Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

#GRADE’s primary focus in #SystematicReviews has been on rating certainty in evidence on interventions. But in this article GRADE also provides guidance for #CertaintyofEvidence in #prognosis in which #ObservationalStudies start as high certainty evidence.

pubmed.ncbi.nlm.nih.gov/31982539/

GRADE Guidelines 28: Use of GRADE for the assessment of evidence about prognostic factors: rating certainty in identification of groups of patients with different absolute risks - PubMed

The same principles GRADE proposed for bodies of evidence addressing treatment and overall prognosis work well in assessing individual prognostic factors, both in noncontextualized and contextualized ...

pubmed.ncbi.nlm.nih.gov

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

At the recent #GuidelinesInternationalNetwork (GIN) meeting in Geneva I paid the price for my notoriety as folks cornered me, including this group lining up to have their photo taken with me.

by Gordon Guyatt — Reposted by: Lars G. Hemkens

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

At recent #GuidelinesInternationalNetwork (GIN) meeting with Thomas Agoritsas, Chair of the #MAGICEcosytemFoundation and international #GRADE methodology leader and our researcher Prashanti Eachempati, creator of the JUDGE instrument that will revolutionize GRADE education and practice.

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

The #ChronicRespiratoryQuestionnaire (CRQ) is the most responsive and valid #HealthStatusMeasurement instrument for disease-specific #QualityOfLife in patients with #COPD and other chronic respiratory conditions. This paper presents a self-report version.

pubmed.ncbi.nlm.nih.gov/11713359/

Development of a self-reported Chronic Respiratory Questionnaire (CRQ-SR) - PubMed

The CRQ-SR is a reproducible, reliable, and stable measure of health status. It compares well with the CRQ-IL but cannot be used interchangeably. The main advantage of the CRQ-SR over the CRQ-IL is th...

pubmed.ncbi.nlm.nih.gov

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by Gordon Guyatt

Reposted by: Gordon Guyatt, Eudald Carbonell

Reposted by: Gordon Guyatt

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

Clinicians increasingly rely on #chatbots for advice in managing patients. But is this advice helpful or misleading? Researchers are trying to find out. A survey of 137 studies of bot performance demonstrates their methods leave a great deal to be desired.
pubmed.ncbi.nlm.nih.gov/39903463/

Large Language Models for Chatbot Health Advice Studies: A Systematic Review - PubMed

In this systematic review of 137 chatbot health advice studies, the reporting quality was heterogeneous and may inform the development of the CHART reporting standards. Ethical, regulatory, and patien...

pubmed.ncbi.nlm.nih.gov

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by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

I am keen that the Core #GRADE series - 7 articles in
@bmj.com this spring - gets optimal use. I will therefore be available to address queries anyone has about using Core GRADE. Don’t hesitate to ask at [email protected].

pubmed.ncbi.nlm.nih.gov/40233981/

Why Core GRADE is needed: introduction to a new series in The BMJ - PubMed

Why Core GRADE is needed: introduction to a new series in The BMJ

pubmed.ncbi.nlm.nih.gov

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

#TransActivists suggest our #SystematicReviews showing low certainty evidence for outcomes of #GenderAffirming care are “pseudoscientce”. The right attacks because we suggest that banning trans care is unconscionable. This newspaper article provides a balanced perspective.
archive.ph/WsBIN

