"The roles of human endogenous retrovirus in neurodegenerative diseases: A systematic review"
#HERVs
#HERV-K
#HERV-W
www.sciencedirect.com/science/arti...
#HERVs
#HERV-K
#HERV-W
www.sciencedirect.com/science/arti...
The roles of human endogenous retrovirus in neurodegenerative diseases: A systematic review
Human endogenous retroviruses (HERVs) constitute ∼8 % of the human genome, far exceeding the 2 % occupied by protein-coding genes. Although most HERV …
www.sciencedirect.com
December 7, 2025 at 12:44 PM
"The roles of human endogenous retrovirus in neurodegenerative diseases: A systematic review"
#HERVs
#HERV-K
#HERV-W
www.sciencedirect.com/science/arti...
#HERVs
#HERV-K
#HERV-W
www.sciencedirect.com/science/arti...
Was the Wuhan 'COVID Spike' Really HERV-K—A Human Protein Mistaken for a Virus?
open.substack.com/pub/jonfleet...
open.substack.com/pub/jonfleet...
Was the Wuhan 'COVID Spike' Really HERV-K—A Human Protein Mistaken for a Virus?
Does a new analysis suggest the Wuhan “virus” may have been a human stress protein mistaken for a pathogen?
open.substack.com
November 6, 2025 at 10:56 PM
Was the Wuhan 'COVID Spike' Really HERV-K—A Human Protein Mistaken for a Virus?
open.substack.com/pub/jonfleet...
open.substack.com/pub/jonfleet...
#HervéTélémache #Haitian
Hervé Télémache (1937 - 2022)
L'ÉTOILE ROUGE (VUE CAVALIERE N°1), 1991
Acrylic on canvas mounted on panel
Hervé Télémache (1937 - 2022)
L'ÉTOILE ROUGE (VUE CAVALIERE N°1), 1991
Acrylic on canvas mounted on panel
November 2, 2025 at 5:42 AM
#HervéTélémache #Haitian
Hervé Télémache (1937 - 2022)
L'ÉTOILE ROUGE (VUE CAVALIERE N°1), 1991
Acrylic on canvas mounted on panel
Hervé Télémache (1937 - 2022)
L'ÉTOILE ROUGE (VUE CAVALIERE N°1), 1991
Acrylic on canvas mounted on panel
November 1, 2025 at 5:59 AM
October 31, 2025 at 4:49 AM
#HervéTélémache #Haitian
Hervé Télémache (1937 - 2022)
ACCROCHE-SOLEIL, 1973
Collage and pencil on paper
Hervé Télémache (1937 - 2022)
ACCROCHE-SOLEIL, 1973
Collage and pencil on paper
October 30, 2025 at 4:58 AM
#HervéTélémache #Haitian
Hervé Télémache (1937 - 2022)
ACCROCHE-SOLEIL, 1973
Collage and pencil on paper
Hervé Télémache (1937 - 2022)
ACCROCHE-SOLEIL, 1973
Collage and pencil on paper
October 29, 2025 at 5:20 AM
Crystal structure of HERV-K envelope glycoprotein surface subunit https://www.biorxiv.org/content/10.1101/2025.10.24.684402v1
October 25, 2025 at 2:46 AM
Crystal structure of HERV-K envelope glycoprotein surface subunit https://www.biorxiv.org/content/10.1101/2025.10.24.684402v1
Crystal structure of HERV-K envelope glycoprotein surface subunit https://www.biorxiv.org/content/10.1101/2025.10.24.684402v1
October 25, 2025 at 2:46 AM
Crystal structure of HERV-K envelope glycoprotein surface subunit https://www.biorxiv.org/content/10.1101/2025.10.24.684402v1
"P17-27 A key biodistribution and immunotoxicity study of a new therapeutic antibody for Amyotrophic Lateral Sceloris treatment"
#ALS #HERV-K
#EUROTOX2025
👇
www.sciencedirect.com/science/arti...
#ALS #HERV-K
#EUROTOX2025
👇
www.sciencedirect.com/science/arti...
P17-27 A key biodistribution and immunotoxicity study of a new therapeutic antibody for Amyotrophic Lateral Sceloris treatment
An animal study was performed at ERBC Dommartin to evaluate the biodistribution of GNK301, an IgG4 humanized antibody neutralizing the HERV-K ENV (K-E…
www.sciencedirect.com
September 14, 2025 at 6:23 PM
"P17-27 A key biodistribution and immunotoxicity study of a new therapeutic antibody for Amyotrophic Lateral Sceloris treatment"
#ALS #HERV-K
#EUROTOX2025
👇
www.sciencedirect.com/science/arti...
