Lightnews — Scholar-powered news

Reposted by Spagnoli_Lab.

Nature Reviews Gastroenterology & Hepatology @natrevgastrohep.nature.com · 3h

ICYMI: New online! Advances in liver and pancreas organoids: how far we have come and where we go next

Advances in liver and pancreas organoids: how far we have come and where we go next

Nature Reviews Gastroenterology & Hepatology, Published online: 10 October 2025; doi:10.1038/s41575-025-01116-1Advances in organoid culture have enabled the modelling of many aspects of organs in vitro, transforming experimental biology. This Review provides a comprehensive overview of the current and emerging liver and pancreas organoid technologies and discusses current limitations and future directions.

www.nature.com

2 1

Reposted by Spagnoli_Lab.

Sigolène Meilhac @meilhacsigolene.bsky.social · 15d

New publication :
Despite being a core member of the PCP pathway, Vangl2 can play roles unrelated to planar polarity. This is the case during mouse heart morphogenesis.

bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · Sep 5

VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity https://www.biorxiv.org/content/10.1101/2025.09.05.674213v1

1 6 12

Reposted by Spagnoli_Lab.

Kara McKinley @karalmckinley.bsky.social · 1d

Lab’s 1st preprint!

Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.

@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.

He is on the job market!

Çağrı Çevrim @cagricevrim.bsky.social · 1d

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵

Induction of menstruation in mice reveals the regulation of menstrual shedding

During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

www.biorxiv.org

12 59 220

Reposted by Spagnoli_Lab.

The Company of Biologists @biologists.bsky.social · 1d

It is with great sadness that we heard of John Gurdon’s passing this week. Not just one of our 100 extraordinary biologists, but truly one of a kind, he was a pioneer, whose vision and personality inspired biologists worldwide.

1 5 30

Reposted by Spagnoli_Lab.

James Briscoe @jamesbriscoe.bsky.social · 1d

The @crick.ac.uk is recruiting Early Career Group Leaders

- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology

Deadline 27 Nov

www.crick.ac.uk/careers-stud...

Early career group leaders

We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

www.crick.ac.uk

2 150 140

Reposted by Spagnoli_Lab.

Barral Lab @barrallab.bsky.social · 2d

Looking for a PhD for 2026? We have 2 projects in collaboration with Clare Bennett (UCL) looking at macrophage metabolism in breast cancer. Check them out! @cruk-cityoflondon.bsky.social

www.colcc.ac.uk/2026-phd-pro...

crukradnet.colcc.ac.uk/phd-students...

10 5

Reposted by Spagnoli_Lab.

Alberto Elosegui-Artola @aeloseguiartola.bsky.social · 2d

Don’t miss the exciting ISSCR Webinar: Integrating Biophysics into Stem Cell Biology next Tuesday October 14!
The webinar features paired tandem talks that brings together experimentalists and theorists working at the interface of stem cell biology and biophysics. 1/2
www.isscr.org/upcoming-pro...

www.isscr.org

1 4 9

Reposted by Spagnoli_Lab.

Wellcome Trust @wellcometrust.bsky.social · 3d

We're funding doctoral programmes to train the next generation of clinically-active academic leaders. 🩺

This call continues our commitment to supporting healthcare professionals in research careers.

Applications are open now. Here’s what you need to know 🧵

1 12 8

Reposted by Spagnoli_Lab.

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · 3d

John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died.
Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology.
More: www2.mrc-lmb.cam.ac.uk/john-gurdon-...
#LMBNews

Black and white portrait of John Gurdon, 1971

3 32 99

Reposted by Spagnoli_Lab.

James Briscoe @jamesbriscoe.bsky.social · 4d

Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...

Professor Sir John Gurdon FRS (1933-2025) | Magdalene College

Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.

www.magd.cam.ac.uk

7 100 190

Reposted by Spagnoli_Lab.

Current Biology @currentbiology.bsky.social · 4d

“For Gurdon to continue in biology would be a complete waste of time both for him and for those who would have to teach him”

He proved them wrong! RIP John Gurdon

www.cell.com/current-biol...

John Gurdon

John Gurdon is at the Wellcome Trust/Cancer Research UK Institute of Cancer and Developmental Biology in Cambridge. Educated at Eton and Christ Church, Oxford, he changed from classics to zoology. Dur...

www.cell.com

14 36

Reposted by Spagnoli_Lab.

Nature @nature.com · 5d

This year’s Nobel Prize in Physiology or Medicine has been awarded to three scientists for discovering a class of immune cells that help to prevent the body from attacking its own tissues

go.nature.com/3VNrH1s

Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

go.nature.com

2 40 120

Reposted by Spagnoli_Lab.

bioRxiv Genomics @biorxiv-genomic.bsky.social · 8d

Latent plasticity of the human pancreas across development, health, and disease. https://www.biorxiv.org/content/10.1101/2025.10.01.679230v1

2 4

Reposted by Spagnoli_Lab.

Francis Lynn 🇨🇦 @nictitate.bsky.social · Mar 10

We're looking for postdoctoral scholars to join our team in Vancouver 🇨🇦. We work on cell-based approaches aimed at curing type 1 diabetes. Bring your own ideas for projects or work on one that's already funded! More details here: www.nature.com/naturecareer...

