#OpenBind has installed three new Crystal Shifter instruments to support Diamond Light Source’s #XChem #FragmentScreening and help drive the next generation of ML‑powered structure‑based #drug design. https://loom.ly/RRLB3V0),
January 16, 2026 at 12:10 PM
#OpenBind has installed three new Crystal Shifter instruments to support Diamond Light Source’s #XChem #FragmentScreening and help drive the next generation of ML‑powered structure‑based #drug design. https://loom.ly/RRLB3V0),
At #CCP4 Study Weekend, Jasmin Aschenbrenner showcased #OpenBind - an initiative creating high-quality #FragmentScreening data at Diamond to power next-gen machine learning for #DrugDiscovery.
Learn more about this initiative:
Website: http://www.openbind.org
Bluesky: @openbind.bsky.social
Learn more about this initiative:
Website: http://www.openbind.org
Bluesky: @openbind.bsky.social
January 13, 2026 at 9:04 AM
At #CCP4 Study Weekend, Jasmin Aschenbrenner showcased #OpenBind - an initiative creating high-quality #FragmentScreening data at Diamond to power next-gen machine learning for #DrugDiscovery.
Learn more about this initiative:
Website: http://www.openbind.org
Bluesky: @openbind.bsky.social
Learn more about this initiative:
Website: http://www.openbind.org
Bluesky: @openbind.bsky.social
Attending #CCP4? Don’t miss Day 2 at 16:00–16:30! Discover how Diamond’s #FragmentScreening facility accelerates early-stage drug discovery. Hear Ailsa Powell share how XChem speeds structural insights from concept to candidate. https://loom.ly/mZKk5ys
January 7, 2026 at 5:04 PM
Attending #CCP4? Don’t miss Day 2 at 16:00–16:30! Discover how Diamond’s #FragmentScreening facility accelerates early-stage drug discovery. Hear Ailsa Powell share how XChem speeds structural insights from concept to candidate. https://loom.ly/mZKk5ys
By integrating cutting-edge technologies and workflows, XFBLD-Platform addresses key challenges in fragment-based lead discovery, such as throughput, accuracy and data management #FragmentBasedLeadDiscovery #ProteinCrystallography #FragmentScreening doi.org/10.1107/S205...
September 9, 2025 at 2:46 PM
By integrating cutting-edge technologies and workflows, XFBLD-Platform addresses key challenges in fragment-based lead discovery, such as throughput, accuracy and data management #FragmentBasedLeadDiscovery #ProteinCrystallography #FragmentScreening doi.org/10.1107/S205...
Excited to be in Ponzan, Poland🤍❤️ at the European Crystallographic Meeting #ECM35 -- jointly hosted by Lviv, Ukraine💙💛!!
Presenting my work as part of @pdbeurope.bsky.social on improvements for data capture for fragment screening experiments.
#FragmentScreening
Presenting my work as part of @pdbeurope.bsky.social on improvements for data capture for fragment screening experiments.
#FragmentScreening
A poster from the PDBe team viewable Thursday & Friday at #ECM35
🧪 MS6_P7 - Building a FAIR Repository for Fragment-Based Screening Campaigns - Presented by Genevieve Evans
All ECM poster titles & abstracts available here:
🔗 ecm35.ecanews.org/poster-hiper...
#Biology #Chemistry
🧪 MS6_P7 - Building a FAIR Repository for Fragment-Based Screening Campaigns - Presented by Genevieve Evans
All ECM poster titles & abstracts available here:
🔗 ecm35.ecanews.org/poster-hiper...
#Biology #Chemistry
August 28, 2025 at 6:34 AM
Excited to be in Ponzan, Poland🤍❤️ at the European Crystallographic Meeting #ECM35 -- jointly hosted by Lviv, Ukraine💙💛!!
Presenting my work as part of @pdbeurope.bsky.social on improvements for data capture for fragment screening experiments.
#FragmentScreening
Presenting my work as part of @pdbeurope.bsky.social on improvements for data capture for fragment screening experiments.