#ALS #HERV-K
#EUROTOX2025
👇
www.sciencedirect.com/science/arti...
🧬 Our DNA's ancient viruses: savior or destroyer? Scientists at La Jolla just unveiled HERV-K Env protein structure! This "dark matter" found on cancer & autoimmune cells is a potential "golden target" for therapies.
🛡️ What a breakthrough! But honestly, I can't help but wonder if we're opening a P
🛡️ What a breakthrough! But honestly, I can't help but wonder if we're opening a P
沉睡在DNA中的远古病毒被唤醒，是敌还是友？ - cnBeta.COM 移动版
人类基因组中有8%实际上来自远古病毒，这部分病毒残留被称为人类内源性逆转录病毒（HERVs），通常处于沉默状态，被视为无用的“基因暗物质”。但最新研究表明，它们可能成为未来医学的关键之一。
m.cnbeta.com.tw
September 4, 2025 at 4:12 AM
🧬 Our DNA's ancient viruses: savior or destroyer? Scientists at La Jolla just unveiled HERV-K Env protein structure! This "dark matter" found on cancer & autoimmune cells is a potential "golden target" for therapies.
🛡️ What a breakthrough! But honestly, I can't help but wonder if we're opening a P
🛡️ What a breakthrough! But honestly, I can't help but wonder if we're opening a P
A large proportion of what is de-repressed are IAP (Intracisternal Alpha Particle) elements, mouse specific ERVK family members, which are the closest functional analogs to human HERV-K.
With a consensus RNA probe, we can visualise locations of IAP transcripts in situ.
With a consensus RNA probe, we can visualise locations of IAP transcripts in situ.
September 1, 2025 at 12:42 PM
A large proportion of what is de-repressed are IAP (Intracisternal Alpha Particle) elements, mouse specific ERVK family members, which are the closest functional analogs to human HERV-K.
With a consensus RNA probe, we can visualise locations of IAP transcripts in situ.
With a consensus RNA probe, we can visualise locations of IAP transcripts in situ.
Check out the official press release highlighting our latest paper on the structure of the human endogenous retrovirus K (HERV-K) envelope protein! www.lji.org/news-events/...
A stunning first look at the viruses inside us
LJI scientists uncover a new avenue for stopping cancers, autoimmune diseases, and more.
www.lji.org
August 28, 2025 at 11:29 PM
Check out the official press release highlighting our latest paper on the structure of the human endogenous retrovirus K (HERV-K) envelope protein! www.lji.org/news-events/...
Excited to share our Science Advances paper reporting the first 3D structure of HERV‑K Env—a novel therapeutic target in cancer and autoimmune diseases. www.science.org/doi/10.1126/...
Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM
Structural snapshots and antibodies illuminate a viral protein within the dark matter of the genome that may be active in disease.
www.science.org
August 28, 2025 at 11:28 PM
Excited to share our Science Advances paper reporting the first 3D structure of HERV‑K Env—a novel therapeutic target in cancer and autoimmune diseases. www.science.org/doi/10.1126/...
Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM pubmed.ncbi.nlm.nih.gov/40864726/ #cryoem
August 28, 2025 at 8:36 PM
Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM pubmed.ncbi.nlm.nih.gov/40864726/ #cryoem
Validation experiments confirmed the elevated expression of these HERVs, suggesting a potential association with the disease. Phylogenetic analysis indicates these HERVs may represent new species within the HERV-K family.
August 6, 2025 at 8:46 PM
Validation experiments confirmed the elevated expression of these HERVs, suggesting a potential association with the disease. Phylogenetic analysis indicates these HERVs may represent new species within the HERV-K family.
This study analyzed blood transcriptome data from children with Kawasaki disease and healthy controls, identifying two novel HERV gene sequences (HERV-K-2177 and HERV-K-3157) that were significantly upregulated in patients.
August 6, 2025 at 8:46 PM
This study analyzed blood transcriptome data from children with Kawasaki disease and healthy controls, identifying two novel HERV gene sequences (HERV-K-2177 and HERV-K-3157) that were significantly upregulated in patients.
