Yudong Gao
@yudonggao.bsky.social
Neuroscientist, corgi parent. Views are my own.
The existence of specialized phosphatases in regulating the AIS was unclear. In this initial report, we show that a PP2A subunit is enriched at the AIS and contributes to its local phosphoregulation. Fun collaboration with Dr. Matthew Rasband's lab, and thanks to all authors for their contribution!
A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment - Nature Communications
The existence of phosphatases specialized in regulating the axon initial segment (AIS) was unclear. Here, the authors show that a PP2A-B55 subunit is selectively enriched at the AIS and contributes to...
www.nature.com
December 3, 2025 at 4:43 PM
The existence of specialized phosphatases in regulating the AIS was unclear. In this initial report, we show that a PP2A subunit is enriched at the AIS and contributes to its local phosphoregulation. Fun collaboration with Dr. Matthew Rasband's lab, and thanks to all authors for their contribution!
Reposted by Yudong Gao
Phosphorylation at the AIS is back! Nice work from @yudonggao.bsky.social and Matt Rasband on the presence and role of the PP2A phosphatase subunit Ppp2r2c using HiUGE tagging www.nature.com/articles/s41...
December 3, 2025 at 12:07 PM
Phosphorylation at the AIS is back! Nice work from @yudonggao.bsky.social and Matt Rasband on the presence and role of the PP2A phosphatase subunit Ppp2r2c using HiUGE tagging www.nature.com/articles/s41...