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Mark James Adams @markjamesadams.bsky.social · 2d

It's not every day that you get a new imputation reference panel.

allofus-anvil-imputation.terra.bio

All of Us + AnVIL Imputation Service

Efficiently and accurately complete your datasets with All of Us + AnVIL Imputation Service

allofus-anvil-imputation.terra.bio

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Reposted by Mark James Adams

Cameron Patrick @cameronpat.bsky.social · 7d

This is how I integrate Quarto and Zotero with minimal suffering (long rambling post, scroll down to the section on bibliography or search for Zotero): cameronpatrick.com/post/2023/07...

Cameron Patrick - Some Quarto PDF formatting tips, with particular reference to thesis writing

I’ve just spent most of a day faffing around trying to get Quarto to produce a nice PDF file that I like the look of and which meets my university’s formatting requirements for a PhD thesis. Maybe my ...

cameronpatrick.com

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Reposted by Mark James Adams

Leslie Brick @lesliebrickphd.bsky.social · 8d

🚨 Position Alert! 🚨
I am looking for a full-time Research Scientist 1 to join my lab in Albuquerque, NM at the Center on Alcohol, Substance Use, and Addiction (CASAA). We will be studying how stress and trauma influence cannabis and substance use. 🧠🌿 (1/5)

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Reposted by Mark James Adams

Elliot Tucker-Drob @tuckerdrob.bsky.social · 9d

Non-paywalled link to my commentary on @vw1234.bsky.social and colleagues new paper in @nature.com rdcu.be/eI2NG

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Reposted by Mark James Adams

Institute for Behavioral Genetics (IBG) @ibg.colorado.edu · 11d

University of Colorado Boulder Department of Psychology & Neuroscience is searching for TWO tenure track assistant professors. This is open to all department areas, including Behavioral, Psychiatric, and Statistical Genetics🧬 jobs.colorado.edu/jobs/JobDeta...

Assistant Professor

jobs.colorado.edu

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Mark James Adams @markjamesadams.bsky.social · 21d

'Is artificial intelligence a scientific study?'
'Not really…'

— Muriel Spark, Symposium, 1990

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Reposted by Mark James Adams

Shai Carmi @shaicarmi.bsky.social · 29d

Brilliant paper by Visscher et al.

Populations differ in traits/disease burden. Are these differences due to genetics?

Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.

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www.medrxiv.org/content/10.1...

Direct effect of genetic ancestry on complex traits in a Mexican population

Human populations differ in disease prevalences and in average values of phenotypes, but the extent to which differences are caused by genetic or environmental factors is unknown for most complex trai...

www.medrxiv.org

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Mark James Adams @markjamesadams.bsky.social · Aug 26

At a symposium celebrating the 20th year of the @genscot.bsky.social cohort. David Porteous giving an overview of the origins of the cohort, answering the question "Why Scotland"

Photograph of a presenter at a wooden podium in front of a slide with the question "Why Scotland" and bullet points "Top quality health research " and "Long standing, high quality health, social, and demographic data"

Photograph of a speaker at a podium in front of a slide showing the Generation Scotland Executive Committee ("Gang of Four")

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Reposted by Mark James Adams

Luis Apiolaza @ojala.bsky.social · Aug 26

I'll be advertising a couple of PhD scholarships (breeding/wood quality, breeding/remote sensing) in the next couple of weeks, working with me and even cooler people at the School of Forestry, University of Canterbury, Christchurch, New Zealand. They cover uni fees + stipend for 3 years.

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Mark James Adams @markjamesadams.bsky.social · Aug 26

We're looking at setting up a trusted research environment (TRE) for our cohort, to enable observability and governance, smooth rollout of updates, limit proliferation of outdated copies.

Need some pointers on how to provision these environments up so that they aren't exasperating to researchers.

Mark James Adams @markjamesadams.bsky.social · Aug 25

Good evening from Scotland.

Go Home Tae Yer Bed [Fhalbh Dhachaigh Don Leabaidh Agad] — Brògeal feat. Josie Duncan

youtu.be/__ezRGsYsuo

Go Home Tae Yer Bed - Brògeal [Acoustic Video]

YouTube video by Brògeal

youtu.be

Mark James Adams @markjamesadams.bsky.social · Aug 22

Playing screen for "I Am Not a Robot" by Marina and the Diamonds with the cover art from the album "The Family Jewels"

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Reposted by Mark James Adams

James Kitchens @kitchensjn.bsky.social · Aug 19

Excited to share our new preprint for the tskit_arg_visualizer Python package! ARGs can sometimes feel like a black box, so
@yanwong.bsky.social and I have been developing a method to programmatically drawing these graphs.

