#translationalmedicine
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doctorsivamd.bsky.social
Outstanding Grand Rounds with Dr. Michele Curatolo on human-centric molecular pain neuroscience. A rigorous, integrative framework linking pain neurobiology to clinical phenotypes and potential treatment strategies.

#PainResearch #Neuroscience #TranslationalMedicine
February 5, 2026 at 3:41 PM
longevitytech.bsky.social
PMD trial ties functional measures with NAD⁺ and redox biomarkers, offering a pragmatic view of mitochondrial modulation.

longevity.technology/news/mitocho...

#longevity #mitochondria #clinicaltrials #neurodegeneration #biotechnews #translationalmedicine
January 30, 2026 at 6:30 PM
sigtrans-sttt.bsky.social
Lung cancer research highlights from Signal Transduction and Targeted Therapy, featuring advances from molecular pathology to clinical trials and therapeutic resistance.
www.nature.com/sigtrans/
#LungCancer #CancerResearch #SignalTransduction #TranslationalMedicine
January 27, 2026 at 10:31 AM
disabled-world.com
#TranslationalMedicine: Bridging Research and Real Care - How #translational #medicine bridges research and real-world care, improving #health outcomes for #seniors and people with #disabilities through innovation - www.disabled-world.com/disability/p...
Translational Medicine: Bridging Research and Real Care
Discover how translational medicine bridges research and real-world care, improving health outcomes for seniors and people with disabilities through innovation.
www.disabled-world.com
January 24, 2026 at 5:10 PM
eatris.bsky.social
Every quarter, we spotlight peer-reviewed publications that cite or involve EATRIS-supported research. The publications from October to December 2025 are now available!

👉 Browse the full list: https://eatris.eu/publications-citing-eatris

#ResearchImpact #TranslationalMedicine
January 20, 2026 at 7:31 AM
genesndiseases.bsky.social
Boosting mitochondrial biogenesis may offer a powerful strategy to combat acute kidney injury (AKI)—current insights and future therapeutic directions.
#AKI #Mitochondria #RenalInjury #KidneyResearch #Translationalmedicine
www.sciencedirect.com/science/arti...
January 19, 2026 at 11:07 AM
theinnovation.bsky.social
While Piezo1 was constitutively expressed and dispensable for chronic itch in the MC903-induced atopic dermatitis (AD) model, Piezo2 expression was markedly upregulated in keratinocytes of lesional AD skin.
doi.org/10.59717/j.x...
#atopicdermatitis #TranslationalMedicine #skinhealth
January 10, 2026 at 5:57 AM
switzerlandomics.bsky.social
New pre-print. Based on the open-source evidence standard 🇨🇭

www.medrxiv.org/content/10.6...

Demo and R, macOS, Linux software: switzerlandomics.ch/technologies...

#genetics #genomics #wgs #raredisease #ppi #ppie #translationalmedicine #precisionmedicine
A Bayesian model for quantifying genomic variant evidence sufficiency in Mendelian disease
Summary Clinical genomic interpretation depends on heterogeneous evidence checks that vary across institutions and pipelines. This variation prevents evidence from being compared or verified in a reli...
www.medrxiv.org
December 23, 2025 at 2:26 PM
prof-clark.bsky.social
A first-in-class nanobody gene therapy enables sustained, intraocular inhibition of complement C3, significantly suppressing pathological neovascularization. #GeneTherapy #AMD #Complement #Nanobodies #Biotech #VisionScience #TranslationalMedicine buff.ly/JaWxxmB
Nanobody-based gene therapy targeting complement component C3 reduces choroidal neovascularization in mice - PubMed
Wet age-related macular degeneration (wAMD) is a leading cause of vision loss and is characterized by choroidal neovascularization (CNV). Current CNV management requires multiple treatments and lacks…
buff.ly
December 23, 2025 at 10:01 AM
swog.org
Our #TranslationalMedicine Link of the Week, chosen by @swog.org's Lee Ellis, MD, & Jimmy Rae, PhD:
FDA–AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Optimized Dosages for Registrational Trials
doi.org/10.1158/1078...
December 19, 2025 at 4:26 PM
positron96.bsky.social
#Health #HealthEquity #PersonalizedMedicine #PrecisionMedicine #Healthcare #Equity #GlobalHealth #HealthPolicy #DigitalHealth #HealthcareInnovation #HealthInnovation #PublicHealth #GlobalSouth #TranslationalMedicine #UniversalHealth #UniversalHealthcare
December 16, 2025 at 2:03 AM
csbj.org
🔗 Metabolic phenotypes: Molecular bridges between health homeostasis and disease imbalance. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#MetabolicPhenotyping #Metabolomics #PrecisionMedicine #BiomarkerDiscovery #TranslationalMedicine
Metabolic phenotypes: Molecular bridges between health homeostasis and disease imbalance. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.057
November 30, 2025 at 9:59 PM
swog.org
Our #TranslationalMedicine Link of the Week, chosen by @swog.org's Lee Ellis, MD, & Jimmy Rae, PhD:
CAR-T Cells in Solid Tumors: Challenges and Breakthroughs
doi.org/10.1016/j.xc...
November 28, 2025 at 5:51 PM
swog.org
Our #TranslationalMedicine Link of the Week, chosen by @swog.org's Lee Ellis, MD, & Jimmy Rae, PhD:
Bispecific Antibodies and Nanotechnology: A Strategic Alliance in Cancer Immunotherapy
doi.org/10.1186/s129...
Bispecific antibodies and nanotechnology: a strategic alliance in cancer immunotherapy - Molecular Cancer
Bispecific antibodies (bsAbs), designed to recognize two distinct antigens or epitopes, enable innovative mechanisms of action for emerging generations of cancer immunotherapies. Despite their potenti...
doi.org
November 21, 2025 at 6:01 PM
swog.org
Our #TranslationalMedicine Link of the Week, chosen by @SWOG's @recnac1 & Jimmy Rae, PhD:
Targeting DNA Repair Mechanisms in Cancer Therapy: The Role of Small Molecule DNA Repair Inhibitors
academic.oup.com/narcancer/ar...
SWOG TM Link of the Week
November 14, 2025 at 6:26 PM
eatris.bsky.social
EATRIS Scientific Director Toni Andreu joined the LifeArc Strategic Advisory Board meeting in London this week.

