Lightnews — Scholar-powered news

Reposted by Carlos Talavera-López

Jeff Mold @jeffmold.bsky.social · 17d

Interesting finding on cancer lineage tracing for SCLC www.nature.com/articles/s41...

Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer - Nature

Basal cells, rather than neuroendocrine cells, have been identified as the probable origin of small cell lung cancer and other neuroendocrine–tuft cancers, explaining neuroendocrine–tuft heterogeneity and offering new perspectives for targeting lineage plasticity.

www.nature.com

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Reposted by Carlos Talavera-López

Nature Portfolio @natureportfolio.nature.com · 28d

Nature’s Careers team spoke to a group of researchers about why they love LinkedIn, and how other scientists can use it to their advantage to harness its career-boosting and collaboration potential. #Academicsky 🧪

‘LinkedIn is like air to me’: the scientists who’ve cracked professional networking

Fans of the global social-media platform explain how best to harness its career-boosting and collaboration potential.

go.nature.com

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Carlos Talavera-López @cartalop.bsky.social · Sep 4

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Reposted by Carlos Talavera-López

Valentine Svensson @nxn.se · Jul 10

A pre-trained t-test transformer - www.nxn.se/p/a-pre-trai...

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Reposted by Carlos Talavera-López

Anshul Kundaje @anshulkundaje.bsky.social · Jun 28

One thing that really bothers me with the new "virtual cell" terminology is that it is currently largely focused on a very narrow definition of models that can predict effects of trans perturbations (gene dosage, drugs etc) on gene expression. 1/

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The Atlantic @theatlantic.com · Jun 24

“SkinnyTok’s ruthless tone rings true to many women because they’re already being so ruthless toward themselves,” Annie Joy Williams writes:

When SkinnyTok Came for Me

The body positivity movement is over.

bit.ly

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Reposted by Carlos Talavera-López

Eric Topol @erictopol.bsky.social · Jun 21

Ultraprocessed foods have "contributed to high rates of chronic disease in the United States"
They need to be regulated. @nejm.org today, the ways they can be reined in.
www.nejm.org/media/doi/fu...

Medical Media Center: New England Journal of Medicine

Much of the food consumed in the United States is ultraprocessed. Evidence indicates that ultraprocessed food, as a class, has contributed to high rates of chronic diseases.

www.nejm.org

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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · Jun 5

Let’s give a big round of applause to Jakob Jung, who has successfully defended his dissertation! 👏 Congratulations, @jabster93.bsky.social‬! The #HIRI family is celebrating with you! 🥳
Read more: www.helmholtz-hiri.de/en/newsroom/...

Jakob Jung (left) with thesis committee member Lars Barquist. Photo: HIRI / Luisa Härtig

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Lior Pachter @lpachter.bsky.social · Jun 3

liorpachter.wordpress.com/2025/06/03/e...

Epistemic failure of epistemic failure

Earlier this year I came across this interesting post by mathematician Daniel Litt, where he pondered how many intrinsically true results in mathematics have been published with erroneous proofs: D…

liorpachter.wordpress.com

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Reposted by Carlos Talavera-López

Stein Aerts @steinaerts.bsky.social · Jun 4

The deadline for the VIB.AI group leader positions is approaching - send in your CV and short research plan before 14th June to start your BioML research lab in Leuven or Ghent

VIB.AI @vibai.bsky.social · Jun 4

We want to connect:
To link model builders with data generators.
To bring together scientists asking why cells behave the way they do, and others figuring out how to model that behavior.

If you're working on AI in biology, consider joining!
https://tinyurl.com/y35m6khy

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Carlos Talavera-López @cartalop.bsky.social · Jun 1

Experiments in infrared photography.
📷 Bronica S2 & Nikkor-P 75mm f/2.8
🎞️ Ilford SPX 200

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Reposted by Carlos Talavera-López

Eliisa Kekäläinen @eliisakekalainen.bsky.social · May 27

Personal news: I have been appointed by the rector of @helsinki.fi to a tenure-track associate prof position in Clinical Microbiology and Immunology! My affiliations are with the Faculty of Medicine and HiLIFE, Institute of Life Sciences @helsinki.fi . Humbled and excited to start this new journey!

