#Medicinalchemistry
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rscjapan.bsky.social
Just Published✨ | Chemical Science
RIKEN高橋俊二先生、東北大学土井隆行先生らによる
Characterization of the ketoreductase domain of pikromycin module 2
pubs.rsc.org/en/content/a...
#naturalProduct #medicinalChemistry
December 29, 2025 at 2:11 AM
purescience.news
How Discarded Water Bottles Are Being Turned Into Cancer Drugs #Science #Chemistry #MedicinalChemistry #CancerResearch #Sustainability
How Discarded Water Bottles Are Being Turned Into Cancer Drugs
All the science news you can handle in a single feed
purescience.news
December 20, 2025 at 8:27 PM
purescience.news
After 50 Years, MIT Chemists Finally Synthesize Elusive Anti-Cancer Compound #Science #Chemistry #MedicinalChemistry #CancerResearch #ChemistryInnovation #MIT
After 50 Years, MIT Chemists Finally Synthesize Elusive Anti-Cancer Compound
Preliminary studies indicate that derivatives of verticillin A can kill certain types of glioma cells. MIT chemists have, for the first time, successfully created in the laboratory a fungal molecule called...
purescience.news
December 10, 2025 at 9:45 AM
synopenjournal.bsky.social
📢 Cheminar Alert!
Our next Thieme #Cheminar is coming up: “Small Molecules in #MedicinalChemistry”
📅 Dec 10, 5:00 PM (CET)

Featuring Prof. Arlene Corrêa and Prof. Kelvin Billingsley, with Prof. Debabrata Maiti (EiC of @synlettjournal.bsky.social) chairing.

🔗 Register now: bit.ly/4aDJWie
#ChemSky
December 5, 2025 at 9:15 AM
mol-biomed.bsky.social
#Highlight
Disrupting the SHOC2-RAS Nexus: a new frontier in targeting RAS-Driven cancers doi.org/10.1186/s435...

The highlighted article in @nature.com : doi.org/10.1038/s415...

#Cancer #MedicinalChemistry #XrayCrystallography
Disrupting the SHOC2-RAS Nexus: a new frontier in targeting RAS-Driven cancers - Molecular Biomedicine
Molecular Biomedicine -
doi.org
December 5, 2025 at 3:22 AM
chemistry-tuw.bsky.social
🔬The 2025 Dieter Binder Lectureship brought this years awardee Dr. Peter Nussbaumer to @tuwien.at sharing insights from almost 40 years in #medicinalchemistry & #drugdiscovery. Thanks to GÖCH and @boehringerglobal.bsky.social RCV GmbH & Co KG. #chemistry_tuw
December 4, 2025 at 9:40 AM
medchemres.bsky.social
Access our December Issue of Med Chem Res 2025 - A Special Issue in Honor of Prof. George A. Garcia here: link.springer.com/journal/44/v...
#medicinalchemistry #naturalproducts #drugdiscovery #chemistry #MedChemRes #MedChemResearch #DMPK #rutgersmedchem #UMichmedchem
Cover for our December Issue of Med Chem Res 2025 - A Special Issue in Honor of Prof. George A. Garcia
November 28, 2025 at 3:31 PM
mlopes0811.bsky.social
Our new paper has been published: "Chiral Resolution, stereochemical assignment and correction of a cystic fibrosis-causing variant of Aryl-Triazolyl-methanol derivative" in Journal of Molecular Strucuture 🧑‍🔬🧬💊

#medicinalchemistry #drugdevelopment #cysticfibrosis

doi.org/10.1016/j.mo...
Redirecting
doi.org
November 24, 2025 at 12:18 PM
rscbmcs.bsky.social
*FREE CONFERENCE*

📣 Registration is now open for the BMCS Postgraduate Symposium XIX – Biological and Medicinal Chemistry Symposium for Postgraduates

📅 Thursday 8th January, 2026
📍 MIB Building, Manchester University
👉 www.rscbmcs.org/events/psxix/
#PHD #MedicinalChemistry #Biology #Conference
November 20, 2025 at 2:48 PM
purescience.news
Was King Tut’s Tomb Filled With Opiates? Yale Study Unlocks Ancient Secret #Science #Chemistry #MedicinalChemistry #KingTut #AncientEgypt #Opiates
Was King Tut’s Tomb Filled With Opiates? Yale Study Unlocks Ancient Secret
An ancient alabaster vase from Yale’s Babylonian Collection has revealed traces of opium, offering the strongest evidence yet of widespread opiate use in ancient Egypt. A recently analyzed alabaster...
purescience.news
November 18, 2025 at 3:30 AM
c-j-fisher.bsky.social
#Crystallography serves a crucial role in determining molecular structures, helping to resolve functional activities.

So-called structure-activity relationship (SAR) studies play a key part in understanding protein function and how to target them in #DrugDiscovery & #MedicinalChemistry.

