#cystine
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pnasnexus.org
Pheomelanin, the pigment that creates orange feathers and redheaded humans, is associated with a high risk of melanoma—so why does it persist? A study in zebra finches finds a role for the pigment in neutralizing toxic cystine. In PNAS Nexus: https://ow.ly/7zTv50XVy6A
Male (left) and female (right) zebra finches. The orange feathers displayed by the male are colored by the pigment pheomelanin, which is also present in human skin and red hair. Pheomelanin is associated with an increased risk of melanoma, but also exerts a beneficial physiological function consisting in the avoidance of toxicity that an excess of the amino acid cysteine in the diet may cause.
January 12, 2026 at 8:30 PM
ginadenicola.bsky.social
Using U¹³C₆-cystine infusion, we show tail vein achieves robust steady-state labeling of cystine and downstream metabolites (glutathione, taurine pathways) without the supraphysiologic tracer accumulation seen with jugular infusion.
January 6, 2026 at 8:11 PM
bediko.de
In Fleisch stecken über 20 chemische Stoffe. Was ist daran jetzt gesund?
INGREDIENTS: WATER (50.2%); AMINO ACIDS (24.0%) [GLUTAMIC ACID (15.1%), ASPARTIC ACID (9.1%), LYSINE (8.4%), LEUCINE (7.9%), GLYCINE (7.3%), ARGININE (6.7%), ALANINE (6.5%), PROLINE (5.4%), VALINE (5%), ISOLEUCINE (4.5%), SERINE (4.1%), PHENYLALANINE (4%), THREONINE (3.9%), HISTIDINE (3.3%), TYROSINE (3.1%), METHIONINE (2.6%), HYDROXYPROLINE (1.7%), CYSTINE (1%), TRYPTOPHAN (0.5%)]; FATTY ACIDS (15.9%) [OMEGA-7 TRANS FAT VACCENIC ACID (45.1%), PALMITIC ACID (25.2%), STEARIC ACID (14%), OMEGA-7 PALMITOLEIC ACID (4.3%), MYRISTIC ACID (3.4%), OMEGA-6 LINOEIC ACID (2.7%), MARGARIC ACID (1.3%), MYRISTOLEIC ACID (0.9%), OMEGA-9 MARGAROLEIC ACID (0.9%), PENTADECANOIC ACID (0.6%), OMEGA-3 ALPHA-LINOLENIC ACID (0.7%), OMEGA-7 PAULLINIC ACID (NON-CALORIC AND NOT DIGESTIBLE, 0.4%), OMEGA-6 ARACHIDONIC ACID (0.3%), LAURIC ACID (0.1%), ARACHIDIC ACID (0.1%), OMEGA-6 GAMMA-LINOLENIC ACID (0.1%)]; ANTIOXIDANT (E306), PHYLLOQUINONE, EMULSIFIER (E1001), ACIDITY REGULATOR (E375); COLORS (E101 YELLOW); PYRIDOXINE, FOLATE, PANTOTHENIC ACID, CHOLESTEROL; UNIQUE BEEF FLAVOR (12-METHYLTRIDECANAL); BEEF FLAVORS (PYRROLIDONE, HYPOXANTHINE, ANSERINE, CARNOSINE, INOSINE, GUANOSINE, RIBOSE); OTHER FLAVORS (OCT-1-EN-3-OL (MUSHROOM FLAVOR COMPOUND PRODUCED DURING THE AGEING PROCESS OF BEEF), OCTANAL, NONANAL, (E,E)-2,4-DECADIENAL, METHANETHIOL, 2-FURFURYLTHIOL, 3-MERCAPTO-2-PENTANONE, 4-HYDROXY-2,5-DIMETHYL-3-(2H)-FURANONE, 3-MERCAPTO-2-METHYLPENTAN-1-OL, PENTANAL, HEXANAL, HEPTANAL, METHIONAL, NONA-2(E)-ENAL, DECA-2(E), 4(E)-DIENAL, BUTANOIC ACID, HEXANOIC ACID, DELTA-NONALACTONE, DECAN-2-ONE, 3-HYDROXY-2-BUTANONE, 2,3-OCTANEDIONE, 2-PENTYL FURAN, 2-METHYL-3-[METHYLTHIO]FURAN, 4-HYDROXY-5-METHYL-3(2H)-FURANONE (HMF), METHYLPYRAZINE, 2,5-DIMETHYLPYRAZINE, LACTIC ACID, FLAVOR ENHANCERS (E338, E630), BIS(2-METHYL-3-FURYL) DISULFIDE, 2-METHYL-3-FURANTHIOL (CHICKEN FLAVOR)), ANABOLIC STEROID (TRENBOLONE ACETATE); OTHER GROWTH HORMONES (PROGESTERONE, TESTOSTERONE, OESTROGEN, ZERANOL); ANTIBIOTIC (OXY…
January 6, 2026 at 1:18 PM
vjsanchez.bsky.social
Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma www.nature.com/articles/s41... 🧪 #PancreaticCancer
Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma - Nature Communications
Cystine levels in pancreatic ductal adenocarcinoma (PDAC) tumour microenvironment are deficient, despite its crucial role for cancer cell maintenance. Here, the authors show that adaptation to cystine...
www.nature.com
January 2, 2026 at 6:30 PM
ie-news.bsky.social
L-cystine alleviates necrotizing enterocolitis by regulating ferroptosis and Th17 cell differentiation via the IL-6/STAT3 pathway

https://www.europesays.com/ie/257278/

Roberts, A. G., Younge, N. & Greenberg, R. G. Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and…
L-cystine alleviates necrotizing enterocolitis by regulating ferroptosis and Th17 cell differentiation via the IL-6/STAT3 pathway - Ireland
Roberts, A. G., Younge, N. & Greenberg, R. G. Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and Prevention. Paediatr. Drugs
www.europesays.com
December 30, 2025 at 3:30 AM
swilua.bsky.social
*giving advice to my children*

If you’re going to drink, remember your liver can only process one drink per hour & while supplements like L-cystine can help, ultimately what you really need to do is just STAY TF OFF YOUR PHONE because no one knows your tweets are drunk tweets, they think it’s YOU
December 12, 2025 at 11:31 PM