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Eva Holtkamp @evaholtkamp.bsky.social · May 25

Excited to be back at #eshg2025! Come by my poster today to check out fresh results on how rare high impact variants influence gene expression across immune cells—analyzed in 5,000 UK Biobank participants

Gagneur lab @gagneurlab.bsky.social · May 24

Eva Holtkamp @evaholtkamp.bsky.social shares insights on rare variant effects on cell type-specific gene expression in immune cells across 4,978 UK Biobank participants - catch poster P18.066.A (Sunday, 1pm)

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Stockholm University @stockholm-uni.bsky.social · May 22

A research team led from Stockholm University & @scilifelab.se has answered a long-standing question in cell biology, uncovering how the cell’s main energy currency, ATP, is transported into the endoplasmic reticulum (ER). The study is published in @nature.com.web.brid.gy
www.su.se/department-o...

Scientists reveal how energy is delivered into the cells major “shipping port” - Department of Biochemistry and Biophysics

www.su.se

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Julio Saez-Rodriguez @juliosaezrod.bsky.social · May 16

join us at ISMB iscb.bsky.social & @dreamchallenges.bsky.social - benchmarking foundation models w. @anshulkundaje.bsky.social @oldbap.bsky.social G. Stolovitzky @bowang87.bsky.social @mariabrbic.bsky.social K. Kalantar, J. Guinney supported by @ebi.embl.org @cziscience.bsky.social Tempus AI

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bioRxiv Genomics @biorxiv-genomic.bsky.social · May 16

Tissue-specific restriction of TE-derived regulatory elements safeguards cell-type identity https://www.biorxiv.org/content/10.1101/2025.05.13.653700v1

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Carlos Talavera-López @cartalop.bsky.social · May 13

📷 Zorki-1 & Industar-22 50mm f/3.5
🎞️ Fujifilm Color 400

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Carlos Talavera-López @cartalop.bsky.social · May 11

Please! No more UMAPs/t-SNEs 👇👇👇

Erik van Nimwegen @erikvannimwegen.bsky.social · May 9

Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social.
I'm so excited about this!
www.biorxiv.org/content/10.1...

Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data

Single-cell omics methods promise to revolutionize our understanding of gene regulatory processes during cell differentiation, but analysis of such data continues to pose a major challenge. Apart from...

www.biorxiv.org

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Carlos Talavera-López @cartalop.bsky.social · May 9

📷 Minolta Autocord I & Rokkor 75mm f/3.5
🎞️ Eastman Kodak double XX 250

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Carlos Talavera-López @cartalop.bsky.social · May 9

📷 Nikon-F2 & Voigtländer Nokton 58mm f/1.4
🎞️ CineStill D50

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Tuuli Lappalainen @tuuliel.bsky.social · May 5

New preprint! My (now former) postdoc @kvastad.bsky.social led this integration of GWAS and spatial transcriptomics (ST) data to identify tissue structures with enrichment of disease-implicated genes = likely causal drivers of disease biology.
www.biorxiv.org/content/10.1...

Spatial transcriptomics and genetically implicated genes identify putative causal tissue structures for complex traits

Spatially resolved transcriptomics is transforming our understanding of cellular and molecular diversity of tissues. Here, to identify tissue structures that are enriched for putatively causal disease...

www.biorxiv.org

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bioRxivpreprint @biorxivpreprint.bsky.social · May 6

Single molecule imaging reveals extracellular signal-regulated kinases dependent signal responsive spatial regulation of translation in cardiomyocytes https://www.biorxiv.org/content/10.1101/2025.05.05.652192v1

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European Research Council (ERC) @erc.europa.eu · May 5

The ERC welcomes the offer of substantial additional budget from @ec.europa.eu for the development of a new ERC funding instrument offering larger, longer-term grants, as announced by President Ursula Von der Leyen at the Sorbonne this morning.

👉 europa.eu/!NTYTTV

Choose Europe for Science: ERC welcomes new budget for 'super grants'

The Scientific Council of the European Research Council welcomes the offer of substantial additional budget from the European Commission for the development of a new ERC funding instrument offering la...

europa.eu

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Ursula von der Leyen @vonderleyen.ec.europa.eu · May 5

Europe’s choice is clear.

To put science at the heart of its economy.

To become the home of scientific freedom and collaboration.

And to welcome talent from all over the world.

I’m glad to present the first elements of our Choose Europe Initiative.

→ europa.eu/!TTbWbJ

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Carlos Talavera-López @cartalop.bsky.social · May 1

Experiments on infrared
📷 Pentax Spotmatic & Carl Zeiss Jena Pancolar 50mm f/1.8
🎞️ Rollei Infrared 400

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