(2/8) 🧪
November 14, 2025 at 6:47 PM
medchemres.bsky.social
Access our November Issue of Med Chem Res 2025 - A Special Issue in Honor of Prof. Margaret O. James here: link.springer.com/journal/44/v...
#medicinalchemistry #naturalproducts #drugdiscovery #chemistry #MedChemRes #MedChemResearch #DMPK #rutgersmedchem #UFmedchem
November 14, 2025 at 4:11 PM
purescience.news
After Decades, Scientists Have Finally Discovered Tylenol’s Secret Mechanism #Science #Chemistry #MedicinalChemistry #TylenolResearch #HealthScience
After Decades, Scientists Have Finally Discovered Tylenol’s Secret Mechanism
Scientists have discovered that acetaminophen doesn’t only work in the brain, it also blocks pain directly in nerve endings. Researchers at the Hebrew University of Jerusalem have found that acetaminophen...
purescience.news
November 13, 2025 at 8:27 PM
purescience.news
100x More Potent: Chemists Discover Powerful New Antibiotic “Hidden in Plain Sight” #Science #Chemistry #MedicinalChemistry #Antibiotics #ChemistryNews #HealthInnovation
100x More Potent: Chemists Discover Powerful New Antibiotic “Hidden in Plain Sight”
Researchers have discovered new intermediates in the methylenomycin pathway that are 100 times more active against drug-resistant Gram-positive bacteria. Chemists at the University of Warwick and Monash...
purescience.news
November 2, 2025 at 10:27 PM
brandonstieve.bsky.social
“ #PeriodicGraphics: Beyond flavor: Strange #spice science” — @cenmag.bsky.social

#Pharmacology #MedicinalChemistry #Biochemistry 🧪

cendigitalmagazine.acs.org/2025/10/13/p...
Periodic Graphics: Beyond flavor: Strange spice science
Chemical educator and Compound Interest blogger Andy Brunning cooks up some examples of spices doing more than flavoring our food
cendigitalmagazine.acs.org
November 1, 2025 at 2:58 PM
beilstein-institut.bsky.social
Discover the secrets of #cyclopropane and get the key insights needed to design the next generation of high-performance #pharmaceuticals 💊. 
👉 https://www.beilstein-journals.org/bjoc/articles/21/137?B=y
#polarity #DrugDesign #fluorination #MedicinalChemistry #BJOC 💎🔓
@uflabr.bsky.social
October 29, 2025 at 2:02 PM
brandonstieve.bsky.social
“How #AI is taking over every step of #DrugDiscovery” — @cenmag.bsky.social

#ComputationalChemistry #MedicinalChemistry

cendigitalmagazine.acs.org/2025/10/13/h...
How AI is taking over every step of drug discovery
Academic scientists and pharmaceutical companies alike are embracing artificial intelligence, even as questions linger about its value
cendigitalmagazine.acs.org
October 25, 2025 at 3:05 PM
purescience.news
This fragment-based drug discovery library is designed to be sociable #Science #Chemistry #MedicinalChemistry #DrugDiscovery #Pharmaceuticals #ChemistryInnovation
This fragment-based drug discovery library is designed to be sociable
Study targets a key bottleneck in hit to lead optimisation by designing fragments that are both structurally diverse and easy to elaborate
purescience.news
October 22, 2025 at 12:01 PM
purescience.news
A Common Pain Relief Drug May Have Anti-Cancer Properties #Science #HealthandMedicine #Oncology #PainRelief #CancerResearch #MedicinalChemistry
A Common Pain Relief Drug May Have Anti-Cancer Properties
Here's what we know.
purescience.news
October 17, 2025 at 7:45 AM
brainsbeesbikes.bsky.social
New collaborative study identifies 4-substituted phenylpyrazolidinone derivatives as potent inhibitors of Ku70/80-DNA-PK, a key enzyme in the DNA repair pathway.

🔗 doi.org/10.1039/d5md...

#MedicinalChemistry #DNARepair #Oncology #Pharmacology
October 15, 2025 at 2:23 AM
scholarai.bsky.social
This progress could lead to targeted therapies with fewer side effects, opening new avenues in disease treatment and personalized medicine. Inorganic chemistry's evolving role is crucial for innovative solutions in healthcare. #InorganicChemistry #MedicinalChemistry
October 14, 2025 at 5:58 PM
medchemres.bsky.social
Access our September Issue of Med Chem Res 2025 here: link.springer.com/journal/44/v...
#medicinalchemistry #naturalproducts #drugdiscovery #chemistry #MedChemRes #MedChemResearch #DMPK #rutgersmedchem
October 1, 2025 at 2:18 PM
medchemres.bsky.social
Access our October Issue of Med Chem Res 2025 here: link.springer.com/journal/44/v...
#medicinalchemistry #naturalproducts #drugdiscovery #chemistry #MedChemRes #MedChemResearch #DMPK #rutgersmedchem
October 1, 2025 at 2:05 PM
fluorochemltd.bsky.social
Cereblon (CRBN) ligands the most extensively used ligase recruiters in targeted protein degradation. The CRL4 CRBN E3 ligase complex is recruited to tag proteins for ubiquitination & degradation. 🧪
#TargetedMedicine #MedicinalChemistry #ProteinDegradation #PharmaResearch #TranslationalResearch #TPD
September 25, 2025 at 10:05 AM
rscbmcs.bsky.social
Kicking off #CamMedChem25 in windy Cambridge! 🌬️

Delegates are exploring AI in Chemistry, interactive drug discovery workshops & first disclosures from AstraZeneca, Novartis, Gilead & more. Exciting days ahead! #MedicinalChemistry
September 15, 2025 at 2:06 PM