Check out the official press release highlighting our latest paper on the structure of the human endogenous retrovirus K (HERV-K) envelope protein! www.lji.org/news-events/...

Excited to share our Science Advances paper reporting the first 3D structure of HERV‑K Env—a novel therapeutic target in cancer and autoimmune diseases. www.science.org/doi/10.1126/...

Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @cellcellpress.bsky.social www.cell.com/cell/fulltex.... What’s new?

Just launched a web app for the cryo-EM community!
Upload your half maps → get FSC curves with confidence intervals using bootstrap or Fisher z-transform.
Try it here: fscerrorbar-bpamnw2rerqekapp5veeddq.streamlit.app
#CryoEM #OpenScience #FSC

Thrilled to share these experiments on shaping focused ion beams to explore different ways of milling. Here, we explore using different beam geometries to generate cellular thin sections/lamellae. The video shows elongating the beam on a charging spot burn www.biorxiv.org/content/10.1...

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social

🔗 Preprint here tinyurl.com/3a74uanv

Almost all grant-review meetings remain suspended at the US National Institutes of Health, preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.

https://go.nature.com/418B5Pm

These NIH funding cuts threaten research happening in Delaware on heart disease, cancer, diabetes, stroke recovery, & more.

This is what this administration is focused on. Not lowering your household costs.

Please consider using this link to ask Congress to protect NIH & medical research. It only takes a minute to complete.

Thank you so much!

#NIH #cancer #congress #medsky #cansky #academicresearch #research #science #politics #uspol
#EduSky #PhDSky #AcademicSky #bluecrew #bluesky #megaboost

Excited to share my friend Manfred Auer’s new book “Introduction to biological imaging”! Dive into the fascinating world of biological imaging and explore cutting-edge techniques. Check it out here www.wiley.com/en-us/Introd... #biologicalimaging #imaging #volumeEM #TEM #structure

🙌📽️🗣️The vEM Technology Forum is now on YouTube!

We have made available online now the sessions and challenge panels held at the vEM Technology Forum last year!

📽️Youtube playlist👉 bit.ly/433ByVM

Thanks to our sponsors and to all participants who made our vEM Technology Forum possible! ✨🤩

In a study involving >500 people, the AI identified a range of infections and health conditions, as well as whether participants had received a flu vaccine.

https://go.nature.com/4gPUpGT

Introducing cryoTIGER - a computational alternative to denser sampling during tilt series acquisition in cryo-ET. Congratulations to SCALE @scale-cluster-ffm.bsky.social members Beata Turonova @mpibp.bsky.social, Martin Beck @becklab.bsky.social & Gerhard Hummer @hummerlab.bsky.social

In @justinditrani.bsky.social final postdoc paper (with contributions from many others) we show that forming/purifying vesicles (here from M. smegmatis) allows structure det'n of *endogenous* membrane proteins in their *native lipid bilayer*
🧵 on methods & TB biology...
www.pnas.org/doi/full/10....

If you are interested in postdoctoral research on ligand-gated ion channels and the synapse, or simulation/AI methods for structural biology - drop me a line if you'll be around at Biophysical Society in LA! #bps2025 #bps #biophysics

Attending #BPS2025? Want to know more about tangible steps you can take to challenge the attacks on science in the U.S.? Please attend an Emergency Town Hall Meeting on Tuesday at 1:30! @biophysicalsoc.bsky.social @blackinbiophys.bsky.social Please spread the word!

Excited to give a talk on human endogenous retroviruses at the Cryo-EM Subgroup Symposium today at #BPS2025! Please come check out my poster B99 on Sunday afternoon—looking forward for great discussions!

#Biophysics #CryoEM #Retroviruses #StructuralBiology#HERV

#medsky#pedsky#idsky#immunosky 🧪
In the midst of all of the scary headlines recently, I thought I could take a moment to share a bit of good news: for the first time in history, a malaria vaccine with >90% efficacy seems to be within reach!

Here’s why that’s a really big deal for EVERYONE 🧵

Been thinking about creating a collection of good protein structure figures, as inspiration for my own work.

#1 www.nature.com/articles/s41...

🤔❓💻🧫🦠
Do you know that the ImageJ plugin DenoisEM can improve the quality of large-scale volumes of EM imaging?

The authors used this plugin to analyse EM volumes obtained either by FIB-SEM and SBF-SEM using automated analysis.

Paper courtesy of Joris Roels et al.

bioimagingcore.be/DenoisEM

The ear and the nose are squishy and stretchy thanks in part to ‘bubble wrap’ cells that provide extra cushioning and structural support to various body parts, a wide-ranging study shows.

www.nature.com/articles/d41...