#FragmentScreening
Liqing Huang et al.: XFBLD-Platform: a crystallographic fragment-screening platform at Shanghai Synchrotron Radiation Facility ##FragmentBasedLeadDiscovery##ProteinCrystallography##FragmentScreening... ##IUCrhttps://journals.iucr.org/paper?S2059798325006801
XFBLD-Platform: a crystallographic fragment-screening platform at Shanghai Synchrotron Radiation Facility
A crystallographic fragment-screening platform, referred to as the XFBLD-Platform, developed at Shanghai Synchrotron Radiation Facility accelerates fragment-based lead discovery through an integrated high-throughput workflow for structure-based drug development.
journals.iucr.org
August 12, 2025 at 12:00 AM
Liqing Huang et al.: XFBLD-Platform: a crystallographic fragment-screening platform at Shanghai Synchrotron Radiation Facility ##FragmentBasedLeadDiscovery##ProteinCrystallography##FragmentScreening... ##IUCrhttps://journals.iucr.org/paper?S2059798325006801
**Postdoc Research Position** #available in "AI/ML Approaches to Precision Drug Discovery" @iqccudg.bsky.social @univgirona.bsky.social
Interested candidates please contact: [email protected]
#fragmentscreening #generativechemistry #drugresistance #precisionmedicine
Interested candidates please contact: [email protected]
#fragmentscreening #generativechemistry #drugresistance #precisionmedicine
June 5, 2025 at 1:38 PM
**Postdoc Research Position** #available in "AI/ML Approaches to Precision Drug Discovery" @iqccudg.bsky.social @univgirona.bsky.social
Interested candidates please contact: [email protected]
#fragmentscreening #generativechemistry #drugresistance #precisionmedicine
Interested candidates please contact: [email protected]
#fragmentscreening #generativechemistry #drugresistance #precisionmedicine
Three active-site fragments obtained from a cystallographic fragment screen of Bacillus subtilis CdaA were used in an silico drug-repurposing screen that identified a drug with inhibitory potential #CdaA #CyclicDiAMP #FragmentScreening t.co/heUH3ZLcj1
September 11, 2024 at 3:03 PM
Three active-site fragments obtained from a cystallographic fragment screen of Bacillus subtilis CdaA were used in an silico drug-repurposing screen that identified a drug with inhibitory potential #CdaA #CyclicDiAMP #FragmentScreening t.co/heUH3ZLcj1
Tim Garbers et al.: Crystallographic fragment screen of the c-di-AMP-synthesizing enzyme CdaA from Bacillus subtilis ##CdaA##CyclicDiAMP##FragmentScreening@unigoettingen...##IUCrhttps://journals.iucr.org/paper?S2053230X24007039
Crystallographic fragment screen of the c-di-AMP-synthesizing enzyme CdaA from Bacillus subtilis
The crystal structure determination of CdaA enzymes from Streptococcus pneumoniae, Bacillus subtilis and Enterococcus faecium is reported. Additionally, the structural results of a fragment screen of B. subtilis CdaA are presented, along with a subsequent in silico drug-repurposing screen conducted using the OpenEye suite.
journals.iucr.org
August 24, 2024 at 12:00 AM
Tim Garbers et al.: Crystallographic fragment screen of the c-di-AMP-synthesizing enzyme CdaA from Bacillus subtilis ##CdaA##CyclicDiAMP##FragmentScreening@unigoettingen...##IUCrhttps://journals.iucr.org/paper?S2053230X24007039
A crystallographic fragment screen against CdaA from Listeria monocytogenes provides potential starting points for the development of antibiotics against several CdaA-dependent bacteria. #FragmentScreening #CdaA #CyclicDiAMP t.co/Xg5ZpZjaJH
May 21, 2024 at 2:23 PM
A crystallographic fragment screen against CdaA from Listeria monocytogenes provides potential starting points for the development of antibiotics against several CdaA-dependent bacteria. #FragmentScreening #CdaA #CyclicDiAMP t.co/Xg5ZpZjaJH
The new HEIDI webpage enables real-time tracking of data-processing results at the Swiss Light Souce, offering a dynamic and user-focused approach to project management #DataManagement #FragmentScreening #HighThroughputCrystallography
t.co/UKoBHnGsjC
t.co/UKoBHnGsjC
May 16, 2024 at 1:27 PM
The new HEIDI webpage enables real-time tracking of data-processing results at the Swiss Light Souce, offering a dynamic and user-focused approach to project management #DataManagement #FragmentScreening #HighThroughputCrystallography
t.co/UKoBHnGsjC
t.co/UKoBHnGsjC