Postdoctoral Research Fellow - Vancouver, British Columbia (CA) job with University of British Columbia Department of Surgery | 12837375

The successful candidate will work on a project developing cell-based therapies for those living with type 1 diabetes (T1D).

www.nature.com

23 20

Reposted by Spagnoli_Lab.

European Commission @ec.europa.eu · 9d

#ChooseEurope for Science is live!

With €22.5 million under #MSCA, we’re funding organisations to:

🔬 Host postdoctoral researchers in all fields
🔬 Offer stable jobs and great working conditions
🔬 Create long-term career prospects

Europe is where science thrives.

More → link.europa.eu/6JhtHp

A visual featuring a black-and-white photo of Marie Skłodowska-Curie. On the left, text reads "Choose EUROPE for Science." Below it says, "Marie Skłodowska-Curie Actions €22.5 million for researchers." On the right is the European Union flag with yellow stars on a blue background.

3 62 190

Reposted by Spagnoli_Lab.

Emma Rawlins @labrawlins.bsky.social · 9d

Looking forward to working with new colleagues on a collaborative project in lung disease modelling and transcriptomics - please share! And email Jenny @jennydickens41.bsky.social, or me, with any questions. 😀

www.jobs.cam.ac.uk/job/52936/

Research Associate: Human Lung Disease Mechanisms (Fixed Term) - Job Opportunities - University of Cambridge

Research Associate: Human Lung Disease Mechanisms (Fixed Term) in the Gurdon Institute at the University of Cambridge.

www.jobs.cam.ac.uk

9 7

Spagnoli_Lab. @labspagnoli.bsky.social · 11d

Merci @shukryjhabib.bsky.social for the fabulous meeting and great hospitality in Lausanne ! 🧪🧫🔬🎶
Looking forward to the next #L2RM!

Spagnoli_Lab. @labspagnoli.bsky.social · 12d

Congratulations Sara 🎉 ! This is a really interesting and elegant study !!!

1 1

Reposted by Spagnoli_Lab.

Spagnoli_Lab. @labspagnoli.bsky.social · 16d

🚀 Exciting news!

Islet Biology is back @keystonesymposia.bsky.social !!!
Don’t miss the chance to register for this exciting conference!

🚨Early-bird registration is NOW OPEN --- see below ⤵️
#KSDiabetes26 🌲🌲🌲

Olov Andersson @o-andersson-lab.bsky.social · 17d

Join us for the revival of the Islet Biology and Diabetes Keystone symposia in Breckenridge, Colorado on March 16-19, 2026, for great science and great skiing. You can register now for early bird rates: lnkd.in/dw59T7tc Joint with Gut-Brain Axis. @linnemannlab.bsky.social Erica Nishimura, Barak Blum

2 3

Spagnoli_Lab. @labspagnoli.bsky.social · 16d

🚀 Exciting news!

Islet Biology is back @keystonesymposia.bsky.social !!!
Don’t miss the chance to register for this exciting conference!

🚨Early-bird registration is NOW OPEN --- see below ⤵️
#KSDiabetes26 🌲🌲🌲

Olov Andersson @o-andersson-lab.bsky.social · 17d

Join us for the revival of the Islet Biology and Diabetes Keystone symposia in Breckenridge, Colorado on March 16-19, 2026, for great science and great skiing. You can register now for early bird rates: lnkd.in/dw59T7tc Joint with Gut-Brain Axis. @linnemannlab.bsky.social Erica Nishimura, Barak Blum

2 3

Spagnoli_Lab. @labspagnoli.bsky.social · 19d

Congratulations Alexis!!! 🎉🎉

1 1

Reposted by Spagnoli_Lab.

John Wallingford @jbwallingford.bsky.social · 26d

Side hustle level-up! My book, IN THE BEGINNING, will be published by @harperonebooks.bsky.social in 2027! It's about the human embryo, how it gets built, and what it means for where we come from and where we're going.
@harpercollins.bsky.social (1/2)
@socdevbio.bsky.social
#devbiol
#scicomm

6 15 85

Reposted by Spagnoli_Lab.

Max-Planck-Gesellschaft @maxplanck.de · 26d

Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...

Graphic with a blue background and light green dots. The text 'call for applications' appears in green, and 'Ausschreibung' in white. A white arrow on the right points diagonally upward.

100 92

Reposted by Spagnoli_Lab.

Jim Johnson 🇨🇦 @jimjohnsonsci.bsky.social · 27d

Hey friends and colleagues ! Vancouver Coastal Health Research Institute - VCHRI is now on Bluesky, give them a follow @vchresearch.bsky.social

Vancouver Coastal Health Research Institute (@vchresearch.bsky.social)

Vancouver Coastal Health Research Institute — Leading innovative research with health impact in Canada. vchri.ca

vchresearch.bsky.social

1 7 14

Reposted by Spagnoli_Lab.

Sara Wickstrom @sarawickstrom.bsky.social · 29d

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

Computational image analyst (m/f/d)

The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a

jobs.mpi-muenster.mpg.de

1 86 87