Yojet
@yojet.bsky.social
Final year PhD candidate working to uncover the role of lipid 5-phosphatase in human brain development @NCBS, India.
Interested in neuroimmune interactions, physiology, and microglia.
Interested in neuroimmune interactions, physiology, and microglia.
One of the most rewarding aspects of this work is watching neurons and astrocytes come alive through calcium imaging!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
November 11, 2025 at 6:53 PM
One of the most rewarding aspects of this work is watching neurons and astrocytes come alive through calcium imaging!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
Very excited to share that my PhD work is out!
Neurons carry ~5,000–10,000 molecules of PI(4,5)P₂ per μm² of membrane. What happens to human brain development when that number changes? I address this using a disease-in-a-dish model of Lowe Syndrome:
www.embopress.org/doi/10.1038/...
Neurons carry ~5,000–10,000 molecules of PI(4,5)P₂ per μm² of membrane. What happens to human brain development when that number changes? I address this using a disease-in-a-dish model of Lowe Syndrome:
www.embopress.org/doi/10.1038/...
November 11, 2025 at 6:53 PM
Very excited to share that my PhD work is out!
Neurons carry ~5,000–10,000 molecules of PI(4,5)P₂ per μm² of membrane. What happens to human brain development when that number changes? I address this using a disease-in-a-dish model of Lowe Syndrome:
www.embopress.org/doi/10.1038/...
Neurons carry ~5,000–10,000 molecules of PI(4,5)P₂ per μm² of membrane. What happens to human brain development when that number changes? I address this using a disease-in-a-dish model of Lowe Syndrome:
www.embopress.org/doi/10.1038/...
Ever wondered, what happens if phospholipid PIP2 levels are disturbed in neurons? Turns out that, PIP2 and Notch are linked! I highlight these findings in my PhD manuscript, finally out on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 10, 2024 at 7:37 PM
Ever wondered, what happens if phospholipid PIP2 levels are disturbed in neurons? Turns out that, PIP2 and Notch are linked! I highlight these findings in my PhD manuscript, finally out on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...