Wonuola Akingbuwa
@wonuola.bsky.social
110 followers 180 following 5 posts
Assistant professor at VU Amsterdam Psychiatric genetics
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wonuola.bsky.social
Have you ever wondered about nonlinearity in bivariate genetic associations? Or wondered whether global estimators like genetic correlations tell the full story about the relationship between two phenotypes, then check out @michelnivard.bsky.social thread on some work we’ve been doing to model this.
michelnivard.bsky.social
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
Reposted by Wonuola Akingbuwa
tedmond.bsky.social
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
wonuola.bsky.social
Thanks @michelnivard.bsky.social for being an awesome collaborator and shoutout whoever had the question or comment at #WCPG22 that inspired our eventual approach to this.
wonuola.bsky.social
This one’s been in the works for a minute and I’m happy to finally be able to share what we’ve come up with, and looking forward to discussions and feedback you may have.
wonuola.bsky.social
Have you ever wondered about nonlinearity in bivariate genetic associations? Or wondered whether global estimators like genetic correlations tell the full story about the relationship between two phenotypes, then check out @michelnivard.bsky.social thread on some work we’ve been doing to model this.
michelnivard.bsky.social
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
Reposted by Wonuola Akingbuwa
michelnivard.bsky.social
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
Reposted by Wonuola Akingbuwa
helenadavies.bsky.social
Outreach in psychiatric genetics - What is it? Why do we need it? How can we do it well?

Join me, Niamh Ryan, and Cindy Bulik this Friday (6th) at 10am EST / 4pm CET / 3pm UTC where we'll discuss all of this for the PGC (@pgcgenetics.bsky.social) World Wide Lab 🌎

🔗 us02web.zoom.us/j/88690327502
wonuola.bsky.social
ooohh thanks! super relevant to our discussion earlier today