functional programs.

WASHINGTON — The National Academy of Medicine (NAM) today announced that Carl F. Nathan is the recipient of the 2025 David and Beatrix Hamburg Award for

This Review discusses what comprises the ‘cancer microbiome’, summarizing the studies on tumour-associated microbes, examining the evidence and assessing their impact on the disease.

The 2025 Innovator Awards grantee projects explore new ways to reduce inflammation and restore gut health, targeted treatment options with fewer side effects and the chance for lasting healing, and th...

Regulatory T cells curb noxious sensory signaling to dampen cutaneous inflammation, a neuromodulatory mechanism for immunosuppression.

Artis and colleagues show that enteric neurons produce CGRP-related ADM2 to promote intestinal tissue-protective functions in ILC2s.

Sun and colleagues report that the transcription factor TCF19 regulates calcium signaling and cell cycling progression in NK cells and is required for innate and adaptive NK cell responses to viral in...

The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defender...

Anandasabapathy and colleagues show that the inhibitory receptor PD-1 impacts the specification of tissue-resident memory T cells in the skin.

M. tuberculosis must survive within multiple macrophage populations during infection, including alveolar macrophages (AM) and recruited inflammatory macrophages. In mice, itaconate, produced in macrop...

The International Cytokine & Interferon Society proudly announces these 2025 Young Investigator Award winners. The Sidney & Joan Pestka Graduate and Post-Graduate Awards, sponsored by PBL Assay Services Post-graduate awardee, Alexander Lercher, PhD, The Rockefeller University is currently an HFSP long-term fellow and Harvey L. Karp postdoctoral fellow in the laboratory of Charles M. Rice

Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the patho...