Lightnews — Scholar-powered news

Gina DeNicola @ginadenicola.bsky.social · 15d

The best compliment 😁

Daniel Gorelick @danielgorelick.bsky.social · 15d

I now like metabolomics thanks to @ginadenicola.bsky.social interesting talk! Thanks for visiting MCB at Baylor College of Medicine

2

Reposted by Gina DeNicola

Katsu Funai @katsufunai.bsky.social · Aug 27

We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social

Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064

The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...

www.nature.com

27 24

Reposted by Gina DeNicola

Suayb Üstün @suaybuestuen.bsky.social · Aug 22

Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details!

jobs.ruhr-uni-bochum.de/jobposting/f...

W1TTW2 Professorship in Membrane Biology (m/f/d)

jobs.ruhr-uni-bochum.de

1 60 33

Reposted by Gina DeNicola

Soni Lacefield @lacefieldlab.bsky.social · Aug 27

My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

1 56 53

Reposted by Gina DeNicola

Johanna Joyce @johannajoyce.bsky.social · Aug 21

A wonderful new opportunity - for both Rising Stars and established Research Leaders - to open a research lab in Ireland 🇮🇪🧪

Up to 3.25 million euro in support 🤩

#GlobalTalentIreland #Research #Ireland

Research Ireland @researchireland.ie · Aug 21

Research Ireland, on behalf of @deptoffhed.bsky.social, have launched Global Talent Ireland - a new initiative to attract exceptional mid-career and established researchers from across the globe to Ireland.

For more information visit:

www.researchireland.ie/funding/global-talent-ireland/

Global Talent Ireland Decorative Graphic

6 8

Reposted by Gina DeNicola

Karolinska Institutet @ki.se · Aug 18

Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...

56 51

Reposted by Gina DeNicola

Katsu Funai @katsufunai.bsky.social · Jul 21

We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social

Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah | 674355

The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...

jobs.sciencecareers.org

32 29

Gina DeNicola @ginadenicola.bsky.social · Aug 12

Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here: moffitt-cancer-center-careers.hctsportals.com/jobs/1883440...

Tenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cancer Center CareersTenure-Earning Assistant Member Metabolism & Physiology Faculty in Tampa, FL - Moffitt Cance...

Working at Moffitt Cancer Center is both a career and a mission. All employees are dedicated to patient care, research and education to advance our fight against this disease.

moffitt-cancer-center-careers.hctsportals.com

6 7

Reposted by Gina DeNicola

Brent Stockwell @brentstockwell.bsky.social · Jul 31

Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social

9 25

Gina DeNicola @ginadenicola.bsky.social · Jul 27

Hot science and hot temperatures at the FASEB Ferroptosis conference start tonight. Seriously the highs are 110F here 🥵 but it's beautiful!

1 14

Reposted by Gina DeNicola

Mara Sherman @marasherman.bsky.social · Jul 24

To distract from your own stress responses (!!!), check out this awesome new study from the Commisso lab linking metabolic stress to regulation of the pancreatic tumor microenvironment! ✨

Cosimo Commisso @cosimocommisso.bsky.social · Jul 24

Excited to share work published in @cp-cancercell.bsky.social by @yijuan.bsky.social showing that macropinocytosis inhibition drives myCAF-to-iCAF conversion, enhancing therapeutic responses in pancreatic cancer. Thank you to our collaborators that contributed! www.sciencedirect.com/science/arti...

Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) tumors are glutamine deficient, and both tumor cells and cancer-associated fibroblasts (CAFs) rely on this ami…

www.sciencedirect.com

2 9

Reposted by Gina DeNicola

Elizabeth McKenna @elizsmckenna.bsky.social · Jul 22

It's my first #newPI roll call on BlueSky! Calling all new #cancer PIs who just started or who are about to start their labs! Please say hi and what you work on so I can follow you if I don't already! 😃

11 27

Reposted by Gina DeNicola

Jeremy Berg @jeremymberg.bsky.social · Jul 12

IMPORTANT IMPORTANT IMPORTANT IMPORTANT

Please watch the workshop video and COMMENT by 5:00 Monday 7/14

This is the source of the "no more model organism only grants in NIH-funded research" decree.

@LaBonneLaB @labonnelab.bsky.social · Jul 11

Dear all, PLEASE add comments on the importance of model organism research at this link:

4 120 100

Gina DeNicola @ginadenicola.bsky.social · Jun 10

New work from @karrethlab.bsky.social!

