Excited for our minisymposia session “Physical Cell Biology from Molecules to Organisms” at #CellBio25 (www.ascb.org/cellbio2025/). Do you work in #DevBio #StemCell #Biophysics #MechaBio #StructuralBio? Then, please consider submitting your work before the September 3rd deadline (shorturl.at/Y8jPq).
Cell Bio 2023-An ASCB|EMBO Meeting
Network, learn, and collaborate with top cell biologists from around the globe.
www.ascb.org
August 4, 2025 at 8:28 AM
Excited for our minisymposia session “Physical Cell Biology from Molecules to Organisms” at #CellBio25 (www.ascb.org/cellbio2025/). Do you work in #DevBio #StemCell #Biophysics #MechaBio #StructuralBio? Then, please consider submitting your work before the September 3rd deadline (shorturl.at/Y8jPq).
SBGrid's eLife paper received a citation in June from Jeffrey Holt from @bostonchildrens.bsky.social along w/ Tianmin Fu of The Ohio State University, Marcos Sotomayor from University of Chicago, & Shaun Rawson from @harvardmed.bsky.social
Read more here: buff.ly/9dyEZEw
#SBGrid #StructuralBio
Read more here: buff.ly/9dyEZEw
#SBGrid #StructuralBio
July 10, 2025 at 4:07 PM
SBGrid's eLife paper received a citation in June from Jeffrey Holt from @bostonchildrens.bsky.social along w/ Tianmin Fu of The Ohio State University, Marcos Sotomayor from University of Chicago, & Shaun Rawson from @harvardmed.bsky.social
Read more here: buff.ly/9dyEZEw
#SBGrid #StructuralBio
Read more here: buff.ly/9dyEZEw
#SBGrid #StructuralBio
Don't miss the 2025 Computational Structural Virology Symposium
🗓️ Aug 4 | 🕔 5–10pm CEST | on Zoom
🎤 Philippe Le Mercier @viralzone.bsky.social will present "Structural Modeling Reveals Hidden Functions in Viral Proteins".
📌 Register: forms.gle/CNiqskMwQEuV...
#Virology #SciSymposium #StructuralBio
🗓️ Aug 4 | 🕔 5–10pm CEST | on Zoom
🎤 Philippe Le Mercier @viralzone.bsky.social will present "Structural Modeling Reveals Hidden Functions in Viral Proteins".
📌 Register: forms.gle/CNiqskMwQEuV...
#Virology #SciSymposium #StructuralBio
July 2, 2025 at 4:28 PM
Don't miss the 2025 Computational Structural Virology Symposium
🗓️ Aug 4 | 🕔 5–10pm CEST | on Zoom
🎤 Philippe Le Mercier @viralzone.bsky.social will present "Structural Modeling Reveals Hidden Functions in Viral Proteins".
📌 Register: forms.gle/CNiqskMwQEuV...
#Virology #SciSymposium #StructuralBio
🗓️ Aug 4 | 🕔 5–10pm CEST | on Zoom
🎤 Philippe Le Mercier @viralzone.bsky.social will present "Structural Modeling Reveals Hidden Functions in Viral Proteins".
📌 Register: forms.gle/CNiqskMwQEuV...
#Virology #SciSymposium #StructuralBio
Beyond high affinity binders.
Sort of current dream in #structuralbio: A ligand binding to a protein with high affinity at a single site.
As a microscopist, I'd rather be interested in cooperative avidity binding (2+ low affinity binding sites at the target protein).
Are there tools to design that?
Sort of current dream in #structuralbio: A ligand binding to a protein with high affinity at a single site.
As a microscopist, I'd rather be interested in cooperative avidity binding (2+ low affinity binding sites at the target protein).
Are there tools to design that?
July 1, 2025 at 12:32 AM
Beyond high affinity binders.
Sort of current dream in #structuralbio: A ligand binding to a protein with high affinity at a single site.
As a microscopist, I'd rather be interested in cooperative avidity binding (2+ low affinity binding sites at the target protein).
Are there tools to design that?
Sort of current dream in #structuralbio: A ligand binding to a protein with high affinity at a single site.
As a microscopist, I'd rather be interested in cooperative avidity binding (2+ low affinity binding sites at the target protein).
Are there tools to design that?
New review in Drug Discovery Today:
Modeling protein–protein interactions in the AI era
🔗 doi.org/10.1016/j.dr...
AI is shiny. Biology is messy — flexibility, disorder, weak signals, big complexes.
We map what’s working, what isn’t, and what’s next.
#AlphaFold #StructuralBio #CompBio #DrugDiscovery
Modeling protein–protein interactions in the AI era
🔗 doi.org/10.1016/j.dr...
AI is shiny. Biology is messy — flexibility, disorder, weak signals, big complexes.
We map what’s working, what isn’t, and what’s next.
#AlphaFold #StructuralBio #CompBio #DrugDiscovery
Redirecting
doi.org
May 30, 2025 at 8:04 PM
New review in Drug Discovery Today:
Modeling protein–protein interactions in the AI era
🔗 doi.org/10.1016/j.dr...
AI is shiny. Biology is messy — flexibility, disorder, weak signals, big complexes.
We map what’s working, what isn’t, and what’s next.
#AlphaFold #StructuralBio #CompBio #DrugDiscovery
Modeling protein–protein interactions in the AI era
🔗 doi.org/10.1016/j.dr...
AI is shiny. Biology is messy — flexibility, disorder, weak signals, big complexes.
We map what’s working, what isn’t, and what’s next.
#AlphaFold #StructuralBio #CompBio #DrugDiscovery
SBGrid's eLife paper received a citation from Dirk Slotboom of University of Groningen in Nature Magazine Communications: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Read more here: https://buff.ly/3zd6S7Q
#SBGrid #ScienceMatters #structuralbio
Read more here: https://buff.ly/3zd6S7Q
#SBGrid #ScienceMatters #structuralbio
Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2 - Nature Communications
ASCT2 is a Na+-dependent obligatory amino acid exchanger. Here, the authors untangle the structural basis of the exchange mechanism in ASCT2, revealing that structural rigidity and a high-affinity…
buff.ly
September 22, 2024 at 4:00 PM
SBGrid's eLife paper received a citation from Dirk Slotboom of University of Groningen in Nature Magazine Communications: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2.
Read more here: https://buff.ly/3zd6S7Q
#SBGrid #ScienceMatters #structuralbio
Read more here: https://buff.ly/3zd6S7Q
#SBGrid #ScienceMatters #structuralbio