Our review on disease resistance gene diversity in Triticeae is finally online 🌾🌾! Gained so many insights writing it with Yinghui Li & Liubov Govta and from the guidance of gittacoaker.bsky.social & Tzion Fahima. Fascinated by plant resistance gene diversity—excited to share!

Registrations are rolling in for the 2025 Stromlo Plant Pathology meeting in Canberra (Nov 27–28)! Secure your spot! Speakers: @yasukadota.bsky.social, Cecille Segonzac, @thamlab.bsky.social, @yichangsung.bsky.social, Tek Tay & @danielsyu.bsky.social. Register at tinyurl.com/3e3tx9j2
#strompath25

Submitted my first NIH grant proposal ! 🤞🤞🤞

Excited this MS is out! Here, we genome edited Pire in tomato, a conserved E3 ligase controlling NADPH oxidase accumulation in Arabidopsis. Edited lines exhibited enhanced resistance to foliar bacterial pathogens, but not two root colonizing pathogens. #PlantImmunity
academic.oup.com/plcell/artic...

👀 EFR-mediated PTI restricts transient transformation and genome editing, but not T-DNA integration.
This study combines floral stage targeting 🌷, immune evasion 🛡️, and Agrobacterium engineering 🔧 to boost plant genome editing efficiency.
#Agrobacterium
#GenomeEditing
www.biorxiv.org/content/10.1...

Paper submitted! One of the last in @jerrytli.bsky.social’s stellar PhD.

Phoebe Sinner and @yichangsung.bsky.social presented their work on vector borne effectors and Tandem Kinase Proteins @ucdavis.bsky.social host microbe interactions meeting. Great job by both!!

Our Research Briefing on the tandem kinase proteins paper is online now!
Curious about the story behind our TKP paper?
📄 Research Briefing: www.nature.com/articles/s41...
📄 Research article: www.nature.com/articles/s41...

Thank you Shahid

Story behind our recent paper on tandem kinases is out! Written by @yichangsung.bsky.social. #MPMI #PlantBiology www.nature.com/articles/s41...

Can’t wait to see more TKP–effector pairs conferring resistance to different diseases

Our in planta and in vitro results show that RWT4 directly and specifically binds to AvrPWT4. This interaction requires RWT4’s N-terminal kinase duplication domain, which functions like an integrated domain (ID) seen in some NLR proteins. The binding is essential for RWT4 recognition.

We also showed that RWT4 is an active kinase, and its kinase activity is essential for triggering defense responses.

Wheat TKP RWT4 directly binds to the fungal effector AvrPWT4 to trigger immune responses against the devastating Magnaporthe oryzae. We developed a rice protoplast system to reconstitute RWT4–AvrPWT4 recognition in a monocot background—providing a useful model for future TKP studies.

🌾 Excited to share our research on plant tandem kinase proteins (TKPs)! It’s been fascinating to explore how TKPs interplay effectors to activate plant immunity. Big thanks to my supervisor @gittacoaker.bsky.social, my undergrad student Suji Baik, and our collaborators—it's truly a team effort!

Can’t wait to see more TKP–effector pairs conferring resistance to different diseases!

I'm very excited our most recent work on plant tandem kinases (TKPs) has finally been published! TKPs are a fascinating protein family conferring disease resistance to fungi. Originally in bioRxiv. Many thanks to @yichangsung.bsky.social for leading this work. 🧵
www.nature.com/articles/s41...

First post on Bluesky is to Stand up for Science!