Scholar

Bernhard Y. Renard

H-index: 38
Biology 58%
Chemistry 17%

Reposted by Bernhard Y. Renard

judith-bernett.bsky.social
🧬🖥️So excited to show you the outcome of @pascivers.bsky.social and my latest project: "From Hype to Health Check: Critical Evaluation of Drug Response Prediction Models with DrEval" doi.org/10.1101/2025.05.26.655288, published with M. Picciani, M. Wilhelm, K. Baum & @itisalist.bsky.social.
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Overview of the DrEval framework. Via input options, implemented state-of-the-art models can be compared against baselines of varying complexity. We address obstacles to progress in the field at each point in our pipeline: Our framework is available on PyPI and nf-core and we follow FAIReR standards for optimal reproducibility. DrEval is easily extendable as demonstrated here with a pseudocode implementation of a proteomics-based random forest. Custom viability data can be preprocessed with CurveCurator, leading to more consistent data and metrics. DrEval supports five widely used datasets with application-aware train/test splits that enable detecting weak generalization. Models are free to use provided or custom cell line– and drug features. The pipeline supports randomization-based ablation studies and performs robust hyperparameter tuning for all models. Evaluation is conducted using meaningful, bias-resistant metrics to avoid inflated results from artifacts such as Simpson’s paradox. All results are compiled into an interactive HTML report. Created in https://BioRender.com.
renardlab.bsky.social
What a run! 🏃‍♀️🏃‍♂️
Last week, our group took part in the Berlin #Firmenlauf, and we had an amazing time out there, running, cheering each other on, and just enjoying the energy of the event! #TeamVibes

Thanks to everyone who made it such a memorable day 🤗 #ScienceInSneakers @hpi.bsky.social
@y.hartmar
renardlab.bsky.social
In his project in collaboration with the Icahn School of Medicine at Mount Sinai @hpims.bsky.social, he is exploring the effect of biological administration timing on treatment outcomes in patients with Inflammatory Bowel Disease. Supervised by Dr. Susanne Ibing @sibing.bsky.social.
renardlab.bsky.social
We're proud to have Akin present his ongoing master's thesis project at the European Crohn's and Colitis Organisation (ECCO)
Congress 2025!
Akin joyously standing in front of his poster titled “Morning administration of biological therapy is associated with decreased risk of treatment failure in patients with Inflammatory Bowel Disease” at the European Crohn’s and Colitis Organisation (ECCO) congress!

Reposted by Bernhard Y. Renard

helenekretzmer.bsky.social
We’re excited to share that our paper on rapid molecular classification of brain tumors has just been published in Nature Medicine!
renardlab.bsky.social
Check out the awesome opportunity to join the group of one of the brilliant minds at our chair!
jmbartoszewicz.bsky.social
I'm setting up my lab at @hpi.bsky.social, on the edge of vibrant Berlin! PhD/postdoc positions in AI for safe synthetic biology & infectious diseases (AMR), in collab with @melanianowicka.bsky.social.

Apply by Feb 24: email [email protected] with “[Open-25]” in the subject. DM for details!

Reposted by Bernhard Y. Renard

jmbartoszewicz.bsky.social
I'm setting up my lab at @hpi.bsky.social, on the edge of vibrant Berlin! PhD/postdoc positions in AI for safe synthetic biology & infectious diseases (AMR), in collab with @melanianowicka.bsky.social.

Apply by Feb 24: email [email protected] with “[Open-25]” in the subject. DM for details!
renardlab.bsky.social
Her work produces daily immunity indices for each regional location, given vaccination and infection data for different infectious diseases, which in turn can be used to, e.g., predict the spread of disease 🧬🤧🌐
renardlab.bsky.social
Ferdous Nasri presenting her work on the 'Spatio-temporal immunity index tool for infectious diseases' at the Digital Health Summit at University of Cape Town in South Africa!
Ferdous smiling in front of her poster.
renardlab.bsky.social
She has published numerous papers and presented her work at various conferences.

Her next step will focus on her research collaborations across the atlantic. 🚀
renardlab.bsky.social
Her achievements are outstanding and we are very proud to be celebrating this day with her!💐

She started her PhD as a part of the Böttinger Lab, spent some time working with Mount Sinai in NY and switched to our Lab later. She led projects with many students, one of which won the DMEA Sparks Award🏆
renardlab.bsky.social
💐Congratulations to ✨ Dr. Susanne Ibing! 🎓

Susanne, @sibing.bsky.social, successfully defended her doctoral dissertation @hpi.bsky.social this month on “Computational Strategies for Chronic Disease Characterization and Treatment by Leveraging Electronic Health Records and Omics Data” 🩻🧬👩🏼‍💻
Dr. Susanne Ibing joyously shaking hands with Prof. Bernhard Renard! Susanne defends her dissertation in front of the fully-packed room. Dr. Susanne standing proudly wearing her graduation hat and robe in front of the HPI Digital Health building smiling with all the people that participated in her dissertation defence.
renardlab.bsky.social
With an ablation study, we demonstrated the added value of information derived from clinical notes not only for the computable phenotyping, but also the disease prediction task.

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renardlab.bsky.social
When comparing coded conditions between identified cases and controls, we saw significant overrepresentation of GI-related conditions in cases, indicating the diagnostic delay of the disease.

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renardlab.bsky.social
We found that adding information on age at diagnosis extracted from the clinical notes improves the phenotyping performance and allows to better distinguish between referral and incident cases, compared phenotyping mainly relying on structured clinical data.

🧵 4/6
renardlab.bsky.social
For automated cohort identification, we compared two computable phenotyping approaches with different levels of NLP and information extracted from clinical notes incorporated.

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renardlab.bsky.social
Diagnostic delay is a common problem in Crohn’s disease, and with delayed treatment induction leading to overall worsened outcomes. This study aimed to automatically identify newly diagnosed patients to use pre-diagnostic EHR for data disease prediction.

🧵 2/6
renardlab.bsky.social
New paper: Electronic Health Records-Based Identification of Newly Diagnosed Crohn’s Disease Cases

By Susanne Ibing @sibing.bsky.social , Julian Hugo, et al., now available in Artificial Intelligence in Medicine.

authors.elsevier.com/a/1kA113KEGa...

🧵 1/6 Thread below:
authors.elsevier.com
renardlab.bsky.social
Happy New Year and a warm hello world from our group! 🥳😄
Picture of the group members smiling standing in a meeting room facing the camera.

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