Lightnews — Scholar-powered news

Reposted by Benoit Bruneau

BWJones @bwjones.bsky.social · 10h

My spouse pulled data from the CDC’s MMWR team on a weekly basis for her company to include with public health reports. That entire team has just been RIFed by Trump.

No more public health reports.

www.cdc.gov/mmwr/index.h...

Morbidity and Mortality Weekly Report

The MMWR series is the agency’s primary vehicle for ,,,

www.cdc.gov

6 57 81

Benoit Bruneau @benoitbruneau.bsky.social · 9h

@nytimes.com @washingtonpost.com anyone?

Aaron Rupar @atrupar.com · 14h

Trump: "Portland, I mean -- every time I look at that place it's burning down. There are fires all over the place. When a store -- there are very few of them left -- but when a store owner rebuilds a store they build it out of plywood. They don't put up storefronts anymore. They just put wood up."

1 2

Benoit Bruneau @benoitbruneau.bsky.social · 9h

I’m gonna have to sit down if I want to. Too tired.

1

Benoit Bruneau @benoitbruneau.bsky.social · 19h

Le sigh.

1

Benoit Bruneau @benoitbruneau.bsky.social · 1d

I went and looked up the studies, which had a sharp response from other scientists in the journal. So flawed and completely contradicted by other studies. Gold Standard Science, folks

2

Benoit Bruneau @benoitbruneau.bsky.social · 1d

@brutalismbot.com low budget brutalist balconies in Montreal

3

Benoit Bruneau @benoitbruneau.bsky.social · 1d

gladstone.org/news/cirm-aw...

CIRM Awards $7.5 Million in Discovery Grants to Gladstone Investigators

Two ambitious research projects led by Gladstone investigators are boosted by funds from the California Institute for Regenerative Medicine.

gladstone.org

3 1 12

Benoit Bruneau @benoitbruneau.bsky.social · 1d

Good one

1

Reposted by Benoit Bruneau

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 1d

My HPLC was definitely overlooked

www.nature.com/articles/d41...

Prizes must recognize machine contributions to discovery

The future of science will be written by humans and machines together. Awards should reflect that reality.

www.nature.com

20 57 300

Reposted by Benoit Bruneau

Robert Screaton @roblab.bsky.social · 2d

3 4

Benoit Bruneau @benoitbruneau.bsky.social · 2d

Hey Americans! How’s that baseball series going?

4 1 2

Benoit Bruneau @benoitbruneau.bsky.social · 2d

Same. Also a few very productive collaborations, many new friends, far broader insight into people and their world.

7

Benoit Bruneau @benoitbruneau.bsky.social · 2d

Go Isha! So inventive and important!

Gladstone Institutes @gladstoneinst.bsky.social · 2d

Leveraging modern scientific tools and techniques, @ishahjain.bsky.social intends to transform our understanding of the critical roles that vitamins play in health and disease.

Bringing Modern Science to Vitamin Biology: Isha Jain Wins NIH Transformative Research Award

Leveraging modern scientific tools and techniques, Jain intends to transform our understanding of the critical roles that vitamins play in health and disease.

gladstone.org

1 8

Benoit Bruneau @benoitbruneau.bsky.social · 2d

Second Nobel prize of the week for @ucberkeleyofficial.bsky.social! www.nature.com/articles/d41...

Chemistry Nobel for scientists who developed massively porous ‘super sponge’ materials

Susumu Kitagawa, Richard Robson and Omar Yaghi pioneered the creation of metal-organic frameworks, which can capture and store molecules such as carbon dioxide.

www.nature.com

5

Benoit Bruneau @benoitbruneau.bsky.social · 3d

you had me at "fat"

Reposted by Benoit Bruneau

Seema Grewal @seemagrewal.bsky.social · 3d

So sad to hear the news - John truly was an inspiration to so many, and one of a kind.

www.cam.ac.uk/research/new...

Nobel Laureate Professor Sir John Gurdon dies aged 92

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.

www.cam.ac.uk

25 98

Reposted by Benoit Bruneau

Bart Deplancke @bartdeplancke.bsky.social · 5d

🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China

Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq - Nature Genetics

This study introduces single-cell transcription factor (TF) sequencing, a single-cell barcoded and doxycycline-inducible TF overexpression approach that reveals dose-sensitive functional classes of TFs and cellular heterogeneity by mapping TF dose-dependent transcriptomic changes during the reprogramming of mouse embryonic multipotent stromal cells.

www.nature.com

2 51 140

Benoit Bruneau @benoitbruneau.bsky.social · 4d

OMFG. Rush is back on tour! www.washingtonpost.com/entertainmen...

Legendary Canadian rock band Rush will return to the road

Surviving members of Rush, Geddy Lee and Alex Lifeson, are reuniting for a 2026 concert tour with drummer Anika Nilles sitting in for the late Neil Peart.

www.washingtonpost.com

3 1 16

Benoit Bruneau @benoitbruneau.bsky.social · 4d

Now we’re talking crêpes!

1 1

Benoit Bruneau @benoitbruneau.bsky.social · 4d

Turnstile!

3

Benoit Bruneau @benoitbruneau.bsky.social · 5d

A clear opinion being expressed

7

Benoit Bruneau @benoitbruneau.bsky.social · 5d

I have no egrets

Brenda Hiles @beehiles.bsky.social · 5d

A snowy egret on Front Street in Beaufort, N.C. #birds

4 14

Benoit Bruneau @benoitbruneau.bsky.social · 5d

Rorschach's best line: "What you don't seem to understand is I'm not locked in here with you. You're locked in here with ME!"

3

Reposted by Benoit Bruneau

Olaf Falafel @ofalafel.bsky.social · 5d

Never thought I'd say this. It's
gonna be harsh and might
give you angry feelings when
you see it. I've come
up with one simple life rule:
Never ever (I know you're
gonna, but please don't)
let yourself feel stupid when
you look at the first words
down the left side of this post

12 42 190

Reposted by Benoit Bruneau

Victor Tatarskiy @greenrat.bsky.social · 8d

Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky

On the left - western blot of B16F10 cells wt and KO for CDK8. Our in house produced antibodies give a lot of unspecific bands. On the right same probes with antibodies preincubated with fixed CDK8 KO cells - there is a specific band and faint unspecific bands, which can be probably eliminated with increase of amount of KO cells.

7 49 170