Conclusion: Our results denote an altered and chronically aroused anti-viral profile against latent viruses in ME/CFS. SARS-CoV-2 infection even in its mild/asymptomatic form is a potent trigger for reactivation of latent herpesviruses (EBV, HHV6) and endogenous retroviruses (HERV-K), as detected by
August 5, 2025 at 2:33 AM
Conclusion: Our results denote an altered and chronically aroused anti-viral profile against latent viruses in ME/CFS. SARS-CoV-2 infection even in its mild/asymptomatic form is a potent trigger for reactivation of latent herpesviruses (EBV, HHV6) and endogenous retroviruses (HERV-K), as detected by
Conclusion: Our results denote an altered and chronically aroused anti-viral profile against latent viruses in ME/CFS. SARS-CoV-2 infection even in its mild/asymptomatic form is a potent trigger for reactivation of latent herpesviruses (EBV, HHV6) and endogenous retroviruses (HERV-K),
August 5, 2025 at 2:33 AM
Conclusion: Our results denote an altered and chronically aroused anti-viral profile against latent viruses in ME/CFS. SARS-CoV-2 infection even in its mild/asymptomatic form is a potent trigger for reactivation of latent herpesviruses (EBV, HHV6) and endogenous retroviruses (HERV-K),
Results: At 3-6 months after mild/asymptomatic SARS-CoV-2 infection, virus-specific antibodies in saliva were substantially induced signifying a strong reactivation of latent viruses (EBV, HHV6 and HERV-K) in both cohorts. In patients with ME/CFS, antibody responses were significantly stronger, in
August 5, 2025 at 2:29 AM
Results: At 3-6 months after mild/asymptomatic SARS-CoV-2 infection, virus-specific antibodies in saliva were substantially induced signifying a strong reactivation of latent viruses (EBV, HHV6 and HERV-K) in both cohorts. In patients with ME/CFS, antibody responses were significantly stronger, in
Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome pubmed.ncbi.nlm.nih.gov/36341457/ (2022)
#ME/CFS #pwME #ViralReactivation #COVID-19 #EBV #EBNA1 #HHV6 #HERV-K
#ME/CFS #pwME #ViralReactivation #COVID-19 #EBV #EBNA1 #HHV6 #HERV-K
Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome - PubMed
Our results denote an altered and chronically aroused anti-viral profile against latent viruses in ME/CFS. SARS-CoV-2 infection even in its mild/asymptomatic form is a potent trigger for reactivation ...
pubmed.ncbi.nlm.nih.gov
August 5, 2025 at 2:29 AM
Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome pubmed.ncbi.nlm.nih.gov/36341457/ (2022)
#ME/CFS #pwME #ViralReactivation #COVID-19 #EBV #EBNA1 #HHV6 #HERV-K
#ME/CFS #pwME #ViralReactivation #COVID-19 #EBV #EBNA1 #HHV6 #HERV-K
A study led by Prof. Oltra, who has previously worked on ME Research UK-funded projects, has identified that certain markers in the blood could differentiate ‘post-COVID-19 condition’ from those with 'ME/CFS', and those with fibromyalgia.
Read more: bit.ly/4o6g4zv
#MEcfs #CFS #LongCovid #Fibro
Read more: bit.ly/4o6g4zv
#MEcfs #CFS #LongCovid #Fibro
July 28, 2025 at 3:10 PM
A study led by Prof. Oltra, who has previously worked on ME Research UK-funded projects, has identified that certain markers in the blood could differentiate ‘post-COVID-19 condition’ from those with 'ME/CFS', and those with fibromyalgia.
Read more: bit.ly/4o6g4zv
#MEcfs #CFS #LongCovid #Fibro
Read more: bit.ly/4o6g4zv
#MEcfs #CFS #LongCovid #Fibro
The prefusion structure of the HERV-K (HML-2) Env spike complex pubmed.ncbi.nlm.nih.gov/40632556/ #cryoem
July 10, 2025 at 2:04 PM
The prefusion structure of the HERV-K (HML-2) Env spike complex pubmed.ncbi.nlm.nih.gov/40632556/ #cryoem
Identification and Characterization of Functional and Trans-dominant Negative HERV-K (HML-2) Rec Proteins Encoded in the Human Genome. https://www.biorxiv.org/content/10.1101/2025.07.07.663474v1
July 7, 2025 at 9:30 PM
Identification and Characterization of Functional and Trans-dominant Negative HERV-K (HML-2) Rec Proteins Encoded in the Human Genome. https://www.biorxiv.org/content/10.1101/2025.07.07.663474v1