archive.ph

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by Gordon Guyatt

Reposted by: Gordon Guyatt, Thomas Piketty, Branko Milanovic , and 69 more Gordon Guyatt, Thomas Piketty, Branko Milanovic, Markus K. Brunnermeier, Douglas A. Irwin, James E. Hansen, Timnit Gebru, George M. Church, Andrew J. Lees, Anima Anandkumar, Jack Goldsmith, Dominique Reynie, Loretta Lees, Jurgen Schmidhuber, Fatih Birol, John A. List, Zoubin Ghahramani, Eric P. Xing, Richard Socher, Andrés Rodríguez‐Pose, Harry Anthony Patrinos, David Evans, Robert M. Wachter, Morgan Bazilian, William N. Goetzmann, César A. Hidalgo, Anindya Ghose, Martín Haspelmath, Frances H. Arnold, Chris Stringer, William J. Ripple, Christophe Jaffrelot, Peter J. Boettke, Justus Haucap, Andreas Peichl, Armin Nassehi, Femi Oyebode, Peter Adamson, Tim Newburn, Yong Zhao, Dawn M. Coleman, Naim Kapucu, Stephen Palmer, Matteo Maggiori, Esteban Rossi‐Hansberg, Bart D. Ehrman, Québec . Ministère de l'éducation, Tara Brabazon, Daniel Innerárity, Sarah Elaine Eaton, Hugo Ñopo, John Holbein, Vincent Geloso, Owen Davies, Douglas Holtz‐Eakin, Andrea Presbitero, Erinç Yeldan, Henry Gao, Nic Cheeseman, Kamiar Mohaddes, Jiří Přibáň, Peter Whiteford, Takanori Ida, Ajay Shah, Eduardo Gudynas, Miles Richardson, Joshua Kalla, Alberto Corsín Jiménez, Trevor Tombe, Consiglio nazionale delle ricerche, Raúl Pacheco-Vega, Paulo Gala

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

#GRADE provides guidance for rating #CertaintyofEvidence regarding accuracy of diagnostic tests. This informative paper provides details on assessing #inconsistency, #imprecision, #PublicationBias and other domains and for creating #SummaryofFindings tables.

pubmed.ncbi.nlm.nih.gov/32058069/

GRADE guidelines: 21 part 2. Test accuracy: inconsistency, imprecision, publication bias, and other domains for rating the certainty of evidence and presenting it in evidence profiles and summary of f...

Using GRADE in Cochrane and other reviews as well as World Health Organization and other guidelines helped refining the GRADE approach for rating the certainty of a body of evidence from TA studies. A...

pubmed.ncbi.nlm.nih.gov

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

Most #GRADE users are familiar with GRADE’s #EvidenceToDecision frameworks for interventions. Less so with EtD for tests. This excellent exposition provides guidance when creating or using a #DiagnosticTests and other tests (such as #screening) EtDs.

pubmed.ncbi.nlm.nih.gov/26931285/

GRADE Guidelines: 16. GRADE evidence to decision frameworks for tests in clinical practice and public health - PubMed

EtD frameworks for developing recommendations and making decisions about tests lay out the sequential steps in reviewing and assessing the different types of evidence that need to be linked.

pubmed.ncbi.nlm.nih.gov

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Reposted by: Gordon Guyatt, Timothy Snyder, Thomas Piketty , and 41 more Gordon Guyatt, Timothy Snyder, Thomas Piketty, Richard Baldwin, Pedro Domingos, Kaushik Basu, Mark C.M. van Loosdrecht, Anima Anandkumar, Anders Aslund, John A. List, Harry Anthony Patrinos, Walter Scheidel, Robb Willer, Adam M. Grant, Eudald Carbonell, Ari Laaksonen, Ed Hawkins, Chris Stringer, Steve Fuller, Andreas Löschel, Tim Newburn, Mary K. Mulcahey, Robert B. Talisse, Ive Marx, Konstantin Sonin, Johannes Haushofer, Québec . Ministère de l'éducation, Salvatore Babones, Dean Baker, Robert C. Hockett, Vincent Geloso, Benoît Cœuré, Dominique Rousseau, Christopher Elmendorf, Owen Davies, Dirk Messner, Mario Macis, Jonathan A. Parker, Jenny Kitzinger, Lilian Edwards, Michael Veale, Jonathan Birch, Timothy Graham, Paulo Gala

by Gordon Guyatt

Gordon H. Guyatt

@guyattgh.bsky.social

Our group posted: using our #GRADE #SR of #GenderAffirming care to justify denial of care is unconscionable. A #NationalPost piece decried our position. The author had been suspended by the BC College of Nursing for comments derogatory towards transgender people!
nationalpost.com/opinion/fath...

Amy Hamm: Father of 'evidence-based medicine' turns his back on science

Bullied by activists, Gordon Guyatt is now arguing against using his own findings to guide policy

nationalpost.com

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by Gordon Guyatt

References

Fields & subjects