A great example of shared efforts in #RareDiseases and #TranslationalMedicine to improve patient access to new therapies.

🔗 https://loom.ly/Oh4OWUI
November 11, 2025 at 12:19 PM
swog.org
Our #TranslationalMedicine Link of the Week, chosen by @swog.org's Lee Ellis, MD, & Jimmy Rae, PhD:
WNT Signaling in Cancer: Molecular Mechanisms and Potential Therapies
doi.org/10.1186/s435...
WNT signaling in cancer: molecular mechanisms and potential therapies - Molecular Biomedicine
The WNT signaling pathway, a fundamental molecular network regulating cell proliferation, differentiation, and stemness, plays a critical role in tumorigenesis, cancer progression, and therapeutic res...
doi.org
November 7, 2025 at 5:01 PM
hemehub.bsky.social
Facts about Hemophilia A:

A concise overview of the mechanisms that link F8 gene mutations to clinical phenotype and disease severity.

#HemophiliaA #FactorVIII #BleedingDisorders #Hematology #RareDiseases #Coagulation #GeneTherapy #ClinicalTrials #TranslationalMedicine #BloodDisorders
November 6, 2025 at 1:11 AM
cvctforum.bsky.social
Join us for ample discussion on how to bridge the gap from concept to clinic: www.globalcvctforum.com/scientific-p...

#CKLM #RNAtherapeutics #CardioInnovation #TranslationalMedicine #CVCT
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
November 5, 2025 at 4:51 PM
eatris.bsky.social
Every quarter, we spotlight peer-reviewed publications that cite or involve EATRIS-supported research. The publications from July to September 2025 are now available!

👉 Browse the full list here: https://eatris.eu/publications-citing-eatris
#ResearchImpact #TranslationalMedicine
November 4, 2025 at 12:53 PM
eatris.bsky.social
📣 Stay up to date with the latest in #TranslationalMedicine.

Subscribe to Translational Trends - the EATRIS newsletter with updates, stories, and opportunities from across the #TranslationalResearch community, and beyond!

👉 Subscribe here: https://eatris.eu/eatris-mailing-lists-subscribe/
November 3, 2025 at 7:31 AM
swog.org
Our #TranslationalMedicine Link of the Week, chosen by @swog.org's Lee Ellis, MD, & Jimmy Rae, PhD:
Navigating Cancer Complexity: Integrative Multi-Omics Methodologies for Clinical Insights
doi.org/10.1177/1179...
SWOG TM Link of the Week
October 31, 2025 at 4:21 PM
eatris.bsky.social
🇮🇹 EATRIS Italy, with ELIXIR-IT & EBRAINS-Italy, recently hosted a course on #ArtificialIntelligence in Diagnostic Imaging. The course explored how AI improves diagnostic accuracy, supports clinicians & drives innovation in #TranslationalMedicine.

👉More: https://loom.ly/TPP0ApQ #EATRIS_IT
October 31, 2025 at 7:31 AM
eatris.bsky.social
🤝 Memorandum of Understanding signed in #EATRIS_LV! Rīga Stradiņš University, the Children’s Clinical University Hospital & Pauls Stradiņš Clinical University Hospital have signed an MoU to strengthen #TranslationalMedicine & international research cooperation in Latvia.

👉 https://loom.ly/CVUIN0I
October 30, 2025 at 12:44 PM
hemehub.bsky.social
🧬The second question of the day focuses on how patient-reported outcomes reflect clinical benefit after Casgevy therapy.

#Casgevy #GeneTherapy #CRISPRGeneEditing #SickleCellGeneTherapy #SickleCellDisease #Hematology #CellTherapy #TranslationalMedicine #ClinicalTrials #RareDiseases #BloodDisorders
October 29, 2025 at 7:03 PM