🔗 arxiv.org/abs/2508.03958

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tskit_arg_visualizer: interactive plotting of ancestral recombination graphs

Summary: Ancestral recombination graphs (ARGs) are a complete representation of the genetic relationships between recombining lineages and are of central importance in population genetics. Recent brea...

arxiv.org

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Reposted by Mark James Adams

Yuri Milaneschi @ymilaneschi.bsky.social · Aug 10

Our study in @JAMAPsych ja.ma/4lVx1eu Using 🧬 we found that disruptions in #energy pathways link to specific #MDD symptoms (⬆️ appetite & sleep). This suggests a #depression profile linked to #metabolic risk, opening doors to targeted treatments. #metabolicpsychiatry

Energy Homeostasis in Depression Pathophysiology and Heterogeneity

This study examines whether the genetic liability of metabolic, interoceptive, and motivational pathways involved in energy homeostasis regulation is associated with specific symptoms of major depress...

ja.ma

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Mark James Adams @markjamesadams.bsky.social · Aug 4

In Lilongwe for the kick-off meeting of the Genetics of Anxiety in Malawi project. Toward African-led, context-specific genomic research, supported by @wellcometrust.bsky.social

Meeting at the Kwaza Arts centre.

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Reposted by Mark James Adams

Vivek V. Venkataraman @vivek123.bsky.social · Jul 31

"Behavior drives morphological change during human evolution"

Our new article is out in @science.org today

www.science.org/doi/10.1126/...

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Reposted by Mark James Adams

Jonathan Pritchard @jkpritch.bsky.social · Jul 29

Thanks! This is amazing! So the term 'Manhattan Plot' is not originally a GWAS term at all.

Screenshotting the image here from a 1994 book on nuclear physics, for others who may be interested:

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Mark James Adams @markjamesadams.bsky.social · Jul 27

www.theguardian.com/education/20...

Edinburgh University had ‘outsized’ role in creating racist scientific theories, inquiry finds

Investigation finds one of Britain’s oldest and most prestigious universities benefited from transatlantic slavery and was haven for white supremacist theories

www.theguardian.com

Mark James Adams @markjamesadams.bsky.social · Jul 27

The University of Edinburgh has published its Race Review.

The report goes way deeper than just ties to slavery: "…the UoE formed a central point in a network of knowledge about 'civilization' and 'race' from the period of the Enlightenment onward."

www.ed.ac.uk/about/race-r...

Review of Race and History | The University of Edinburgh

The academically-led review explores historic racial and colonial injustices, including enslavement, linked to the University as well as reassessing current policies and procedures.

www.ed.ac.uk

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Reposted by Mark James Adams

Genetics Society of America @genetics-gsa.bsky.social · Jul 25

In #GENETICS, Williams et al. present a novel statistics—haplotype score—for summarizing identity-by-descent (IBD) sharing that can distinguish half-sibling pairs from avuncular or grandparent-grandchildren pairs and assign individuals to ancestor vs descendant generation.

buff.ly/SaZP3CA

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Mark James Adams @markjamesadams.bsky.social · Jul 25

Guidance discusses bias and inaccuracy, and potential harms to your own learning capacity, society, and the planet.

I like the idea that if you use generative AI, you need to include your prompts in an appendix.

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Mark James Adams @markjamesadams.bsky.social · Jul 25

My university has new guidance about generative AI. Requirements and restrictions are set on a course-by-course basis, but AI outputs must not be presented as a student's own work and the exact use must be acknowledged.

information-services.ed.ac.uk/computing/co...

Using generative AI in your studies: guidelines for students | Computing | Information Services

• The University trusts you to act with integrity in your use of generative AI for your studies. • It does not ban the use of generative AI, though its use is restricted for assessment. • Some of your...

information-services.ed.ac.uk

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Mark James Adams @markjamesadams.bsky.social · Jul 25

If you are new to GWAS, the lectures by Matti Pirinen are a good place to start. Conceptual foundations rather than how to use software.

www.mv.helsinki.fi/home/mjxpiri...

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Reposted by Mark James Adams

Na Cai @caina89.bsky.social · Jul 24

Very happy to share our new paper now on @medrxivpreprint: “Genetic risk effects on psychiatric disorders act in sets”, a great effort led my PhD student @jolienrietkerk.bsky.social, and performed together with collaborators Andy Dahl, Jonathan Flint, Andrew Schork etc. Thread 1/n

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Reposted by Mark James Adams

Mallory Freeberg @malloryfreeberg.bsky.social · Jul 23

🧬 New @emblebi.bsky.social service beta launched:
Perturbation Catalogue

🔎 Browse genetic perturbation datasets
🧠 Train models
🧬 Interpret variant function
🧭 Explore gene dependencies

Search, test APIs, suggest datasets, send feedback!
🔗 www.ebi.ac.uk/perturbation...

Funded by @opentargets.org

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