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Kelli Lehto

@klehto.bsky.social

210 followers 240 following 7 posts

Assoc. Professor in neuropsychiatric genetics https://genomics.ut.ee/en/research-group-neuropsychiatric-genomics Mental health | genomics | Estonian Biobank | University of Tartu

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Kelli Lehto @klehto.bsky.social · Sep 5

Thank you!!

Kelli Lehto @klehto.bsky.social · Sep 4

I am extremely honored and beyond excited to share that I have been awarded a European Research Council Starting Grant! 🚀.🧬 🧠 💻

Grateful for the support of my colleagues and mentors — and excited for the journey ahead!

European Research Council (ERC) @erc.europa.eu · Sep 4

Are adult attention deficit hyperactivity disorder (ADHD) features truly the same as childhood ADHD?

Kelli Letho, a new ERC Starting Grantee at the University of Tartu will dissect the causal mechanisms of adult ADHD features

More 👉 buff.ly/nci5eve

#ERCStG #FontierResearch @klehto.bsky.social

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Reposted by Kelli Lehto

Hanna Maria Kariis @hannamariakariis.bsky.social · Jul 2

🎉(1/4) Excited to share that our latest paper is now published!

We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the @estbiobank.bsky.social , leveraging data from questionnaires and clinical notes using NLP.
www.nature.com/articles/s41...

Genetic influences on antidepressant side effects: a CYP2C19 gene variation and polygenic risk study in the Estonian Biobank - European Journal of Human Genetics

European Journal of Human Genetics - Genetic influences on antidepressant side effects: a CYP2C19 gene variation and polygenic risk study in the Estonian Biobank

www.nature.com

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Kelli Lehto @klehto.bsky.social · May 23

New blog post on inattention problems and life satisfaction links by our team ⬇️📣🧠

TIMESPAN @timespan-h2020.bsky.social · May 23

𝗢𝘂𝘁 𝗼𝗳 𝗙𝗼𝗰𝘂𝘀🔍 #Inattention isn’t just an #ADHD symptom - it’s a transdiagnostic risk factor. In a study of 80,000 adults, attention problems predicted lower satisfaction with work, health, relationships, and meaningfulness of life
#MentalHealth
👉 Read the full blog: timespan.eu/out-of-focus...

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Kelli Lehto @klehto.bsky.social · Jan 24

📣 New blog post on our recent paper on #ADHD genetic liability and health outcomes in people without diagnosed ADHD! @timespan-h2020.bsky.social @estbiobank.bsky.social

TIMESPAN @timespan-h2020.bsky.social · Jan 24

Recent research @estbiobank.bsky.social revealed that high genetic liability to #ADHD raises risks for 80 health conditions like #COPD (+70%), #obesity (+60%), & type 2 diabetes #T2D (+45%) - even without an ADHD diagnosis. Better screening & awareness for adults is needed!

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Kelli Lehto @klehto.bsky.social · Jan 14

We are delighted to contribute with Estonian Biobank data to this massive collaboration 🎉 So glad to see this work published! @estbiobank.bsky.social

Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · Jan 14

1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in @cellpress.bsky.social.

www.cell.com/cell/fulltex...

A thread 🧵:

Article screenshot of a genome-wide association study of major depression published in the journal Cell

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Reposted by Kelli Lehto

Mark James Adams @markjamesadams.bsky.social · Jan 14

New study from the @pgcgenetics.bsky.social:

Multi-ancestry GWAS of MDD in over half a million cases and 4 million controls.

www.cell.com/cell/fulltex...

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Trans-ancestry GWAS of major depression identifies 697 genetic variants and 308 genes, implicating neural and molecular mechanisms and drug repurposing opportunities.

www.cell.com

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Kelli Lehto @klehto.bsky.social · Dec 5

Happy to host you @dr-appie.bsky.social ❤️

Abdel Abdellaoui @dr-appie.bsky.social · Dec 5

Check out the presentation I gave in Estonia on the relationship between genetics and playing videogames 🎮🧬

I look forward to sharing more exciting results from this project in 2025!

youtu.be/q6NrDP1_T8s?...

Abdel Abdellaoui - Genetics of Video Games and Their Connections to Various Well-Being Indicators

YouTube video by EstWell

youtu.be

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Kelli Lehto @klehto.bsky.social · Nov 30

Happy to contribute with Estonian Biobank data to this important collaborative work on Borderline Personality Disorder 🧠🧬👩🏻‍💻While BPD is genetically understudied compared to other brain disorders, this paper makes significant contribution to improve the understanding of BPD!

Fabian Streit @fstreit.bsky.social · Nov 15

Happy to see this finally online: we investigated the genetic association signal of Borderline Personality Disorder in a GWAS meta-analysis with >12,000 cases. We identified 6 risk loci, and investigated shared genetic risk using genetic correlations and PheWAS
www.medrxiv.org/content/10.1...

Genome-wide association study of borderline personality disorder identifies six loci and highlights shared risk with mental and somatic disorders

Environmental and genetic risk factors contribute to the development of borderline personality disorder (BPD). We conducted the largest GWAS of BPD to date, meta-analyzing data from 12,339 cases and 1...

www.medrxiv.org

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Reposted by Kelli Lehto

Michel Nivard @michelnivard.bsky.social · Nov 28

🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.

GitHub - MichelNivard/awesome-complex-trait-genetics: A list of awesome tools for complex trait genetics.

A list of awesome tools for complex trait genetics. - MichelNivard/awesome-complex-trait-genetics

github.com

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