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George Davey Smith

George Davey Smith is a British epidemiologist. He has been professor of clinical epidemiology at the University of Bristol since… more

George Davey Smith
H-index: 269
Biology 40%
Public Health 21%
mendelrandom.bsky.social
Just replace dark chocolate for whatever the nutritional exposure in today's news story is in the below ieureka.blogs.bristol.ac.uk/2024/12/04/d...

Reposted by: George Davey Smith

michelnivard.bsky.social
Apply to do a PhD with me, Laura Corbin, Gareth Hawkes and George Davey Smith ( @mendelrandom.bsky.social) in Bristol on identifying rare effects on health using new and innovative methods. Amazing team, great educational environment, lovely city. Forward to your undergrads wrapping up!
Shining a light on the un-common to identify novel health risk-factors - GW4 BioMed MRC DTP
Project Code MRCPHS26Br Nivard Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary Complex traits such as body mass index and height are influenced by a mixt...
gw4biomed.ac.uk
mendelrandom.bsky.social
"Triangulation: moving from correlations to causation", Cambridge School of Clinical Medicine Distinguished Lecture 2025, Thursday, October 16th, 5pm, in person or online
www.eventbrite.co.uk/e/school-of-...
mendelrandom.bsky.social
6/n between initiators and promoters of cancer, highlights the large proportion of cancer that is preventable in principle but wasn't yet preventable in practice, and offered a coherent defence of "black box" epidemiology. Here it is again: link.springer.com/article/10.1... /cont
The need for Ignorance in cancer research - European Journal of Epidemiology
European Journal of Epidemiology -
link.springer.com
mendelrandom.bsky.social
5/n it now with at least some understanding and realised it is a 5 page accessible summary of the 1977 masterpiece, of extraordinary richness. It touches on what is now known as "Peto's paradox", anticipates notions of normal tissue early mutations, revisited the distinction/cont
mendelrandom.bsky.social
4/n It is a seminal "introduction to, and apology for, multistage models" (see the introduction below, surely you can't stop reading where it leaves off?) of vast subtlety & depth. The interlibrary loan of "The need for ignorance in cancer research" arrived and I read /cont
mendelrandom.bsky.social
3/n the @IntJEpidemiol A 1977 inaccessible masterpiece with many typos Richard found the corrections he'd tried (but failed) to have made on the proofs (he'd already delayed publication by a year by being late providing his chapter); read it here! /cont academic.oup.com/ije/article/...
Epidemiology, multistage models, and short-term mutagenicity tests 1
This section is intended as an introduction to, and apology for, multistage models. Such models occupy a curious position in the world of cancer research.
academic.oup.com
mendelrandom.bsky.social
2/n no one seemed to buy anything and the rumour was it was a front for an MI5 office. I was left alone reading away, and was entranced by the sparkling language but must admit I understood hardly any of it. I recalled it when reprinting another Richard Peto chapter in/cont
mendelrandom.bsky.social
1/n I first read this sitting on a stool in the HK Lewis medical bookshop on Gower Street soon after it came out; the book was outside my budget & the rest not so interesting. It felt like the 19th century in Lewis' anachronistic shop, there were hardly any customers /cont
mendelrandom.bsky.social
A brilliant 1984 chapter in the "Encyclopaedia of Medical Ignorance" by Richard Peto anticipated much of the advances in understanding of cancer since then, and is now accessible in @SpringerNature European Journal of Epidemiology. A personal on it/ cont link.springer.com/article/10.1...
The need for Ignorance in cancer research - European Journal of Epidemiology
European Journal of Epidemiology -
link.springer.com
mendelrandom.bsky.social
Mendelian randomization (MR) was partly a response to the many epidemiological studies suggesting vitamins were protective against various diseases, only for randomised trials to be null. The story of how fallacious MR attempted to resurrect the spurious claims here academic.oup.com/ije/article/...
Erroneous epidemiological findings on vitamins: coming full circle after two decades of Mendelian randomization?
Our editorial responsibility for the International Journal of Epidemiology (IJE) started at the dawn of the current millennium, and we marked the occasion
academic.oup.com
mendelrandom.bsky.social
This will be a great lecture from a brilliant and impactful epidemiologist
johnsnowsociety.bsky.social
📢The 2025 Pumphandle Lecture will be given by:

Dr Cesar Victora, Emeritus Professor of Epidemiology at Federal University of Pelotas, Brazil!!

"From Local Insights to Global Impact: Four Decades of Child Health and Nutrition Epidemiology in Pelotas, Brazil."

More information to come.

Reposted by: George Davey Smith

johnsnowsociety.bsky.social
📢The 2025 Pumphandle Lecture will be given by:

Dr Cesar Victora, Emeritus Professor of Epidemiology at Federal University of Pelotas, Brazil!!

"From Local Insights to Global Impact: Four Decades of Child Health and Nutrition Epidemiology in Pelotas, Brazil."

More information to come.
mendelrandom.bsky.social
Basically CHD looks like a good old Farr model epidemic curve

References

Fields & subjects

Updated 1m