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · Jun 10

FRA1 drives melanoma metastasis through an actionable transcriptional network https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1

1 2

Reposted by Gina DeNicola

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · Jun 10

FRA1 drives melanoma metastasis through an actionable transcriptional network https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1

1 1

Reposted by Gina DeNicola

Christian Frezza @frezzalab.bsky.social · May 21

Unravelling cysteine-deficiency-associated rapid weight loss

www.nature.com/articles/s41...

Unravelling cysteine-deficiency-associated rapid weight loss - Nature

Conditional cysteine restriction in mice causes substantial weight loss, exceeding that seen with essential amino acid restriction, by activating the integrated stress and oxidative stress respon...

www.nature.com

5 15

Gina DeNicola @ginadenicola.bsky.social · May 21

Great work by @rushika-perera.bsky.social!

Christian Frezza @frezzalab.bsky.social · May 21

PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer

www.nature.com/articles/s41...

Massive congratulations to @rushika-perera.bsky.social Lab!!

PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer - Nature

PCSK9 regulates low density lipoprotein-cholesterol import and determines organ preference of metastatic pancreatic ductal adenocarcinoma, with PCSK9-low cells metastasizing to the liver and PCSK9-hig...

www.nature.com

1 2 11

Reposted by Gina DeNicola

Jeremy Berg @jeremymberg.bsky.social · May 20

REMINDER.....REMINDER......REMINDER

3 DAYS LEFT TO COMMENT ON SCHEDULE F

1/n

gumball and anais from the amazing world of gumball are sitting at a table

ALT: gumball and anais from the amazing world of gumball are sitting at a table

media.tenor.com

3 87 89

Reposted by Gina DeNicola

Journal of Cell Science @jcellsci.bsky.social · May 20

Our latest ‘Cell Scientist to Watch’ is Samantha Lewis. We caught up with Samantha to discuss her career path, the challenges for working on the ‘neglected’ mitochondrial genome and the exciting new frontiers in mitochondrial research.
journals.biologists.com/jcs/article/...
#JCSMitoSI

2 9

Gina DeNicola @ginadenicola.bsky.social · May 12

So excited for this!

FASEB @faseborg.bsky.social · May 10

Abstracts are being accepted for #FOLSCR, a brand-new conference exploring a new form of cell death. With @ginadenicola.bsky.social and @brentstockwell.bsky.social, this may be one of FASEB's biggest new conferences. Submit your research by June 1 and save your space: buff.ly/HB3PDmS

2 3

Gina DeNicola @ginadenicola.bsky.social · May 12

MALDI imaging of lipids, metabolites and glycans all on the same section! From Ramon Sun and colleagues. www.nature.com/articles/s41...

Spatial mapping of the brain metabolome lipidome and glycome - Nature Communications

Clarke et al. presents a framework for spatial analysis of the metabolome, lipidome, and glycome from a single tissue section using mass spectrometry imaging. Applying this approach, they revealed reg...

www.nature.com

5 21

Reposted by Gina DeNicola

Journal of Cell Science @jcellsci.bsky.social · May 9

In their Tools & Resources article, Corey Cunningham @cnfxc.bsky.social Jared Rutter @rutterlab.bsky.social @uofubiochem.bsky.social & team present their dual-purification system to isolate mitochondrial subpopulations.
journals.biologists.com/jcs/article/...
#JCSMitoSI #OpenAccess #Mitochondria

Figure showing that mitochondrial subpopulations proximal to endosomes and lipid droplets have similar proteomes, but both are significantly different from an average mitochondrial proteome.

1 3

Gina DeNicola @ginadenicola.bsky.social · May 8

I am so very proud of Amanda for what she has accomplished in this study, of manuscript she wrote, and of her fearlessness in science. She is a superstar 🌟 I would also like to give a shoutout to our newest lab member Basma Yasseen who carried the revisions over the finish line 💪

3

Gina DeNicola @ginadenicola.bsky.social · May 8

Now came the real surprise! Tumors could form lacking both GSR and TXNRD1. Cytosolic disulfide reductase activity is necessary for the reduction of protein disulfides, cystine, and other molecules so how this is possible is still a mystery - and the focus on ongoing work!

1 2

Gina DeNicola @ginadenicola.bsky.social · May 8

Amanda found GSR deletion impaired tumor initiation, regardless of NRF2 status, while TXNRD1 deletion impaired progression to the adenoma stage specifically in NRF2 mutant tumors. This suggested they had non-overlapping roles at these stages.

1 1